Maria Landin
Professional interests
- miRNAs, ncRNAs and lncRNAs as regulators of the transcriptome
- Transcriptome
- Bioinformatics
- Tooth and craniofacial development
- Biomaterials
- Toxicogenomics/ General toxicology
- Embryology, Genetics, Immunology
- Brominated flamme retardants
Education
PhD-Dr Scientist University of Oslo 2011
Cand. Scientist University of Oslo 2005
Cand. Mag. University of Oslo 2002
Academic Activity
-During her PhD, she investigated and mapped the global gene
expressionin murine toothbuds using molecular biological Methods.
This resulted in the creation of a transcriptome database
(68 microarrays) entailing 16 time points of murine tooth
Development from the embryonic day 11th up to 8 days
post-partum (E11.5- P7).This novel method gave a better picture
of the Genetic events occuring during murine tooth Development.
-Identified new genes that have not been previously described
in tooth Development.
-She was the first to detect enamel genes (Ambn, Amelx and Enam)
and their translated proteins in tooth buds prior to mineralisation.
These were sensational results in 2006 because these genes
and respective translated proteins were expressed
much earlier than previously assumed.
-Established In Situ hibridisation (Ribo-and oligoprobes) at the institute
from january 2000-2011.
-She also developed a new method for isolation/extraction
of RNA from cells grown on scaffolds at the Oral Research
laboratorium from september 2011-2013
-Currently researching on the rolle microRNAs (miRNAs)
play in the regulationof the murine transcriptome using
loss-of-function studies.
-Main supervisor for PhD candidate Natalie Skalleberg
in the Project : MicroRNAs during murine tooth development
-Editorial Board member/peer reviewer of
American Journal of Bioscience and
Bioengineering, SciencePG
-Colaborates with Linda Bergersen/Cecile Morland Group at IOB
-She also colaborates with the Oral Research laboratorium (ORL/IKO) ,
mlapping the transcriptome in biopsies or cells cultivated under various conditions.
-Participant of the faculty funded Project '' Why do biomaterials fail and how can failure be minimized''. Professor Janne Elin Reseland is the Project leder.
Working atm at the Clinical Research Lab started in Mai 2019-2020
Osmundsen and his Group also built two additional databases (2005-2015):
-A microRNA database comprising around 200 miRNA microarrays covering various developmental stages of murine tooth Development.
-A transcriptome datatbase of around 50 microarrays covering different stages of murine sublingual salivary glands development.
http://loop.frontiersin.org/people/48668/overview
http://www.researchgate.net/profile/Maria_Landin
http://uio.academia.edu/MariaLandin
Citations
http://scholar.google.no/citations?user=NznxQ9UAAAAJ&hl=no
Media contributions
http://www.tannlegetidende.no/i/2012/9/Tidende09-449
http://www.odont.uio.no/iob/om/aktuelt/aktuelle-saker/2015/gener_analysert.html
http://www.forskningstorget.net/
http://www.odont.uio.no/om/aktuelt/aktuelle-saker/2015/full-aktivitet-pa-forskningstorget.html
Favorite URL's
http://www.miljostatus.no/tema/kjemikalier/prioritetslisten/bromerte-flammehemmere/