Dipak Sapkota

Førsteamanuensis - Institutt for oral biologi
Bilde av Dipak Sapkota
English version of this page
Telefon +47-22840331
Brukernavn
Besøksadresse Sognsvannsveien 10 Domus Odontologica 0372 OSLO
Postadresse Postboks 1052 Blindern 0316 OSLO

Teaching:

MED1100, MED2200, OD2100, TP2100

Emneord: S100 proteins, miRNA, oral precancer and cancer, transcriptome analysis, functional assays, modulation of gene expression, in vivo models of carcinogenesis

Publikasjoner

  • Fluge, Øystein; Mella, Olav; Bruland, Ove; Risa, Kristin; Dyrstad, Sissel Elisabeth; Alme, Kine; Rekeland, Ingrid Gurvin; Sapkota, Dipak; Røsland, Gro Vatne; Fosså, Alexander; Ktoridou-Valen, Irini; Lunde, Sigrid; Sørland, Kari; Lien, Katarina; Herder, Ingrid; Thurmer, Hanne; Gotaas, Merete E; Baranowska, Katarzyna Anna; Bohnen, Louis M.L.J.; Schäfer, Christoph; Mccann, Adrian; Sommerfelt, Kristian; Helgeland, Lars; Ueland, Per Magne; Dahl, Olav & Tronstad, Karl Johan (2016). Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome.. JCI Insight.  ISSN 2379-3708.  1 . doi: 10.1172/jci.insight.89376
  • Lunde, Sigrid; Kristoffersen, Einar Klæboe; Sapkota, Dipak; Risa, Kristin; Dahl, Olav; Bruland, Ove; Mella, Olav & Fluge, Øystein (2016). Serum BAFF and APRIL levels, T-lymphocyte subsets, and immunoglobulins after B-cell depletion using the monoclonal anti-CD20 antibody rituximab in myalgic encephalopathy/chronic fatigue syndrome. PLoS ONE.  ISSN 1932-6203.  11:e0161226(8) . doi: 10.1371/journal.pone.0161226
  • Sharma, Sunita; Sapkota, Dipak; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Bruland, Ove & Mustafa, Kamal Babikeir Eln (2016). Adenoviral Mediated Expression of BMP2 by Bone Marrow Stromal Cells cultured in 3D Copolymer Scaffolds Enhances Bone Formation. PLoS ONE.  ISSN 1932-6203. . doi: 10.1371/journal.pone.0147507 Fulltekst i vitenarkiv.
  • Fluge, Øystein; Risa, Kristin; Lunde, Sigrid; Alme, Kine; Rekeland, Ingrid Gurvin; Sapkota, Dipak; Kristoffersen, Einar Klæboe; Sørland, Kari; Bruland, Ove; Dahl, Olav & Mella, Olav (2015). B-lymphocyte depletion in myalgic encephalopathy/chronic fatigue syndrome. An open-label phase II study with rituximab maintenance treatment. PLoS ONE.  ISSN 1932-6203.  10:e0129898(7) . doi: 10.1371/journal.pone.0129898
  • Min, Anjie; Zhu, Chao; Peng, Shuping; Rajthala, Saroj; Costea, Daniela Elena & Sapkota, Dipak (2015). MicroRNAs as important players and biomarkers in oral carcinogenesis. BioMed Research International.  ISSN 2314-6133.  2015:186904 . doi: 10.1155/2015/186904 Fulltekst i vitenarkiv.
  • Osman, Tarig Al-Hadi; Parajuli, Himalaya; Sapkota, Dipak; Ahmed, Israa A.H.; Johannessen, Anne Christine & Costea, Daniela Elena (2015). The low-affinity nerve growth factor receptor p75NTR identifies a transient stem cell-like state in oral squamous cell carcinoma cells. Journal of Oral Pathology & Medicine.  ISSN 0904-2512.  44(6), s 410- 419 . doi: 10.1111/jop.12251 Fulltekst i vitenarkiv.
  • Sapkota, Dipak; Bruland, Ove; Parajuli, Himalaya; Osman, Tarig Al-Hadi; Teh, Muy-Teck; Johannessen, Anne Christine & Costea, Daniela Elena (2015). S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma. BMC Cancer.  ISSN 1471-2407.  15:631 . doi: 10.1186/s12885-015-1622-1 Fulltekst i vitenarkiv.
  • Liang, Xiao; Osman, Tarig Al-Hadi; Sapkota, Dipak; Neppelberg, Evelyn; Lybak, Stein; Liavaag, Per Gunnar; Johannessen, Anne Christine; Jacobsen, Hege; Enger, Per Øyvind; Costea, Daniela Elena & Wang, Jian (2014). Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.. European Journal of Cancer.  ISSN 0959-8049.  50(18), s 3262- 3270 . doi: 10.1016/j.ejca.2014.09.010 Fulltekst i vitenarkiv.
  • Sapkota, Dipak; Costea, Daniela Elena; Ibrahim, Salah Osman; Johannessen, Anne Chr. & Bruland, Ove (2013). S100A14 interacts with S100A16 and regulates its expression in human cancer cells. PLoS ONE.  ISSN 1932-6203.  8(9) . doi: 10.1371/journal.pone.0076058
  • Dabija-Wolter, Gabriela; Sapkota, Dipak; Cimpan, Mihaela Roxana; Neppelberg, Evelyn; Bakken, Vidar & Costea, Daniela Elena (2012). Limited in-depth invasion of Fusobacterium nucleatum into in vitro reconstructed human gingiva. Archives of Oral Biology.  ISSN 0003-9969.  57(4), s 344- 351 . doi: 10.1016/j.archoralbio.2011.09.015
  • Jalouli, Jamshid; Jalouli, Miranda M; Sapkota, Dipak; Ibrahim, Salah Osman; Larsson, Per-Anders & Sand, Lars (2012). Human papilloma virus, herpes simplex virus and epstein barr virus in oral squamous cell carcinoma from eight different countries. Anticancer Research.  ISSN 0250-7005.  32(2), s 571- 580
  • Sand, Lars; Jalouli, Miranda M; Jalouli, Jamshid; Sapkota, Dipak & Ibrahim, Salah Osman (2012). p53 Codon 72 polymorphism in oral exfoliated cells in a Sudanese population. In Vivo.  ISSN 0258-851X.  26(1), s 59- 62
  • Sapkota, Dipak; Costea, Daniela Elena; Blø, Magnus; Bruland, Ove; Lorens, James B.; Vasstrand, Endre N. & Ibrahim, Salah Osman (2012). S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest. Oral Oncology.  ISSN 1368-8375.  48(3), s 219- 225 . doi: 10.1016/j.oraloncology.2011.10.001
  • Fluge, Øystein; Bruland, Ove; Risa, Kristin; Storstein, Anette; Kristoffersen, Einar Klæboe; Sapkota, Dipak; Næss, Halvor; Dahl, Olav; Nyland, Harald Inge & Mella, Olav (2011). Benefit from B-lymphocyte depletion using the anti-CD20 antibody rituximab in chronic fatigue syndrome. A double-blind and placebo-controlled study. PLoS ONE.  ISSN 1932-6203.  6(10) . doi: 10.1371/journal.pone.0026358
  • Jalouli, Miranda; Jalouli, Jamshid; Sapkota, Dipak; Ibrahim, Salah Osman; Sand, Lars & Hirsch, Jan-M (2011). Differential expression of apoptosis, cell cycle regulation and intermediate filament genes in oral squamous cell carcinomas associated with toombak use in Sudan. Anticancer Research.  ISSN 0250-7005.  31(10), s 3345- 3351
  • Sapkota, Dipak; Bruland, Ove; Costea, Daniela Elena; Haugen, Hallvard; Vasstrand, Endre N. & Ibrahim, Salah Osman (2011). S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9. European Journal of Cancer.  ISSN 0959-8049.  47(4), s 600- 610 . doi: 10.1016/j.ejca.2010.10.012
  • Jalouli, Jamshid; Ibrahim, Salah Osman; Mehrotra, Ravi; Jalouli, Miranda M; Sapkota, Dipak; Larsson, Per Anders & Hirsch, Jan-M. (2010). Prevalence of viral (HPV, EBV, HSV) infections in oral submucous fibrosis and oral cancer from India. Acta Oto-Laryngologica.  ISSN 0001-6489.  130(11), s 1306- 1311 . doi: 10.3109/00016481003782041
  • Jalouli, Jamshid; Ibrahim, Salah Osman; Sapkota, Dipak; Jalouli, Miranda M; Vasstrand, Endre N.; Hirsch, Jan M & Larsson, Per Anders (2010). Presence of human papilloma virus, herpes simplex virus and Epstein-Barr virus DNA in oral biopsies from Sudanese patients with regard to toombak use. Journal of Oral Pathology & Medicine.  ISSN 0904-2512.  39(8), s 599- 604 . doi: 10.1111/j.1600-0714.2010.00910.x Vis sammendrag
  • Sapkota, Dipak; Bruland, Ove; Bøe, Olav Egil; Bakeer, Hala; Elgindi, O. A-Aziz; Vasstrand, Endre N. & Ibrahim, Salah Osman (2008). Expression profile of the S100 gene family members in oral squamous cell carcinomas. Journal of Oral Pathology & Medicine.  ISSN 0904-2512.  37(10), s 607- 615 . doi: 10.1111/j.1600-0714.2008.00683.x

Se alle arbeider i Cristin

  • Parajuli, Himalaya; Sapkota, Dipak; Suliman, Salwa; McCormack, Emmet; Johannessen, Anne Christine; Gullberg, Donald & Costea, Daniela Elena (2015). Expression of integrin α-11 by carcinoma associated fibroblasts modulates oral squamous cell carcinoma behaviour.
  • Rajthala, Saroj; Parajuli, Himalaya; Sapkota, Dipak; Gullberg, Donald; Johannessen, Anne Christine & Costea, Daniela Elena (2015). Expression of integrin α-11 by carcinoma associated fibroblasts modulates oral squa- mous cell carcinoma behaviour.
  • Rolland Jacobsen, Martha; Sapkota, Dipak; Johannessen, Anne Christine & Costea, Daniela Elena (2015). Oral premalignant lesions overexpress the collagen-elastin crosslinking enzyme LOXL4.
  • Sapkota, Dipak; Costea, Daniela Elena; himalaya, parajuli; Osman, Tarig Al-Hadi; Bruland, Ove & Johannessen, AC (2014). Role of S100A16 in Differentiation of Oral Squamous Cell Carcinoma.
  • Sapkota, Dipak (2011). S100 Gene Family members in Oral Squamous Cell Carcinomas (OSCCs): Functional Characterization of S100A14 in Proliferation and Invasion of OSCC Derived Cells.
  • Costea, Daniela Elena; Osman, Amani Hamza Ali; Ipatova, A; Sapkota, Dipak; Neppelberg, Evelyn & Lybak, S (2009). Enhanced self-renewal properties of transformed oral epithelial cells after interactions with stromal fibroblasts. Oral Oncology.  ISSN 1368-8375.  s 92- 93 . doi: 10.1016/j.oos.2009.06.194
  • Osman, Amani Hamza Ali; Costea, Daniela Elena; Tsinkalovsky, Oleg; Sapkota, Dipak; Vintermyr, Olav Karsten & Johannessen, Anne Chr. (2009). Phenotypic and functional differences between oral carcinoma-associated fibroblasts and normal oral fibroblasts. Oral Oncology.  ISSN 1368-8375.  s 221- 221 . doi: 10.1016/j.oos.2009.06.586
  • Sapkota, Dipak; Bruland, Ove; Vasstrand, Endre N. & Ibrahim, Salah Osman (2009). Transcriptome signature of the extracellular matrix and adhesion molecules in oral squamous cell carcinomas from sudanese N-nitrosamine rich toombak users. Oral Oncology.  ISSN 1368-8375.  s 99- 100 . doi: 10.1016/j.oos.2009.06.215
  • Sapkota, Dipak; Costea, DE; Bruland, Ove; Vasstrand, Endre N. & Ibrahim, SO (2009). Expression profile of cell adhesion and matrix molecules in oral cancer.
  • Sapkota, Dipak; Bruland, Ove; Vasstrand, Endre N. & Ibrahim, Salah Osman (2008). Down-regulated expression of S100 gene family members in OSCCs.

Se alle arbeider i Cristin

Publisert 5. mai 2017 09:35 - Sist endret 26. okt. 2017 14:08

Prosjekter

  • 1. S100A14 and S100A16 proteins in oral cancer: Functional roles, prognostic and therapeutic values
  • 2. miRNA in oral cancer stroma: expression profile, functional roles and prognostic value
  • 3. Development and validation of immunohistochemistry based Quantative Malignancy Index Diagnostic System (qMIDS) for oral cancer diagnostics and personalized therapy
  • 4. Epidemiological study of head and neck cancer in Nepal