Alejandro Barrantes Bautista

• Weber, Florian; Morais Dornelas Figueira, Louise; Hafiane, Nora; Zaytseva-Zotova, Daria; Barrantes Bautista, Alejandro & Petersen, Fernanda Cristina [Vis alle 7 forfattere av denne artikkelen] (2022). Can polyphenolic surface modifications prevent fungal colonization of titanium dental implants? Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 219. doi: 10.1016/j.colsurfb.2022.112813. Fulltekst i vitenarkiv
• Hassan, Hafiz Wajahat; Rahmati, Maryam; Barrantes Bautista, Alejandro; Haugen, Håvard Jostein & Mirtaheri, Peyman (2022). In Vitro Monitoring of Magnesium-Based Implants Degradation by Surface Analysis and Optical Spectroscopy. International Journal of Molecular Sciences. ISSN 1661-6596. 23(11). doi: 10.3390/ijms23116099. Fulltekst i vitenarkiv Vis sammendrag

  Magnesium (Mg)-based degradable alloys have attracted substantial attention for tissue engineering applications due to their biodegradability and potential for avoiding secondary removal surgeries. However, insufficient data in the existing literature regarding Mg’s corrosion and gas formation after implantation have delayed its wide clinical application. Since the surface properties of degradable materials constantly change after contact with body fluid, monitoring the behavior of Mg in phantoms or buffer solutions could provide some information about its physicochemical surface changes over time. Through surface analysis and spectroscopic analysis, we aimed to investigate the structural and functional properties of degradable disks. Since bubble formation may lead to inflammation and change pH, monitoring components related to acidosis near the cells is essential. To study the bubble formation in cell culture media, we used a newly developed Mg alloy (based on Mg, Zinc and Calcium), pure Mg and commercially available grade 2 Titanium (Ti) disks in Dulbecco's Modified Eagle Medium (DMEM) solution to observe their behavior over ten days of immersion. Using surface analysis, and the information from near-infrared spectroscopy (NIRS), we concluded conditions associated with the medical risks of Mg alloy disintegration. NIRS is used to investigate the degradation behaviour of Mg-based disks in the cell culture media, which is correlated with the surface analysis where possible.

• Vilaça, Adriana; Domingues, Rui M. A,; Tiainen, Hanna; Mendes, Bárbara B.; Barrantes Bautista, Alejandro & Reis, Rui L. [Vis alle 8 forfattere av denne artikkelen] (2021). Multifunctional surfaces for improving soft tissue integration. Advanced Healthcare Materials. ISSN 2192-2640. doi: 10.1002/adhm.202001985. Fulltekst i vitenarkiv
• Borie, Manon; Lecloux, Geoffrey; Bosshardt, Dieter D.; Barrantes Bautista, Alejandro; Haugen, Håvard Jostein & Lambert, France [Vis alle 7 forfattere av denne artikkelen] (2020). Peri-Implant Soft Tissue Integration in Humans – Influence of Materials: A study protocol for a randomised controlled trial and a pilot study results. Contemporary Clinical Trials Communications. ISSN 2451-8654. doi: 10.1016/j.conctc.2020.100643. Fulltekst i vitenarkiv Vis sammendrag

  Background : Recently, there has been a growing interest in mucointegration as the formation of an early and long-standing soft tissue barrier seems essential for both the initial healing and long-term implant survival. Aim: To develop an experimental method to characterize the mucointegration of different transgingival materials (titanium (Ti), polyetheretherketone (PEEK), polymethylmethacrylate (PMMA), zirconia (Zi), polymer infiltrated ceramic network (PICN), cobalt-chrome (Co-Cr), and lithium disilicate (LD)) in a human model. Methods / Design : The study is designed as a multi-part randomized controlled clinical trial. Ninety bone level Straumann implants will randomly receive an experimental, custom-made abutment to allow for the removal of the abutment together with the surrounding soft tissues using a punch biopsy device at 8 weeks of healing (10 per material). The specimens will be further processed for non‐decalcified histology, followed by histomorphometric analysis. The same protocol will be used for additional 90 implants-abutments, but during harvesting, soft tissues will be separated from the abutment and processed for immunohistochemistry in order to study tissue inflammation and vascularization, while the abutments will undergo SEM analysis. Additionally, in vitro analyses, including SEM and profilometry, will be performed in order to characterize surface topography of all experimental materials. Conclusion : The limited number of pilot samples presented herein indicate that the use of custommade abutments in humans is a reproducible method to study peri-implant soft tissue integration. This further intensifies the rationale to compare different abutment materials, used as transgingival components in daily practice, under the same conditions.

• Weber, Florian; Liao, Wei-Chih; Barrantes Bautista, Alejandro; Edèn, Mattias & Tiainen, Hanna (2019). Silicate‐Phenolic Networks: Coordination Mediated Deposition of Bioinspired Tannic Acid Coatings. Chemistry - A European Journal. ISSN 0947-6539. 25(42), s. 9870–9874. doi: 10.1002/chem.201902358. Fulltekst i vitenarkiv
• Geissler, Sebastian; Gomez-Florit, Manuel; Wiedmer, David; Barrantes Bautista, Alejandro; Petersen, Fernanda Cristina & Tiainen, Hanna (2019). In vitro performance of bioinspired phenolic nanocoatings for endosseous implant applications. ACS Biomaterials Science and Engineering. ISSN 2373-9878. 5(7), s. 3340–3351. doi: 10.1021/acsbiomaterials.9b00566. Fulltekst i vitenarkiv
• Weber, Florian; Barrantes Bautista, Alejandro & Tiainen, Hanna (2019). Silicic acid mediated formation of tannic acid nanocoatings. Langmuir. ISSN 0743-7463. 35, s. 3327–3336. doi: 10.1021/acs.langmuir.8b04208. Fulltekst i vitenarkiv
• Weber, Florian & Barrantes Bautista, Alejandro (2017). Real-time formation of salivary films onto polymeric materials for dental applications: Differences between unstimulated and stimulated saliva. Colloids and Surfaces B: Biointerfaces. ISSN 0927-7765. 154, s. 203–209. doi: 10.1016/j.colsurfb.2017.03.022. Fulltekst i vitenarkiv
• Barrantes Bautista, Alejandro; Wengenroth, Jonas; Arnebrant, Thomas & Haugen, Håvard Jostein (2017). Poly-L-lysine/heparin multilayer coatings prevent blood protein adsorption. Journal of Colloid and Interface Science. ISSN 0021-9797. 485, s. 288–295. doi: 10.1016/j.jcis.2016.09.046. Fulltekst i vitenarkiv
• Geissler, Sebastian; Barrantes, Alejandro; Tengvall, Pentti; Messersmith, Phillip B. & Tiainen, Hanna (2016). Deposition kinetics of bioinspired phenolic coatings on titanium surfaces . Langmuir. ISSN 0743-7463. 32, s. 8050–8060. doi: 10.1021/acs.langmuir.6b01959. Fulltekst i vitenarkiv

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• Weber, Florian; Barrantes Bautista, Alejandro & Tiainen, Hanna (2021). Antioxidant polyphenolic implant coatings for improved wound healing.
• Weber, Florian; Barrantes Bautista, Alejandro & Tiainen, Hanna (2021). Can plant polyphenol inspired surface modifications improve tissue integration of titanium implants?
• Weber, Florian; Barrantes Bautista, Alejandro & Tiainen, Hanna (2019). Plant polyphenolic inspired anti-inflammatory and anti-bacterial surface modifications for dental implants.
• Weber, Florian; Liao, Wei-Chih; Barrantes Bautista, Alejandro; Edèn, Mattias & Tiainen, Hanna (2019). Silicic acid mediated formation of tannic acid coatings.
• Weber, Florian; Tiainen, Hanna & Barrantes Bautista, Alejandro (2018). pH dependent coating formation of tannic acid on titanium surfaces.
• Weber, Florian; Tiainen, Hanna & Barrantes Bautista, Alejandro (2017). pH dependent coating formation of tannic acid on titanium surfaces.
• Geissler, Sebastian; Gomez-Florit, Manuel; Barrantes, Alejandro & Tiainen, Hanna (2016). Deposition kinetics of bioinspired polyphenol nanocoatings and their effect on osteogenic differentiation on titanium surfaces.
• Geissler, Sebastian; Barrantes, Alejandro; Tengvall, Pentti & Tiainen, Hanna (2016). Coating kinetics of bioinspired phenolic films on titanium surfaces.
• Geissler, Sebastian; Barrantes, Alejandro; Tengvall, Pentti & Tiainen, Hanna (2016). Reaction kinetics of bioinspired phenolic coatings on titanium surfaces.

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