Dipak Sapkota

Førsteamanuensis - Institutt for oral biologi
Bilde av Dipak Sapkota
English version of this page
Telefon +47-22840331
Brukernavn
Besøksadresse Sognsvannsveien 10 Domus Odontologica 0372 OSLO
Postadresse Postboks 1052 Blindern 0316 OSLO

Teaching:

MED1100, MED2200, OD2100, TP2100

Emneord: S100 proteins, miRNA, oral precancer and cancer, transcriptome analysis, functional assays, modulation of gene expression, in vivo models of carcinogenesis

Publikasjoner

  • Sharma, Sunita; Sapkota, Dipak; Xue, Ying; Rajthala, Saroj; Yassin, Mohammed Ahmed Alamin Yousif; Finne-Wistrand, Anna & Mustafa, Kamal Babikeir Eln (2018). Delivery of VEGFA in bone marrow stromal cells seeded in copolymer scaffold enhances angiogenesis, but is inadequate for osteogenesis as compared with the dual delivery of VEGFA and BMP2 in a subcutaneous mouse model. Stem Cell Research & Therapy.  ISSN 1757-6512.  9:23, s 1- 13 . doi: 10.1186/s13287-018-0778-4
  • Fluge, Øystein; Mella, Olav; Bruland, Ove; Risa, Kristin; Dyrstad, Sissel Elisabeth; Alme, Kine; Rekeland, Ingrid Gurvin; Sapkota, Dipak; Røsland, Gro Vatne; Fosså, Alexander; Ktoridou-Valen, Irini; Lunde, Sigrid; Sørland, Kari; Lien, Katarina; Herder, Ingrid; Thurmer, Hanne; Gotaas, Merete E; Baranowska, Katarzyna Anna; Bohnen, Louis M.L.J.; Schäfer, Christoph; Mccann, Adrian; Sommerfelt, Kristian; Helgeland, Lars; Ueland, Per Magne; Dahl, Olav & Tronstad, Karl Johan (2016). Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome.. JCI Insight.  ISSN 2379-3708.  1 . doi: 10.1172/jci.insight.89376
  • Lunde, Sigrid; Kristoffersen, Einar Klæboe; Sapkota, Dipak; Risa, Kristin; Dahl, Olav; Bruland, Ove; Mella, Olav & Fluge, Øystein (2016). Serum BAFF and APRIL levels, T-lymphocyte subsets, and immunoglobulins after B-cell depletion using the monoclonal anti-CD20 antibody rituximab in myalgic encephalopathy/chronic fatigue syndrome. PLoS ONE.  ISSN 1932-6203.  11:e0161226(8) . doi: 10.1371/journal.pone.0161226
  • Sharma, Sunita; Sapkota, Dipak; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Bruland, Ove & Mustafa, Kamal Babikeir Eln (2016). Adenoviral Mediated Expression of BMP2 by Bone Marrow Stromal Cells cultured in 3D Copolymer Scaffolds Enhances Bone Formation. PLoS ONE.  ISSN 1932-6203. . doi: 10.1371/journal.pone.0147507 Fulltekst i vitenarkiv.
  • Fluge, Øystein; Risa, Kristin; Lunde, Sigrid; Alme, Kine; Rekeland, Ingrid Gurvin; Sapkota, Dipak; Kristoffersen, Einar Klæboe; Sørland, Kari; Bruland, Ove; Dahl, Olav & Mella, Olav (2015). B-lymphocyte depletion in myalgic encephalopathy/chronic fatigue syndrome. An open-label phase II study with rituximab maintenance treatment. PLoS ONE.  ISSN 1932-6203.  10:e0129898(7) . doi: 10.1371/journal.pone.0129898
  • Min, Anjie; Zhu, Chao; Peng, Shuping; Rajthala, Saroj; Costea, Daniela Elena & Sapkota, Dipak (2015). MicroRNAs as important players and biomarkers in oral carcinogenesis. BioMed Research International.  ISSN 2314-6133.  2015:186904 . doi: 10.1155/2015/186904 Fulltekst i vitenarkiv.
  • Osman, Tarig Al-Hadi; Parajuli, Himalaya; Sapkota, Dipak; Ahmed, Israa A.H.; Johannessen, Anne Christine & Costea, Daniela Elena (2015). The low-affinity nerve growth factor receptor p75NTR identifies a transient stem cell-like state in oral squamous cell carcinoma cells. Journal of Oral Pathology & Medicine.  ISSN 0904-2512.  44(6), s 410- 419 . doi: 10.1111/jop.12251 Fulltekst i vitenarkiv.
  • Sapkota, Dipak; Bruland, Ove; Parajuli, Himalaya; Osman, Tarig Al-Hadi; Teh, Muy-Teck; Johannessen, Anne Christine & Costea, Daniela Elena (2015). S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma. BMC Cancer.  ISSN 1471-2407.  15:631 . doi: 10.1186/s12885-015-1622-1 Fulltekst i vitenarkiv.
  • Liang, Xiao; Osman, Tarig Al-Hadi; Sapkota, Dipak; Neppelberg, Evelyn; Lybak, Stein; Liavaag, Per Gunnar; Johannessen, Anne Christine; Jacobsen, Hege; Enger, Per Øyvind; Costea, Daniela Elena & Wang, Jian (2014). Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.. European Journal of Cancer.  ISSN 0959-8049.  50(18), s 3262- 3270 . doi: 10.1016/j.ejca.2014.09.010 Fulltekst i vitenarkiv.
  • Sapkota, Dipak; Costea, Daniela Elena; Ibrahim, Salah Osman; Johannessen, Anne Chr. & Bruland, Ove (2013). S100A14 interacts with S100A16 and regulates its expression in human cancer cells. PLoS ONE.  ISSN 1932-6203.  8(9) . doi: 10.1371/journal.pone.0076058
  • Dabija-Wolter, Gabriela; Sapkota, Dipak; Cimpan, Mihaela Roxana; Neppelberg, Evelyn; Bakken, Vidar & Costea, Daniela Elena (2012). Limited in-depth invasion of Fusobacterium nucleatum into in vitro reconstructed human gingiva. Archives of Oral Biology.  ISSN 0003-9969.  57(4), s 344- 351 . doi: 10.1016/j.archoralbio.2011.09.015
  • Jalouli, Jamshid; Jalouli, Miranda M; Sapkota, Dipak; Ibrahim, Salah Osman; Larsson, Per-Anders & Sand, Lars (2012). Human papilloma virus, herpes simplex virus and epstein barr virus in oral squamous cell carcinoma from eight different countries. Anticancer Research.  ISSN 0250-7005.  32(2), s 571- 580
  • Sand, Lars; Jalouli, Miranda M; Jalouli, Jamshid; Sapkota, Dipak & Ibrahim, Salah Osman (2012). p53 Codon 72 polymorphism in oral exfoliated cells in a Sudanese population. In Vivo.  ISSN 0258-851X.  26(1), s 59- 62
  • Sapkota, Dipak; Costea, Daniela Elena; Blø, Magnus; Bruland, Ove; Lorens, James B.; Vasstrand, Endre N. & Ibrahim, Salah Osman (2012). S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest. Oral Oncology.  ISSN 1368-8375.  48(3), s 219- 225 . doi: 10.1016/j.oraloncology.2011.10.001
  • Fluge, Øystein; Bruland, Ove; Risa, Kristin; Storstein, Anette; Kristoffersen, Einar Klæboe; Sapkota, Dipak; Næss, Halvor; Dahl, Olav; Nyland, Harald Inge & Mella, Olav (2011). Benefit from B-lymphocyte depletion using the anti-CD20 antibody rituximab in chronic fatigue syndrome. A double-blind and placebo-controlled study. PLoS ONE.  ISSN 1932-6203.  6(10) . doi: 10.1371/journal.pone.0026358
  • Jalouli, Miranda; Jalouli, Jamshid; Sapkota, Dipak; Ibrahim, Salah Osman; Sand, Lars & Hirsch, Jan-M (2011). Differential expression of apoptosis, cell cycle regulation and intermediate filament genes in oral squamous cell carcinomas associated with toombak use in Sudan. Anticancer Research.  ISSN 0250-7005.  31(10), s 3345- 3351
  • Sapkota, Dipak; Bruland, Ove; Costea, Daniela Elena; Haugen, Hallvard; Vasstrand, Endre N. & Ibrahim, Salah Osman (2011). S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9. European Journal of Cancer.  ISSN 0959-8049.  47(4), s 600- 610 . doi: 10.1016/j.ejca.2010.10.012
  • Jalouli, Jamshid; Ibrahim, Salah Osman; Mehrotra, Ravi; Jalouli, Miranda M; Sapkota, Dipak; Larsson, Per Anders & Hirsch, Jan-M. (2010). Prevalence of viral (HPV, EBV, HSV) infections in oral submucous fibrosis and oral cancer from India. Acta Oto-Laryngologica.  ISSN 0001-6489.  130(11), s 1306- 1311 . doi: 10.3109/00016481003782041
  • Jalouli, Jamshid; Ibrahim, Salah Osman; Sapkota, Dipak; Jalouli, Miranda M; Vasstrand, Endre N.; Hirsch, Jan M & Larsson, Per Anders (2010). Presence of human papilloma virus, herpes simplex virus and Epstein-Barr virus DNA in oral biopsies from Sudanese patients with regard to toombak use. Journal of Oral Pathology & Medicine.  ISSN 0904-2512.  39(8), s 599- 604 . doi: 10.1111/j.1600-0714.2010.00910.x Vis sammendrag
  • Sapkota, Dipak; Bruland, Ove; Bøe, Olav Egil; Bakeer, Hala; Elgindi, O. A-Aziz; Vasstrand, Endre N. & Ibrahim, Salah Osman (2008). Expression profile of the S100 gene family members in oral squamous cell carcinomas. Journal of Oral Pathology & Medicine.  ISSN 0904-2512.  37(10), s 607- 615 . doi: 10.1111/j.1600-0714.2008.00683.x

Se alle arbeider i Cristin

  • Parajuli, Himalaya; Sapkota, Dipak; Suliman, Salwa; McCormack, Emmet; Johannessen, Anne Christine; Gullberg, Donald & Costea, Daniela Elena (2015). Expression of integrin α-11 by carcinoma associated fibroblasts modulates oral squamous cell carcinoma behaviour.
  • Rajthala, Saroj; Parajuli, Himalaya; Sapkota, Dipak; Gullberg, Donald; Johannessen, Anne Christine & Costea, Daniela Elena (2015). Expression of integrin α-11 by carcinoma associated fibroblasts modulates oral squa- mous cell carcinoma behaviour.
  • Rolland Jacobsen, Martha; Sapkota, Dipak; Johannessen, Anne Christine & Costea, Daniela Elena (2015). Oral premalignant lesions overexpress the collagen-elastin crosslinking enzyme LOXL4.
  • Sapkota, Dipak; Costea, Daniela Elena; himalaya, parajuli; Osman, Tarig Al-Hadi; Bruland, Ove & Johannessen, AC (2014). Role of S100A16 in Differentiation of Oral Squamous Cell Carcinoma.
  • Sapkota, Dipak (2011). S100 Gene Family members in Oral Squamous Cell Carcinomas (OSCCs): Functional Characterization of S100A14 in Proliferation and Invasion of OSCC Derived Cells.
  • Costea, Daniela Elena; Osman, Amani Hamza Ali; Ipatova, A; Sapkota, Dipak; Neppelberg, Evelyn & Lybak, S (2009). Enhanced self-renewal properties of transformed oral epithelial cells after interactions with stromal fibroblasts. Oral Oncology.  ISSN 1368-8375.  s 92- 93 . doi: 10.1016/j.oos.2009.06.194
  • Osman, Amani Hamza Ali; Costea, Daniela Elena; Tsinkalovsky, Oleg; Sapkota, Dipak; Vintermyr, Olav Karsten & Johannessen, Anne Chr. (2009). Phenotypic and functional differences between oral carcinoma-associated fibroblasts and normal oral fibroblasts. Oral Oncology.  ISSN 1368-8375.  s 221- 221 . doi: 10.1016/j.oos.2009.06.586
  • Sapkota, Dipak; Bruland, Ove; Vasstrand, Endre N. & Ibrahim, Salah Osman (2009). Transcriptome signature of the extracellular matrix and adhesion molecules in oral squamous cell carcinomas from sudanese N-nitrosamine rich toombak users. Oral Oncology.  ISSN 1368-8375.  s 99- 100 . doi: 10.1016/j.oos.2009.06.215
  • Sapkota, Dipak; Costea, DE; Bruland, Ove; Vasstrand, Endre N. & Ibrahim, SO (2009). Expression profile of cell adhesion and matrix molecules in oral cancer.
  • Sapkota, Dipak; Bruland, Ove; Vasstrand, Endre N. & Ibrahim, Salah Osman (2008). Down-regulated expression of S100 gene family members in OSCCs.

Se alle arbeider i Cristin

Publisert 5. mai 2017 09:35 - Sist endret 25. mai 2018 13:51

Prosjekter

  • 1. S100A14 and S100A16 proteins in oral cancer: Functional roles, prognostic and therapeutic values
  • 2. miRNA in oral cancer stroma: expression profile, functional roles and prognostic value
  • 3. Development and validation of immunohistochemistry based Quantative Malignancy Index Diagnostic System (qMIDS) for oral cancer diagnostics and personalized therapy
  • 4. Epidemiological study of head and neck cancer in Nepal