Vitamine D and periodontitis

Objectives

The aim of the study was to assess the radiographic bone level and levels of serum VitD in ethnic Norwegian and Tamil periodontitis patients and their healthy controls.

Outcomes

VitD levels were lower in Norwegian periodontitis patients than in controls, while no statistically significant differences were observed between Tamil periodontitis patients and controls despite the significant difference between RBL between the periodontitis patients and controls in both groups. When calculating the odds ratio for having periodontal disease in both populations together, it appeared that one unit increased serum VitD (i.e. 1 nmol/L) decreased the odds of having radiographic bone loss by 4%.

Results

Raw data

Logistic regression

Supplementary table 1

Supplementary table 2

Background

Studies suggest association between low serum 25-OH-Vitamin D3 (VitD) and chronic destructive periodontal disease. The main sources of VitD is sun exposure and fat fish. Subjects with dark skin will therefore generate less VitD as response to sun exposure. 

Conclusion

According to the logistic regression, after correcting for confounding factors, VitD level showed significant association with the presence of periodontitis, as expressed by radiographic bone loss.

Published Mar. 21, 2019 3:26 PM - Last modified Mar. 22, 2019 12:06 PM