-
Young Vik, Alix ; Torgersen, Gerald R.; Giertsen, Elin & Skudutyte-Rysstad, Rasa
(2021).
Use of a student response system for teaching radiographic caries detection and treatment planning.
-
Giertsen, Elin
(2016).
Skånsomme tannkremer.
[Fagblad].
Norsk Ukeblad nr. 8/16 s. 18-22.
-
Giertsen, Elin & Jacobsen, Svein
(2012).
W.D. Miller: Pioneren som løste kariesgåten.
Den norske tannlegeforenings tidende.
ISSN 0029-2303.
122(6),
s. 446–450..
-
Giertsen, Elin
(2011).
Kolonisering av ikke-orale Gram-negative bakterier i munnen.
Den norske tannlegeforenings tidende.
ISSN 0029-2303.
121(10),
s. 658–659..
-
Guggenheim, B; Meier, A; Hofer, D; Schmidlin, P; Arthur, RA & Giertsen, Elin
(2011).
Adherence and Persistence of Gram- Non-Oral Bacteria in the Mouth.
Journal of Dental Research.
ISSN 0022-0345.
90: Spec Iss A, Abstract 2957 (IADR/AADR/CADR, San Diego, CA, USA, 16.-19.03.2011).
-
Guggenheim, B; Arthur, R; Schmidlin, P; Hofer, D & Giertsen, E
(2010).
Role of Specific Adherence for Colonization Sequence of Oral Microbiota.
Journal of Dental Research.
ISSN 0022-0345.
89: Spec Iss B, Abstract 125 (IADR/AADR 88th General Session, Barcelona, Spania).
-
Quevedo, B; Giertsen, E; Zijnge, V; Lüthi-Schaller, H; Guggenheim, B & Thurnheer, T
[Vis alle 7 forfattere av denne artikkelen]
(2010).
Identification and Enumeration of Lactic Acid Bacteria by FISH.
Journal of Dental Research.
ISSN 0022-0345.
89: Spec Iss B, Abstract 3686(IADR/AADR 88th General Session, Barcelona, Spania).
-
Giertsen, Elin
(2010).
Betydning av spesifikk adhesjon for kolonisering av orale mikroorganismer.
Den norske tannlegeforenings tidende.
ISSN 0029-2303.
120(10),
s. 723–724..
-
Giertsen, Elin
(2010).
Type 2-diabetes og tannhelse.
-
Giertsen, Elin; Olsen, Ingar; Petersen, Fernanda Cristina & Scheie, Anne Aamdal
(2009).
Oral biofilm.
Jubileumshefte for Det odontologiske fakultet.
s. 17–19..
-
Arthur, Rodrigo; Meier, André; Guggenheim, Bernhard & Giertsen, Elin
(2009).
Development of a Local Demineralization Biofilm Model to Study the Cariogenic Potential of Oral Bacteria.
-
Giertsen, Elin
(2009).
Orale biofilmmodeller-nye muligheter for plakkstudier.
-
Giertsen, Elin
(2009).
Type 2-diabetes og tannhelse.
-
Giertsen, Elin
(2008).
Orale biofilmmodeller - nye muligheter for plakkstudier.
-
Giertsen, Elin
(2008).
Type 2-diabetes og tannhelse.
-
Giertsen, Elin; Guggenheim, B & Gmür, R
(2007).
Antiplaque effects of ethyl lauroyl arginine in situ.
-
Giertsen, Elin
(2007).
Orale biofilmmodeller - nye muligheter for plakkstudier.
-
Giertsen, Elin
(2006).
Orale biofilmer - nye muligheter for plakkstudier.
-
Thurnheer, Thomas; Giertsen, Elin & Guggenheim, Bernhard
(2006).
Effect of starch on microbial composition, structure, diffusion properties and demineralization potential of oral biofilms.
-
Giertsen, Elin & Guggenheim, Bernhard
(2005).
Effect of xylitol on survival of mutans streptococci in biofilms.
Journal of Dental Research.
ISSN 0022-0345.
84: Spec Iss A, Abstract 1506(IADR/AADR/CADR, Baltimore, Maryland, USA).
-
Guggenheim, Bernhard; Gmür, Rudolf & Giertsen, Elin
(2005).
Starch: Effect on microbial composition and demineralization potential.
Journal of Dental Research.
ISSN 0022-0345.
84: Spec Iss A, Abstract 1509(IADR/AADR/CADR, Baltimore, Maryland, USA).
-
Giertsen, Elin
(2005).
Does xylitol work in biofilms?
-
Guggenheim, Bernhard & Giertsen, Elin
(2005).
Impact of biofilm research on dentistry.
-
Thurnheer, Thomas; van der Ploeg, Jan R.; Giertsen, Elin & Guggenheim, Bernhard
(2005).
Effects of Streptococcus mutans gtf-deficiency on mixed oral biofilms in vitro.
-
Guggenheim, Bernhard & Giertsen, Elin
(2004).
Comparative Effect of Antimicrobials in Biofilm Versus an Animal Study.
-
Giertsen, Elin
(2003).
In vitro biofilmmodell. In situ kariesmodell.
-
Guggenheim, B; Gmür, R; van der Ploeg, JR; Giertsen, Elin & Thurnheer, T
(2003).
Impact of biofilm models in preventive dentistry.
-
van der Ploeg, JR; Giertsen, Elin; Lüdin, B; Mörgeli, C; Zinkernagel, AS & Gmür, R
(2003).
Quantitative detection of Porphyromonas gingivalis fimbrial genotypes in Europeans.
Journal of Dental Research.
ISSN 0022-0345.
82: Spec Iss B: B-248, Abstract 1894(IADR, Göteborg, Sverige, juni 2003).
-
Guggenheim, B; Giertsen, Elin & Gmür, R
(2003).
Demineralization and remineralization of enamel in the Zürich biofilm model.
Journal of Dental Research.
ISSN 0022-0345.
82: Spec Iss B: B-244, Abstract 1861(IADR, Göteborg, Sverige, juni 2003).
-
Guggenheim, B. & Giertsen, Elin
(2002).
Comparative antimicrobial efficacy of antiplaque agents in a biofilm model.
-
Shapiro, S.; Giertsen, Elin & Guggenheim, B
(2002).
Comparative efficacies of antimicrobial mouthrinses in a modified biofilm model.
-
Lygre, Henning; Moe, Grete; Holmsen, Holm; Skålevik, Rita & Giertsen, Elin
(2002).
Interaksjoner mellom triklosan og membranlipider.
Vis sammendrag
Molekylære vekselvirkninger mellom triklosan/kopolymer som er tilsetningsstoffer i tannpasta, og modellmembraner av eukaryote lipider ble studert med to metoder. Trykk/areal isotermer ble først bestemt ved 37oC ved Langmuir teknikk. Deretter ble faseoverganger for liposomer målt ved hjelp av kalorimetri. Triklosan vekselvirket med mettete fosfolipider. Blandinger med triklosan og kopolymer vekselvirket også klart med fosfolipider.
-
Giertsen, Elin
(2001).
Fluorinnhold i tannkremer.
NORTANN (Personalavis for Den offentlige tannhelsetjenesten i Nordland).
11,
s. 10–11..
-
Giertsen, Elin
(2001).
Forskningsrapport i Fasett 2001; Volum 36: s. 30-33.
I [Mangler etternavn], [Mangler fornavn] (Red.),
Fasett, Tidsskrift for tannlege- og tanpleierstudenter i Bergen.
Universitetet i Bergen.
s. 30–33..
-
Giertsen, Elin
(2001).
Hvordan kan vi få mer tverrfaglig forskning med klinisk relevans? Populærvitenskapelig innlegg. "Omorganisering av Laboratorium for odontologisk forskning".
-
Giertsen, Elin
(2001).
Kost og karies.
-
Giertsen, Elin; Jacobsen, K & Guggenheim, B
(2000).
Effects of Caseinoglycomacropeptide, Micellar Casein-Based Drink, and Renneted Milk on Acid Formation by Dental Plaque.
-
Giertsen, Elin
(1999).
Om erosjoner. Intervju.
[Avis].
Bergensavisen, s. 8.
-
Schuepbach, P; Lutz, F; Guggenheim, B & Giertsen, Elin
(1999).
Efficacy of an alkaline glass composite to prevent secondary caries.
Vis sammendrag
The aim of this study was to compare an alkaline glass composite Ariston pHC (treatment A) which releases fluoride-, hydroxyl- and Ca2+-ions with a fluoride releasing glass ionomer cement Ketac. (trt. B) for its efficacy in preventing secondary caries. This was achieved by comparing the two test materials with the non-fluoride releasing Tetric Ceram (trt C) as control. An in situ model was used to evaluate demineralization of enamel across standardized gaps between enamel and filling material. In addition, the effect of the Ariston Liner applied in the gap between Ariston pHC and enamel was assessed (trt. D). Acrylic appliances, attached to teeth 36 and 46, were worn day and night by 8 students during 7 days. Each appliance had two chambers, in each of which a piece of filling material and a piece of bovine enamel separated by a 100 um gap was mounted. The appliances were immersed eight times daily for 10 min in a sugar solution (3% glucose, 3% sucrose, 70 mM NaCl, 70 mM KCI, 2 mM MgCl2, pH 5.5). The extent of demineralization was measured by confocal microscopy. The specimens were stained during 24 h with a 0.1 mM solution of Rhodamine B and then dipped in H2O during 10 s. The specimens were examined under a confocal Axioplan-LM with an attached argon-crypton laser equipped with a water immersion 25x-objective. The digital images were further processed using image-processing software. The median volumes of demineralization of these treatments were: A 1.2x106; B 7.9x106; C 8.3x106 and D 5.8x106 um3, whereby A was significantly (p<0.01) lower than B and C, and D was significantly (p<0.05) lower than C. Ariston pHC in contrast to Ketac substantially reduced demineralization of adjacent enamel. However, its efficacy was markedly reduced by the application of Ariston Liner.
-
Thurnheer, T; Giertsen, Elin; Guggenheim, B & Gmür, R
(1999).
Validation of an automated immunofluorescence technique for supragingival plaque analyses.
Vis sammendrag
The purpose of this study was to validate automated immunofluorescence (IF) for the enumeration of selected species in dental plaque of great complexity. To this end supragingival plaque samples were studied in parallel by Kontron's image processing system (IBAS) connected to a SIT camera-equipped IF microscope and by conventional IF microscopy. 46 plaque samples from an in situ demineralization model were coated to multi-well microscope slides. Wells were IF stained with well characterized monoclonal antibodies specific for Actinomyces naeslundii, Fusobacterium nucleatum, Prevotella intermedia/P. nigrescens, Streptococcus gordonii/S. oralis/S. sanguis, Streptococcus sobrinus, or Veillonella dispar/V. parvula using a standard three-step procedure. Video images from multiple, automatically visited, areas of wells were collected and processed by IBAS to identify and enumerate fluorescent objects of interest. Automated IF-analysis and counting of fluorescently labeled bacteria by eye were performed by different investigators not knowing each others data. Results showed satisfactory levels of correspondence with correlation coefficients of r=0.90 for the S. gordonii group, r=0.79 for A. naeslundii, r= 0.77 for V. parvula/dispar, r=0.91 for P. intermedia/nigrescens, r=0.66 for F. nucleatum, and r=0.73 for S. sobrinus. Differences between the two methods were due to strong aggregation (e.g., A. naeslundii), irregular cell wall IF (S. sobrinus), or very low target cell density (F. nucleatum). This work demonstrates the applicability of automated IF analysis for such complex test systems as supragingival plaques. As with all other microbiological assay techniques, insufficient plaque disaggregation is a concern. Supported by Unilever Research, Port Sunlight, England.
-
Giertsen, Elin; Schüpbach, P; Lutz, F & Guggenheim, B
(1998).
An in situ model for dental plaque and demineralization studies.
Journal of Dental Research.
ISSN 0022-0345.
77: Spec Iss A: Abstract 1209, s. 257(AADR/CADR, Minneapolis, Minnesota, USA).
-
Giertsen, Elin; Guggenheim, B.; Schüpbach, P. & Gmür, R
(1998).
In situ model for studies of plaque microbiota and enamel demineralization.
Journal of Dental Research.
ISSN 0022-0345.
77: Spec Iss B: Abstract 1206, s. 782(IADR, Nice, Frankrike, 24.06.1998-27.06.1998 ).
Vis sammendrag
The validity of an in situ model to study dental plaque microbiota and enamel demineralization was tested. Acrylic appliances, attached to teeth 36 and 46 and each containing two bovine enamel discs, were worn day and night by 11 students during two 1-week test periods. The appliances were immersed 8 times daily for 10 min in a glucose/sucrose solution and kept in a phosphate buffer during meals and tooth cleaning. Twice daily each appliance was dipped for 1 min into one of the following four solutions (A-D) using a double-blind, cross-over design: A: H2O (control); B: 26.3 mM NaF; C: 20 mM zinc acetate; D: NaF + zinc. Biofilms from each disc were collected by scraping and resuspended in acetate buffer. The microbiota were analyzed using both non-selective and selective culture techniques. Viability was assessed with the live/dead stain. In addition, total cell numbers (TCN) were determined with the Sytox® stain. Total CFU, total streptococci, mutans streptococci, black pigmented bacteria, and % live cells were within the same range for each treatment. Total CFU and TCN correlated well. Eight plaque samples from treatment A were further analyzed quantitatively for 13 taxa by immunofluorescence (IF) with monoclonal antibodies. Great inter-individual variations in plaque composition were observed; the sum of the 13 taxa studied constituted between 10-97% (mean 34%) of TCN. The extent of demineralization was measured within a defined space of all posterior discs using confocal laser-scanning microscopy. The median volumes of complete demineralization per treatment were: A , 26.3x106 µm3; B, 0.0x106 µm3; C, 4.7x106 µm3; and D, 4.4x106 µm3; whereby B was significantly (p<0.05) lower than the other treatments, and D was significantly (p<0.05) lower than A. With 4 subjects, 2.2 mM chlorhexidine and NaF+CHX were also tested. A marked bactericidal effect and no demineralization resulted. We show that this model is valid to study effects of agents interfering with plaque microbiota and caries formation. Supp. by Colgates forskningsfond, Norway and Norsk Dental Depots fond, Bergen.
-
Guggenheim, Bernhard; Schüpbach, P.; Giertsen, Elin & Gmür, R
(1998).
Validation of a new biofilm model.
Vis sammendrag
The study of biofilm structure and function mandates the use of model systems for which a host of environmental variables can be rigorously controlled. We describe a model of supragingival plaque containing Actinomyces naeslundii, Veillonella dispar, Fusobacterium nucleatum, Streptococcus sobrinus, and Streptococcus oralis wherein cells are cultivated anaerobically in a saliva-based medium on hydroxyapatite discs coated with a salivary pellicle, with material and pieces of apparatus common to all microbiology laboratories. After 0.5 hr, 16.5 hrs, 40.5 hrs, and 64.5 hrs, the composition of adherent biofilms was analyzed by culture techniques, live/dead fluorescence staining, and confocal laser scanning microscopy. Repeated independent trials demonstrated the repeatability of biofilm formation after 40.5 hrs and 64.5 hrs. Brief exposures of biofilms to chlorhexidine or Triclosan produced losses in viability similar to those observed in vivo. This biofilm model should prove very useful for pre-clinical testing of prospective anti-plaque agents at clinically relevant concentrations.
-
Giertsen, Elin
(1997).
Bactericidal versus bacteriostatic strategies for dental plaque control.
-
Giertsen, Elin
(1997).
Sukkererstatninger - betydning i kariesprofylaksen? Nyere forskning.
-
Giertsen, Elin
(1997).
A new in situ model for studies of dental plaque and demineralization of enamel.
-
Giertsen, Elin
(1997).
In situ biofilm models for studies of dental plaque.
-
Giertsen, Elin
(1997).
Möglichkeiten der Plaqueprävention.
Dental Forum.
ISSN 0924-9273.
7(1),
s. 28–33..
-
Giertsen, Elin
(1996).
Effekt av xylitol og fluorid på glykolytisk aktivitet i plakk.
Den norske tannlegeforenings tidende.
ISSN 0029-2303.
106(12),
s. 575–575..
-
Giertsen, Elin
(1996).
Tannkrem mot sår i munnen.
[Avis].
Allers, HELSE & medisin, nr. 10, s. 85.
-
Giertsen, Elin
(1996).
Plakkhemmende stoffer – er de effektive?
-
Giertsen, Elin
(1996).
Xylitol - spesiell betydning i kariesprofylaksen?
-
Giertsen, Elin
(1996).
Effects of chlorhexidine, triclosan and zinc ions on dental plaque.
-
Giertsen, Elin
(1996).
Effects of fluoride and xylitol on dental plaque and saliva.
-
Giertsen, Elin
(1996).
Effects of chlorhexidine, triclosan and zinc ions on dental plaque.
-
Giertsen, Elin & Scheie, AAa
(1996).
Effects of fluoride and xylitol on plaque glycolysis .
Journal of Dental Research.
ISSN 0022-0345.
75: Spec Iss: Abstract 646, s. 98(IADR, San Francisco, Calif., USA, 13.03-17.03 1996).
-
Giertsen, Elin
(1996).
Håndhygiene i tannlegepraksis. Anbefalinger fra European Panel for Infection Control in Dentistry.
Den norske tannlegeforenings tidende.
ISSN 0029-2303.
106,
s. 174–177. .
-
Giertsen, Elin
(1995).
Effekter av xylitol og fluorid på plakkdannelse, gingivitt og salivær mikroflora.
Den norske tannlegeforenings tidende.
ISSN 0029-2303.
105(5),
s. 272–272..
-
Giertsen, Elin & Scheie, AAa
(1995).
Effects of fluoride, chlorhexidine and zinc ions on dental plaque.
Journal of Dental Research.
ISSN 0022-0345.
74: Spec Iss: Abstract 518, s. 76(AADR/CADR, San Antonio, Texas, USA, mars 1995).
-
Giertsen, Elin
(1994).
Bakteriedrepende og/eller syrehemmende effekter av klorheksidin munnskylling på tannplakk?
Den norske tannlegeforenings tidende.
ISSN 0029-2303.
104(5),
s. 198–199..
-
Giertsen, Elin
(1994).
Foredrag: Egne erfaringer med veiledere i Oslo og i Rochester. Seminaret "Dr. odont. og veilederfunksjonen i den organiserte forskerutdanningen" for stipendiater og veiledere ved Det odontologiske fakultet, UiO. Lysebu, Oslo, Norge.
-
Giertsen, Elin; Scheie, AAa & Emberland, H
(1994).
Effects of xylitol and fluoride on dental plaque formation, gingivitis and salivary microflora.
Caries Research.
ISSN 0008-6568.
28: Abstract 58, s. 197(ORCA, Cork, Irland, 29.06-02.07 1994 ).
-
Arneberg, Pål; Giertsen, Elin; Emberland, H & Øgaard, B
(1994).
Total fluoride and pH in local plaque environments.
-
Emberland, Hege; Giertsen, Elin & Scheie, AAa
(1994).
Effects of xylitol/fluoride on plaque acidogenicity and salivary flow rate.
-
Giertsen, Elin & Scheie, AAa
(1993).
Effects of fluoride and zinc ions on acid formation by dental plaque.
Caries Research.
ISSN 0008-6568.
27: Abstract 115, s. 239(ORCA, Dresden, Tyskland, juli 1993).
-
Giertsen, Elin & Scheie, AAa
(1993).
Bactericidal versus antiglycolytic effects of chlorhexidine mouthrinse on dental plaque.
-
Kari, S; Levomæki, R; Scheie, AAa & Giertsen, Elin
(1993).
Plaque pH response, acid profile, and bacterial counts at various areas.
-
Young Vik, Alix & Giertsen, Elin
(2015).
Sukkererstatninger og tannhelse: Har xylitol antikariogen effekt?
Universitetet i Oslo.
-
Giertsen, Elin; Olsen, Ingar & Guggenheim, Bernhard
(2010).
Importance of Specific Adherence for Colonization of Microorganisms in the Oral Cavity.
Bibsys.
-
Giertsen, Elin
(2009).
Alternative søtningsmidler - betydning for generell og oral helse.
Bibsys.
-
Giertsen, Elin
(2009).
Tannpleiemidler - hva består de av og hvorfor.
Bibsys.