Sigurd Schneider

• Henderson, Elisabet; Schneider, Sigurd; Petersen, Fernanda Cristina; Haugen, Håvard Jostein; Wohlfahrt, Johan Caspar & Ekstrand, Karl [Show all 7 contributors for this article] (2013). Chemical debridement of contaminated titanium surfaces: An in vitro study. Acta Odontologica Scandinavica. ISSN 0001-6357. 71(3-4), p. 957–964. doi: 10.3109/00016357.2012.734423. Full text in Research Archive Show summary

  Abstract Objective. To compare the efficacy of different chemical solutions when used for chemical debridement of biofilm contaminated titanium surfaces in an in-vitro experimental study. Materials and methods. Commercially pure titanium discs with a diameter of 6.2 mm and height of 2 mm, mirror-polished with a measured surface amplitude value S(A) = 0.037 μm ± 0.009 were used as test-surfaces. A biofilm was simulated with multi-layers of Staphylococcus epidermidis ATCC359844 covering the entire titanium surface. The chemical agents tested were: 3% H(2)O(2), 0.2% Chlorhexidine, 24% EDTA-gel, 3% H(2)O(2) mixed with 1.6 g/L TiO(2) and sterile saline solution. The decontamination effect was evaluated by optical density analysis using spectrophotometry and with scanning electron microscopy (SEM) images of the remaining biofilm. Results. The suspensions of 3% H(2)O(2) and 1.6 g/L TiO(2) or 3% H(2)O(2) alone were the most effective in removing S. epidermidis biofilms (p < 0.05), whereas 0.2% chlorhexidine or 24% EDTA gel had no significant effects. SEM images of the remaining biofilms supported the quantitative results indicating the higher efficacy of 3% H(2)O(2) and 1.6 g/L TiO(2) or 3% H(2)O(2) alone. It also revealed that EDTA, despite a non-significant effect on reducing the amount of established biofilms, was able to alter the biofilm architecture, as demonstrated by increased interspaced regions. Conclusions. In this in vitro study the decontamination potential of a suspension of 3% H(2)O(2) and 1.6 g/L TiO(2) or 3% H(2)O(2) alone were encouraging. Whether such procedures would have a similar effect in vivo remains to be determined.

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• Schneider, Sigurd; Henderson, Elisabet; Wohlfahrt, Johan Caspar; Taxt-Lamolle, Sebastien Francis Michel; Gustumhaugen, Eva & Petersen, Fernanda Cristina [Show all 9 contributors for this article] (2011). A nano chemical debridement solution shows high efficiency on contaminated titanium surface. European Cells and Materials. 21, p. 19–19. Full text in Research Archive

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