Sudhanshu Shekhar

Bilde av Sudhanshu Shekhar
English version of this page
Telefon +47 22840327
Brukernavn
Besøksadresse Sognsvannsveien 10 Domus Odontologica 0372 OSLO
Postadresse Postboks 1052 Blindern 0316 OSLO

Dr Sudhanshu Shekhar is a Scientist in Infection and Immunity at the Institute of Oral Biology, University of Oslo, Norway. His research interests include: 1) exploiting the oral commensal Streptococcus mitis to develop novel prophylactic strategies against Streptococcus pneumoniae infections; and 2) the impact of antibiotics and probiotics on infant immunity and microbiota. He received an MSc in Integrated Immunology from the University of Oxford, England, and a PhD in Infection and Immunity from the University of Manitoba, Canada. Subsequently, he worked as a postdoctoral research fellow at the Institute of Oral Biology, University of Oslo, studying protective immunity to pneumococcal infections induced by oral commensals.  Of note, he also holds a DVM in Veterinary Medicine and a BSc (Hons) in Biology.

Emneord: Infeksjon og immunitet, lungeimmunologi, vaksinologi, medfødt lymfosytt cytometri, Celledyrking, histopatologi

Publikasjoner

  • Shekhar, Sudhanshu & Yang, Xi (2020). Pulmonary CD103+ dendritic cells: key regulators of immunity against infection. Cellular & Molecular Immunology.  ISSN 1672-7681. . doi: 10.1038/s41423-020-0397-8
  • Khan, Rabia; Petersen, Fernanda Cristina & Shekhar, Sudhanshu (2019). Commensal bacteria: An emerging player in defense against respiratory pathogens. Frontiers in Immunology.  ISSN 1664-3224.  10:1203(MAY), s 1- 9 . doi: 10.3389/fimmu.2019.01203
  • Shekhar, Sudhanshu; Khan, Rabia; Khan, Ata Ul Razzaq & Petersen, Fernanda Cristina (2019). Mouse IgG2a Antibodies Specific for the Commensal Streptococcus mitis Show Stronger Cross-Reactivity with Streptococcus pneumoniae than IgG1 Antibodies. Journal of Immunology Research.  ISSN 2314-8861.  2019 . doi: 10.1155/2019/7906724
  • Shekhar, Sudhanshu; Khan, Rabia; Schenck, Karl & Petersen, Fernanda Cristina (2019). Intranasal Immunization with the Commensal Streptococcus mitis Confers Protective Immunity against Pneumococcal Lung Infection. Applied and Environmental Microbiology.  ISSN 0099-2240.  85(6) . doi: 10.1128/AEM.02235-18
  • Shekhar, Sudhanshu; Khan, Rabia; Ferreira, Daniela M.; Mitsi, Elena; German, Esther; Rørvik, Gro Herredsvela; Berild, Dag; Schenck, Karl; Kwon, Keehwan & Petersen, Fernanda Cristina (2018). Antibodies reactive to commensal Streptococcus mitis show cross-reactivity with virulent Streptococcus pneumoniae serotypes. Frontiers in Immunology.  ISSN 1664-3224.  9:747, s 1- 10 . doi: 10.3389/fimmu.2018.00747 Fulltekst i vitenarkiv. Vis sammendrag
  • Shekhar, Sudhanshu; Peng, Ying; Wang, Shuhe & Yang, Xi (2018). CD103+ lung dendritic cells (LDCs) induce stronger Th1/Th17 immunity to a bacterial lung infection than CD11bhi LDCs. Cellular & Molecular Immunology.  ISSN 1672-7681. . doi: 10.1038/cmi.2016.68
  • Shekhar, Sudhanshu; Schenck, Karl & Petersen, Fernanda Cristina (2018). Exploring Host–Commensal Interactions in the Respiratory Tract. Frontiers in Immunology.  ISSN 1664-3224.  8, s 1- 7 . doi: 10.3389/fimmu.2017.01971 Fulltekst i vitenarkiv. Vis sammendrag
  • Junges, Roger; Salvadori, Gabriela; Shekhar, Sudhanshu; Åmdal, Heidi Aarø; Periselneris, Jimstan; Chen, Tsute; Brown, Jeremy S. & Petersen, Fernanda Cristina (2017). A quorum-sensing system that regulates Streptococcus pneumoniae biofilm formation and surface polysaccharide production. mSphere.  ISSN 2379-5042.  2(5), s 1- 18 . doi: 10.1128/mSphere.00324-17 Fulltekst i vitenarkiv.
  • Jayappa, Kallesh Danappa; Ao, Zhujun; Wang, Xiaoxia; Mouland, Andrew J.; Shekhar, Sudhanshu; Yang, Xi & Yao, Xiaojian (2015). Human immunodeficiency virus type 1 employs the cellular dynein light chain 1 protein for reverse transcription through interaction with its integrase protei. Journal of Virology.  ISSN 0022-538X.
  • Peng, Ying; Gao, Xiaoling; Yang, Jie; Shekhar, Sudhanshu; Wang, Shuhe; Fan, Yijun & Yang, Xi (2015). Chlamydial lung infection induces transient IL-9 production which is redundant for host defense against primary infection. PLOS ONE.  ISSN 1932-6203.
  • Shekhar, Sudhanshu; Joyee, Antony George; Gao, Xiaoling; Peng, Ying; Wang, Shuhe; Yang, Jie & Yang, Xi (2015). Invariant Natural Killer T Cells Promote T Cell Immunity by Modulating the Function of Lung Dendritic Cells during Chlamydia pneumoniae Infection. Journal of Innate Immunity.  ISSN 1662-811X.
  • Shekhar, Sudhanshu; Joyee, Antony George & Yang, Xi (2015). Dynamics of NKT-Cell Responses to Chlamydial Infection. Frontiers in Immunology.  ISSN 1664-3224.
  • Shekhar, Sudhanshu & Yang, Xi (2015). Natural killer cells in host defense against veterinary pathogens. Veterinary Immunology and Immunopathology.  ISSN 0165-2427.
  • Shekhar, Sudhanshu; ying, Peng; Gao, Xiaoling; Joyee, Antony George; Wang, Shuhe; Bai, Hong; Zhao, Lei; Yang, Jie & Yang, Xi (2015). NK cells modulate the lung dendritic cell-mediated Th1/Th17 immunity during intracellular bacterial infection. European Journal of Immunology.  ISSN 0014-2980.
  • Peng, Ying; Gao, Xiaoling; Yang, Jie; Shekhar, Sudhanshu; Wang, Shuhe; Fan, Yijun; Zhao, Weiming & Yang, Xi (2014). Interleukin-22 promotes T helper 1 (Th1)/Th17 immunity in chlamydial lung infection.. Molecular medicine (Cambridge, Mass. Print).  ISSN 1076-1551.
  • Shekhar, Sudhanshu; Joyee, Antony George & Yang, Xi (2014). Invariant natural killer T cells: boon or bane in immunity to intracellular bacterial infections?. Journal of Innate Immunity.  ISSN 1662-811X.
  • Peng, Ying; Zhao, Lei; Shekhar, Sudhanshu; Liu, Lu; Wang, Hong; Chen, Qiang; Gao, Xiaoling; Yang, Xi & Zhao, Weiming (2012). The glycolipid exoantigen derived from Chlamydia muridarum activates invariant natural killer T cells.. Cellular & Molecular Immunology.  ISSN 1672-7681.
  • Shekhar, Sudhanshu; Milling, Simon; Jenkins, Chris & MacPherson, Gordon (2012). Identification and phenotypic characterization of γδ T cells in rat lymph.. Research in Veterinary Science.  ISSN 0034-5288.
  • Shekhar, Sudhanshu; Milling, Simon & Yang, Xi (2012). Migration of γδ T cells in steady-state conditions.. Veterinary Immunology and Immunopathology.  ISSN 0165-2427.
  • Shekhar, Sudhanshu & Yang, Xi (2012). The darker side of follicular helper T cells: from autoimmunity to immunodeficiency.. Cellular & Molecular Immunology.  ISSN 1672-7681.

Se alle arbeider i Cristin

  • Shekhar, Sudhanshu (2020). Impact of Antibiotics on Microbiome and Immune Defense in Infants.
  • Shekhar, Sudhanshu (2020). Impact of antibiotics on the infant microbiota and immunity.
  • Shekhar, Sudhanshu (2019). Impact of antibiotics on microbiome and immunity in infant mice.
  • Shekhar, Sudhanshu (2019). Inactivated Rabies Virus-Based Ebola Vaccine Preserved by Vaporization Is Heat-Stable and Immunogenic Against Ebola and Protects Against Rabies Challenge.
  • Shekhar, Sudhanshu (2019). Mobilizing oral commensals to fight Streptococcus pneumoniae infection.
  • Shekhar, Sudhanshu; Khan, Rabia; Schenck, Karl & Petersen, Fernanda Cristina (2019). Intranasal immunization with the oral commensal Streptococcus mitis induces protection against Streptococcus pneumoniae infection.
  • Shekhar, Sudhanshu; Petersen, Fernanda Cristina & Yang, Xi (2019). Editorial: Understanding and Exploiting Host-Commensal Interactions to Combat Pathogens. Frontiers in Immunology.  ISSN 1664-3224. . doi: 10.3389/fimmu.2019.02645
  • Shekhar, Sudhanshu (2018). Commensal Streptococcus mitis as a vaccine against pneumococcal diseases.
  • Shekhar, Sudhanshu (2018). Harnessing commensal bacteria to combat pneumococcal infections.
  • Shekhar, Sudhanshu (2018). Mobilizing beneficial microbes to provide protection against pneumococcal infections.
  • Shekhar, Sudhanshu; Rabia, Khan; Karl, Schenck & Fernanda, Petersen (2018). Intranasal immunization with commensal Streptococcus mitis confers protective immunity against virulent pneumococcal lung infection.
  • Guan, Qingdong; Gao, Xiaoling; Wang, Jun-hui; Sun, Yu & Shekhar, Sudhanshu (2017). Cytokines in Autoimmune Disease. Mediators of Inflammation.  ISSN 0962-9351.  2017:5089815, s 1- 2 . doi: 10.1155/2017/5089815
  • Shekhar, Sudhanshu (2017). Antibodies specific to Streptococcus mitis show cross-reactivity with a range of virulent S. pneumoniae serotypes.
  • Shekhar, Sudhanshu (2017). Antibodies specific to Streptococcus mitis show cross-reactivity with a range of virulent S. pneumoniae serotypes.
  • Shekhar, Sudhanshu (2017). Chairman.
  • Shekhar, Sudhanshu (2017). Commensal Streptococcus mitis: A Potential Tool to Combat Virulent Streptococcus pneumoniae Serotypes.
  • Shekhar, Sudhanshu (2017). Host-Commensal Interactions.
  • Shekhar, Sudhanshu (2017). Natural polyreactive IgA antibodies coat the intestinal microbiota.
  • Shekhar, Sudhanshu; Khan, Rabia; Daniela, Ferreira; Karl, Schenck; Keehwan, Kwon & Fernanda, Petersen (2017). Antibodies specific to Streptococcus mitis show cross-reactivity with a range of virulent S. pneumoniae serotypes.
  • Shekhar, Sudhanshu; Khan, Rabia; Ferreira, Daniela; Schenck, Karl; Kwon, Keehwan & Petersen, Fernanda Cristina (2017). Streptococcus mitis-specific antibodies show cross-reactivity with a range of virulent Streptococcus pneumoniae serotypes.
  • Shekhar, Sudhanshu; Khan, Rabia; Ferreira, Daniela; Schenck, Karl; Kwon, Keehwan & Petersen, Fernanda Cristina (2017). Streptococcus mitis-specific antibodies show cross-reactivity with a range of virulent Streptococcus pneumoniae serotypes.
  • Khan, Rabia; Shekhar, Sudhanshu & Petersen, Fernanda Cristina (2016). Identification of common surface exposed proteins between S. mitis and S. pneumoniae by cell surface shaving proteomics.
  • Shekhar, Sudhanshu (2016). Chairman.

Se alle arbeider i Cristin

Publisert 5. jan. 2016 10:45 - Sist endret 21. apr. 2020 15:08