Era4Health - Pragmatic Comparative-Effectiveness Trials in Non-communicable Diseases

Era4Health has announced a call for transnational research projects with randomized, interventional and pragmatic comparative-effectiveness multi-country investigator-initiated clinical studies.

Link to the call

Era4Health

The ERA4Health Partnership aims to coordinate funding organizations across Europe to address public health needs through collaborative research, and it is preparing to launch its first joint transnational call for clinical studies on comparative-effectiveness trials in non-communicable diseases.

Scope of the call

Proposals should address all the 4 following points: 

  1. Be a pragmatic comparative effectiveness trials, designed as randomised interventional trials. 
  2. Compare the use of currently approved healthcare interventions either to each other or to the current standard of care. 
  3. Consider healthcare interventions which could include but would not be limited to: diagnostic, screening, prevention and treatment interventions. The interventions can be pharmacological as well as non-pharmacological procedures like nutrition and/or lifestyle interventions, surgery, prognosis methods, use of medical devices, eHealth and digital interventions and other health interventions. 
  4. Interventions shall have high public relevance only in the fields of these specific diseases or conditions (that are of equal importance): 
  • Cardiovascular diseases
  • Metabolic disorders
  • Nutrition and lifestyle-related diseases
  • Non-communicable respiratory diseases

Projects should primarily address at least one of the diseases/conditions, but can also include several of them and/or other related comorbidities.

Beyond the research topics, there are further requirements and recommendations to the proposals, please see link to the call. Further information here.

Eligibility

This type of call normally require a consortium with partners from minimum three of the countries participating in the call (se announcement for the list of participating countries). 

Available funding

Project partners will be funded by their relevant national/regional funding organisation. Norwegian participants are funded by the Research Council of Norway. Eligible costs and funding rules vary between the respective funding organisations.

The Research Council of Norway's funding for Norwegian participants totals to 10 mNOK. 

Timeline

21 October 2024 Pre-announcement of the EffectTrial call
20 November, 2024 EffectTrial call published
27 November 2024 Webinar Info day recording
28 January, 2025 Deadline for pre-proposal submission
15 April, 2025 Communication of the results of the pre-proposal
assessment (invitation for full proposal)
17 June, 2025 Deadline for full proposal submission
25 August - 5 Sept, 2025 Rebuttal stage
End-October 2025 Communication of the funding decisions to the applicants
January – May 2026 Expected project start (subject to national procedures)
Published Dec. 26, 2024 9:08 PM - Last modified Dec. 26, 2024 9:25 PM