Trude M Haug

Førsteamanuensis - Institutt for oral biologi
Bilde av Trude M Haug
English version of this page
Telefon +47-22844414
Rom A1.M068
Brukernavn
Besøksadresse Sognsvannsveien 10 Domus Odontologica 0372 OSLO
Postadresse Postboks 1052 Blindern 0316 OSLO
Andre tilknytninger Institutt for biovitenskap

Faglige interesser

Elektrofysiologi, nevroendokrinologi, intracellulær signalisering. Regulering av hypofysehormoner. Gonadotrope cellers mikroanatomi og plastisitet. Spyttkjertelcellers elektrofysiologi.  

 

Metoder

  • Patch-clamp
  • Ca2+-imaging

 

Undervisning

TP1100, OD2100, OD2200

 

Bakgrunn

Dr. Scient 1999 UiO, Cand. Scient. 1996 UiO.

 

Tidligere stillinger

Førsteamanuensis ved Atlantis Medisinske Høgskole 2014-2017, Post-doc/Forsker/Gruppeleder ved Universitetet i Oslo 2002-2014, Post-doc ved UCLA, USA 2000-2001.

 

Samarbeid

DeMiCa, IOB, UiO

Finn-Arne Weltzien, NMBU

CINPLA, Marianne Fyhn, IBV, UiO

Emneord: Fysiologi, Elektrofysiologi, TP1100, OD2100, OD2200

Publikasjoner

  • von Krogh, Kristine; Bjørndal, Gunnveig Toft; Nourizadeh-Lillabadi, Rasoul; Hodne, Kjetil; Ropstad, Erik; Haug, Trude M & Weltzien, Finn-Arne (2017). Sex steroids differentially regulate fshb, lhb and gnrhr expression in Atlantic cod (Gadus morhua). Reproduction.  ISSN 1470-1626.  154(5), s 581- 594 . doi: 10.1530/REP-17-0208
  • Strandabø, Rønnaug; Grønlien, Heidi Kristine; Ager-Wick, Eirill; Nourizadeh-Lillabadi, Rasoul; Hildahl, Jon Paul; Weltzien, Finn-Arne & Haug, Trude M (2016). Identified lhb-expressing cells from medaka (Oryzias latipes) show similar Ca2+-response to all endogenous Gnrh forms, and reveal expression of a novel fourth Gnrh receptor. General and Comparative Endocrinology.  ISSN 0016-6480.  229, s 19- 31 . doi: 10.1016/j.ygcen.2016.02.019
  • Ager-Wick, Eirill; Henkel, Christian W.; Haug, Trude M & Weltzien, Finn-Arne (2014). Using normalization to resolve RNA-seq biases caused by amplification from minimal input. Physiological Genomics.  ISSN 1094-8341.  46(21), s 808- 820 . doi: 10.1152/physiolgenomics.00196.2013
  • Sandvik, Guro Katrine; Hodne, Kjetil; Haug, Trude M; Okubo, Kataaki & Weltzien, Finn-Arne (2014). RFamide peptides in early vertebrate development. Frontiers in Endocrinology.  ISSN 1664-2392.  5:203 . doi: 10.3389/fendo.2014.00203 Fulltekst i vitenarkiv
  • Weltzien, Finn-Arne; Hildahl, Jon Paul; Hodne, Kjetil; Okubo, Kataaki & Haug, Trude M (2014). Embryonic development of gonadotrope cells and gonadotropic hormones - Lessons from model fish. Molecular and Cellular Endocrinology.  ISSN 0303-7207.  385(1-2), s 18- 27 . doi: 10.1016/j.mce.2013.10.016
  • Weltzien, Finn-Arne; Hildahl, Jon Paul; Hodne, Kjetil; Okubo, Kataaki & Haug, Trude M (2014). Embryonic development of gonadotrope cells and gonadotropic hormones - Lessons from model fish. Molecular and Cellular Endocrinology.  ISSN 0303-7207.  385, s 18- 27 . doi: 10.1016/j.mce.2013.10.016
  • Hildahl, Jon Paul; Taranger, Geir Lasse; Norberg, Birgitta; Haug, Trude M & Weltzien, Finn-Arne (2013). Differential regulation of GnRH ligand and receptor genes in the brain and pituitary of Atlantic cod exposed to different photoperiod. General and Comparative Endocrinology.  ISSN 0016-6480.  180, s 7- 14 . doi: 10.1016/j.ygcen.2012.09.025
  • Hodne, Kjetil; Strandabø, Rønnaug; von Krogh, Kristine; Nourizadeh-Lillabadi, Rasoul; Sand, Olav; Weltzien, Finn-Arne & Haug, Trude M (2013). Electrophysiological differences between fshb- and lhb-expresing gonadotropes in primary culture. Endocrinology.  ISSN 0013-7227.  154(9), s 3319- 3330 . doi: 10.1210/en.2013-1164
  • Mobråten, Kaia; Haug, Trude M; Kleiveland, Charlotte Ramstad & Lea, Tor Erling (2013). Omega-3 and omega-6 PUFAs induce the same GPR120-mediated signalling events, but with different kinetics and intensity in Caco-2 cells . Lipids in Health and Disease.  ISSN 1476-511X.  12 . doi: 10.1186/1476-511X-12-101
  • Sand, Sverre; Nissen-Meyer, Jon; Sand, Olav & Haug, Trude M (2013). Plantaricin A, a cationic peptide produced by Lactobacillus plantarum, permeabilizes eukaryotic cell membranes by a mechanism dependent on negative surface charge linked to glycosylated membrane proteins. Biochimica et Biophysica Acta - Biomembranes.  ISSN 0005-2736.  1828(2), s 249- 259 . doi: 10.1016/j.bbamem.2012.11.001
  • Strandabø, Rønnaug; Hodne, Kjetil; Ager-Wick, Eirill; Sand, Olav; Weltzien, Finn-Arne & Haug, Trude M (2013). Signal transduction involved in GnRH2-stimulation of identified LH-producing gonadotropes from lhb-GFP transgenic medaka (Oryzias latipes). Molecular and Cellular Endocrinology.  ISSN 0303-7207.  372(1-2), s 128- 139 . doi: 10.1016/j.mce.2013.03.022
  • Hildahl, Jon Paul; Sandvik, Guro Katrine; Lifjeld, Rikke; Hodne, Kjetil; Nagahama, Y; Haug, Trude M; Okubo, Kataaki & Weltzien, Finn-Arne (2012). Developmental Tracing of Luteinizing Hormone b-Subunit Gene Expression Using Green Fluorescent Protein Transgenic Medaka (Oryzias latipes) Reveals a Putative Novel Developmental Function. Developmental Dynamics.  ISSN 1058-8388.  241(11), s 1665- 1677 . doi: 10.1002/dvdy.23860
  • Hodne, Kjetil; von Krogh, Kristine; Weltzien, Finn-Arne; Sand, Olav & Haug, Trude M (2012). Optimized conditions for primary culture of pituitary cells from the Atlantic cod (Gadus morhua). The importance of osmolality, pCO(2), and pH. General and Comparative Endocrinology.  ISSN 0016-6480.  178(2), s 206- 215 . doi: 10.1016/j.ygcen.2012.06.005
  • Hildahl, Jon; Sandvik, Guro Katrine; Edvardsen, Rolf; Fagernes, Cathrine Elisabeth; Norberg, Birgitta; Haug, Trude M & Weltzien, Finn-Arne (2011). Identification and gene expression analysis of three GnRH genes in female Atlantic cod during puberty provides insight into GnRH variant gene loss in fish. General and Comparative Endocrinology.  ISSN 0016-6480.  172(3), s 458- 467 . doi: 10.1016/j.ygcen.2011.04.010
  • Hildahl, Jon; Sandvik, Guro Katrine; Edvardsen, Rolf; Norberg, Birgitta; Haug, Trude M & Weltzien, Finn-Arne (2011). Four gonadotropin releasing hormone receptor genes in Atlantic cod are differentially expressed in the brain and pituitary during puberty. General and Comparative Endocrinology.  ISSN 0016-6480.  173(2), s 333- 345 . doi: 10.1016/j.ygcen.2011.06.002
  • Andersland, Kristin; Jølle, Guro Five; Sand, Olav & Haug, Trude M (2010). Peptide Pheromone Plantaricin A Produced by Lactobacillus plantarum Permeabilizes Liver and Kidney Cells. Journal of Membrane Biology.  ISSN 0022-2631.  235(2), s 121- 129 . doi: 10.1007/s00232-010-9263-4
  • Haug, Trude M; Sand, Sverre; Sand, Olav; Phung, Danh; Granum, Per Einar & Hardy, Simon P. (2010). Formation of Very Large Conductance Channels by Bacillus cereus Nhe in Vero and GH(4) Cells Identifies NheA plus B as the Inherent Pore-Forming Structure. Journal of Membrane Biology.  ISSN 0022-2631.  237(1), s 1- 11 . doi: 10.1007/s00232-010-9298-6
  • Haug, Trude Marie; Sand, Sverre; Sand, Olav; Phung, Danh; Granum, Per Einar & Hardy, Simon P. (2010). Formation of Very Large Conductance Channels by Bacillus cereus Nhe in Vero and GH4 Cells Identifies NheA + B as the Inherent Pore-Forming Structure. Journal of Membrane Biology.  ISSN 0022-2631.  237, s 1- 11
  • Hodne, Kjetil; Haug, Trude M & Weltzien, Finn-Arne (2010). Single-cell qPCR on dispersed primary pituitary cells -an optimized protocol. BMC Molecular Biology.  ISSN 1471-2199.  11 . doi: 10.1186/1471-2199-11-82
  • Haug, Trude M; Hodne, Kjetil; Weltzien, Finn-Arne & Sand, Olav (2007). Electrophysiological properties of pituitary cells in primary culture from Atlantic cod (Gadus morhua). Neuroendocrinology.  ISSN 0028-3835.  86, s 38- 47 . doi: 10.1159/000103867
  • Sand, Sverre; Haug, Trude M; Nissen-Meyer, Jon & Sand, Olav (2007). The bacterial peptide pheromone plantaricin a permeabilizes cancerous, but not normal, rat pituitary cells and differentiates between the outer and inner membrane leaflet. Journal of Membrane Biology.  ISSN 0022-2631.  216(2-3), s 61- 71 . doi: 10.1007/s00232-007-9030-3
  • Hafting, Torkel; Haug, Trude M; Ellefsen, Stian & Sand, Olav (2006). Hypotonic stress activates BK channels in clonal kidney cells via purinergic receptors, presumably of the P2Y1 subtype. Acta Physiologica.  ISSN 1748-1708.  188(1), s 21- 32 . doi: 10.1111/j.1748-1716.2006.01601
  • Mørk, Halvor Kjeang; Haug, Trude M & Sand, Olav (2005). Contribution of different Ca-activated K channels to the first phase of the response to TRH in clonal rat anterior pituitary cells. Acta Physiologica Scandinavica.  ISSN 0001-6772.  184(2), s 141- 150 . doi: 10.1111/j.1365-201X.2005.01441
  • Haug, Trude M (2004). Regulation of K+ flow by a ring of negative charges in the outer pore of the BKCa channels. Part II: Ionic and gating currents. The Journal of General Physiology.  ISSN 0022-1295.  124, s 185- 197
  • Haug, Trude M; Sigg, D; Ciani, S; Toro, L; Stefani, E & Olcese, R (2004). Regulation of K+ flow by a ring of negative charges in the outer pore of the BKCa channels. Part I: Aspartate 292 modulates K+ conductance by external surface charge effect. The Journal of General Physiology.  ISSN 0022-1295.  124, s 173- 184
  • Haug, Trude M; Hafting, Torkel & Sand, Olav (2004). Inhibition of BK channels contributes to the second phase of the response to TRH in clonal rat anterior pituitary cells. Acta Physiologica Scandinavica.  ISSN 0001-6772.  180, s 347- 357
  • Haug, Trude M & Storm, Johan Fredrik (2000). Protein kinase A mediates the modulation of the slow Ca2+-dependent K+ current, IsAHP, by the neuropeptides CRF, VIP and CGRP in hippocampal pyramidal neurons. Journal of Neurophysiology.  ISSN 0022-3077.  83, s 2071- 2079
  • Gribble, Fiona M; Tucker, SJ; Haug, Trude M & Ashcroft, Fran M (1998). MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  95, s 7185- 7190
  • Haug, Trude M (1998). Molecular determinants of KATP channel inhibition by ATP. EMBO Journal.  ISSN 0261-4189.  17, s 3290- 3296
  • Pedarzani, P.; Haug, Trude M; Storm, Johan Fredrik & Stühmer, W. (1998). Modulation of the slow Ca2+-activated K+ current sIAHP by a phosphatase/kinase balance under basal conditions in rat CA1 pyramidal neurons. Journal of Neurophysiology.  ISSN 0022-3077.  79(6), s 3252- 3256
  • Haug, Trude M & Sand, Olav (1997). BK channels in intact clonal rat pituitary cells are activated by physiological elevations of the cytosolic Ca2+ concentration at the normal resting potential. Acta Physiologica Scandinavica.  ISSN 0001-6772.  161, s 227- 237

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  • Mobråten, Kaia; Haug, Trude M; Kleiveland, Charlotte Ramstad & Lea, Tor Erling (2013). Omega-3 and omega-6 PUFAs both activated GPR120 in Caco2 cells.
  • Sand, Sverre L.; Nissen-Meyer, Jon; Sand, Olav & Haug, Trude M (2011). The cationic peptide plantaricin A produced by Lactobacillus plantarum permeabilizes eukaryotic cell membranes by a mechanism dependent on negative surface charge linked to glycosylated membrane proteins. Acta Physiologica.  ISSN 1748-1708.  202, s P56
  • Haug, Trude M; Sand, Sverre L.; Phung, Danh; Hardy, Simpn P. & Sand, Olav (2009). The Bacillus cereus Nhe enterotoxin forms gigantic channels in cell membranes. Acta Physiologica.  ISSN 1748-1708.  196, s P30
  • Andersland, Kristin; Johansen, Guro Five; Haug, Trude M & Sand, Olav (2008). THE ANTIMICROBIAL PEPTIDE PLANTARICIN A PERMEABILIZES LIVER AND KIDNEY CELLS. Acta Physiologica.  ISSN 1748-1708.  193, s P17
  • Haug, Trude M; Hodne, Kjetil; Weltzien, Finn-Arne & Sand, Olav (2007). Signaling properties of teleost gonadotropes with a first study from atlantic cod. Acta Physiologica.  ISSN 1748-1708.  190, s 504
  • Haug, Trude M; Hodne, Kjetil; Weltzien, Finn-Arne & Sand, Olav (2006). Electrophysiological properties of pituitary cells in primary cultures from atlantic cod (Gadus morhua). Acta Physiologica.  ISSN 1748-1708.  187, s P23
  • Kristiansen, Per Eugen; Sand, Sverre; Haug, Trude M; Sand, Olav; Fimland, Gunnar; Zhao, Hongxia; Jutila, Arimatti; Bose, Shambhunath; Kinnunen, Paavo K.J. & Nissen-Meyer, Jon (2006). Structure and Mode of Action of the Membrane-Permeabilizing Antimicrobial Peptide Pheromone Plantaricin A.
  • Sand, Sverre L.; Haug, Trude M; Nissen-Meyer, Jon & Sand, Olav (2006). Clonal rat anterior pituitary cells (GH4 cells) are permeabilized by plantaricin A, a peptide pheromone produced by Lactobacillus plantarum. SFN Abstract Viewer/Itinerary Planner.
  • Sand, Sverre Larsstuvold; Haug, Trude M; Fimland, Gunnar; Nissen-Meyer, Jon & Sand, Olav (2006). Membrane-permeabilizing effects of the bacterial peptide Plantaricin A on rat anterior pituitary cells. Acta Physiologica.  ISSN 1748-1708.  187, s P11
  • Sand, Olav; Haug, Trude M & Mørk, Halvor (2005). Electrophysiological properties of anterior pituitary cells. Acta Physiologica Scandinavica.  ISSN 0001-6772.  183, s A402
  • Haug, Trude M; Hafting, Torkel & Sand, Olav (2004). Contribution of BK channels to the resting conductance and the second phase of the response to TRH in anterior pituitary cells (GH4C1cells). Acta Physiologica Scandinavica.  ISSN 0001-6772.  181, s A140
  • Mørk, Halvor; Haug, Trude M & Sand, Olav (2004). Contribution of different Ca2+-activated K+-channels to the first phase of the TRH response in clonal anterior pituitary cells (GH4 cells). Acta Physiologica Scandinavica.  ISSN 0001-6772.  181, s A140
  • Haug, Trude M; Ciani, Sergio; Toro, Ligia; Stefani, Enrico & Olcese, Riccardo (2003). Neutralization of the aspartate in the GYGD pore sequence affects gating properties in BKCa channels.
  • Haug, Trude M; Hafting-Fyhn, Torkel & Sand, Olav (2003). Contribution of BK channels to the second phase of the response to TRH in anterior pituitary cells (GH4 cells). SFN Abstract Viewer/Itinerary Planner.
  • Haug, Trude M; Olcese, Riccardo; Ciani, Sergio; Toro, Ligia & Stefani, Enrico (2002). Regulation of inward potassium flow by a negative residue in the outer vestibule of the MaxiK channel pore.
  • Olcese, Riccardo; Zhu, Ning; Haug, Trude M; Toro, Ligia & Stefani, Enrico (2002). Conformational changes in BK(Ca) channel during channel opening and closing revealed by optical methods.
  • Stefani, Enrico; Haug, Trude M; Ciani, Sergio; Toro, Ligia & Olcese, Riccardo (2002). Conduction of K ions through BKCa channels is enhanced by a negatively charged residue near the pore (D292).
  • Haug, Trude M; Olcese, Riccardo; Zhu, Ning; Toro, Ligia & Stefani, Enrico (2001). Reduced Ca2+-sensitivity in the D292N mutant of hSlo potassium channel pore.
  • Olcese, Riccardo; Zhu, Ning; Haug, Trude M; Toro, Ligia & Stefani, Enrico (2001). Voltage dependent conformational changes in MaxiK channels assessed by fluorescent labeling.
  • Storm, Johan Fredrik; Pedarzani, P. & Haug, Trude M (2000). Modulation of K+ channels in hippocampal neurons: transmitters acting via cyclic AMP enhance the excitability through kinase-dependent and -independent modulation of AHP- and h-channels.
  • Haug, Trude M & Storm, Johan Frederik (1999). Ca2+ -activated and ATP-sensitive potassium channels in endocrine cells and neurons.
  • Haug, Trude M & Storm, Johan Fredrik (1998). Peptidergic modulation via protein kinase A of the slow Ca2+-dependent K+ current IAHP in hippocampal pyramidal cells.
  • Haug, Trude M & Sand, Olav (1997). BK-channels in cell-attached patches of clonal pituitary cells (GH4 cells). Abstracts - Society for Neuroscience.  ISSN 0190-5295.  23(2), s 1481
  • Haug, Trude M & Sand, Olav (1996). Activation of BK-channels in intact clonal pituitary cells. Acta Physiologica Scandinavica.  ISSN 0001-6772.  157, s 51A

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Publisert 5. apr. 2017 10:44 - Sist endret 16. mai 2017 11:05