Dong Feng Chen
My research focuses on the mechanisms and application of neuroprotective and neuroregenerative approaches for retinal and CNS repair. These works stem from my postdoctoral training in the laboratory of Dr. Susumu Tonegawa, a Nobel Laureate at Massachusetts Institute of Technology. My lab is the first to demonstrate full-length optic nerve regeneration in post born mice, and moreover, discover the molecules that can awaken the "sleeping" retinal progenitor cells to repair the retina. These works hold a promise not only for restoring sight to people with retinal or optic nerve damage or diseases, but similarly to repair spinal cord or brain injuries. My expertise in retinal biology, retinal injury response, and neuroretinal repair and regeneration has contributed critically to the knowledge and design of therapeutics for blind-causing retinal diseases and for overcoming the key barriers to restore vision. Our work was published in Cell, Nature, Science, Neuron, Nature Neuroscience and so forth.
I was elected as a member of Retinal Cell Biology Program Committee at the Association of Research for Vision and Ophthalmology (ARVO) in 2007 and served as the Chair of the committee between 2009 – 2010. I am also the Chair of Women’s Eye Health Organization, an international group founded in the Department of Ophthalmology, Harvard Medical School with a mission to educate the society about eye diseases. I am an Editorial Board Member of Stem Cells, Neural Regeneration Research, and Asia-Pacific Journal of Ophthalmology, and a member of the Scientific Advisory Board of New Jersey Commission on Brain Injury. I have served on many NIH study sections as well as chaired the Eye and ENT study section in the National Nature Science Foundation, China between 2011 – 2012. I was awarded with Visiting Professorship at the New York Eye and Ear Infirmary in 2008 and an RPB Sybil B. Harrington Scholar. I was a recipient of Outstanding Scientific Achievement Award from RP International.
- Pasovic, Lara; Eidet, Jon Roger; Olstad, Ole Kristoffer; Chen, Dong Feng; Lyberg, Torstein & Utheim, Tor Paaske (2017). Impact of Storage Temperature on the Expression of Cell Survival Genes in Cultured ARPE-19 Cells. Current Eye Research. ISSN 0271-3683. 42(1), s 134- 144 . doi: 10.3109/02713683.2016.1145236
- Sehic, Amer; Guo, Shuai; Cho, Kin-Sang; Corroya, Rima Maria; Chen, Dong Feng & Utheim, Tor Paaske (2016). Electrical stimulation as a means for improving vision. American Journal of Pathology. ISSN 0002-9440. 186(11), s 2783- 2797 . doi: 10.1016/j.ajpath.2016.07.017