Trude Marie Haug

Bilde av Trude Marie Haug
English version of this page
Telefon +47 22844414
Rom A1.M068
Brukernavn
Besøksadresse Sognsvannsveien 10 Domus Odontologica 0372 Oslo
Postadresse Postboks 1052 Blindern 0316 Oslo

Faglige interesser

Spyttkjertelcellers fysiologi. Ekstracellulære vesikler fra kreftceller. Elektrofysiologi, nevroendokrinologi, intracellulær signalisering.   

 

Metoder

  • Patch-clamp
  • Ca2+-imaging

 

Undervisning

TP1100, TP1200, OD2100, OD2200, MED2200

 

Bakgrunn

Dr. Scient 1999 UiO, Cand. Scient. 1996 UiO.

 

Tidligere stillinger

Førsteamanuensis ved Atlantis Medisinske Høgskole 2014-2017, Post-doc/Forsker/Gruppeleder ved Universitetet i Oslo 2002-2014, Post-doc ved UCLA, USA 2000-2001.

Emneord: Spyttkjertler, ekstracellulære vesikler, oral kreft, fysiologi, elektrofysiologi, TP1100, OD2100, OD2200

Publikasjoner

  • Haugsten, Helene Rygvold; Kristoffersen, Anne Karin; Haug, Trude Marie; Søland, Tine Merete; Øvstebø, Reidun & Aass, Hans Christian [Vis alle 8 forfattere av denne artikkelen] (2023). Isolation, characterization, and fibroblast uptake of bacterial extracellular vesicles from Porphyromonas gingivalis strains. MicrobiologyOpen. ISSN 2045-8827. 12(5). doi: 10.1002/mbo3.1388.
  • Grønlien, Heidi Kristine; Fontaine, Romain; Hodne, Kjetil; Tysseng, Linn Isabelle; Ager-Wick, Eirill & Weltzien, Finn-Arne [Vis alle 7 forfattere av denne artikkelen] (2021). Long extensions with varicosity-like structures in gonadotrope Lh cells facilitate clustering in medaka pituitary culture. PLOS ONE. ISSN 1932-6203. 16(1). doi: 10.1371/journal.pone.0245462. Fulltekst i vitenarkiv
  • Ciani, Elia; Haug, Trude M; Maugars, Gersende Marie Aimee; Weltzien, Finn-Arne; Falcón, Jack & Fontaine, Romain (2021). Effects of Melatonin on Anterior Pituitary Plasticity: A Comparison Between Mammals and Teleosts. Frontiers in Endocrinology. ISSN 1664-2392. 11, s. 1–20. doi: 10.3389/fendo.2020.605111. Fulltekst i vitenarkiv
  • Berntsen, Hanne Friis; Moldes-Anaya, Angel; Bjørklund, Cesilie Granum; Ragazzi, Lorenzo; Haug, Trude M & Strandabø, Rønnaug [Vis alle 10 forfattere av denne artikkelen] (2020). Perfluoroalkyl acids potentiate glutamate excitotoxicity in rat cerebellar granule neurons. Toxicology. ISSN 0300-483X. 445. doi: 10.1016/j.tox.2020.152610. Fulltekst i vitenarkiv
  • von Krogh, Kristine; Ropstad, Erik; Nourizadeh-Lillabadi, Rasoul; Haug, Trude & Weltzien, Finn-Arne (2019). In Vitro Effects of Bisphenol A and Tetrabromobisphenol A on Cell Viability and Reproduction-Related Gene Expression in Pituitaries from Sexually Maturing Atlantic Cod (Gadus morhua L.). Fishes. ISSN 2410-3888. 4(3). doi: 10.3390/fishes4030048. Fulltekst i vitenarkiv
  • Fontaine, Romain David; Ciani, Elia; Haug, Trude M; Hodne, Kjetil; Ager-Wick, Eirill & Baker, Dianne [Vis alle 7 forfattere av denne artikkelen] (2019). Gonadotrope plasticity at cellular, population and structural levels: A comparison between fishes and mammals. General and Comparative Endocrinology. ISSN 0016-6480. 287, s. 1–20. doi: 10.1016/j.ygcen.2019.113344. Fulltekst i vitenarkiv
  • Tennøe, Simen; Hodne, Kjetil; Haug, Trude; Weltzien, Finn-Arne; Einevoll, Gaute & Halnes, Geir (2019). [Re] Fast-Activating Voltage- and Calcium-Dependent Potassium (BK) Conductance Promotes Bursting in Pituitary Cells: A Dynamic Clamp Study. ReScience. ISSN 2430-3658. 5(1). doi: 10.5281/zenodo.2611252. Fulltekst i vitenarkiv
  • Halnes, Geir; Tennøe, Simen; Haug, Trude; Einevoll, Gaute; Weltzien, Finn-Arne & Hodne, Kjetil (2019). A computational model for gonadotropin releasing cells in the teleost fish medaka. PLoS Computational Biology. ISSN 1553-734X. 15(8), s. 1–28. doi: 10.1371/journal.pcbi.1006662. Fulltekst i vitenarkiv
  • von Krogh, Kristine; Bjørndal, Gunnveig Toft; Nourizadeh-Lillabadi, Rasoul; Ropstad, Erik; Haug, Trude & Weltzien, Finn-Arne (2019). Cortisol differentially affects cell viability and reproduction-related gene expression in Atlantic cod pituitary cultures dependent on stage of sexual maturation. Comparative Biochemistry and Physiology A. ISSN 1095-6433. 236. doi: 10.1016/j.cbpa.2019.06.017. Fulltekst i vitenarkiv
  • Ager-Wick, Eirill; Hodne, Kjetil; Fontaine, Romain; von Krogh, Kristine; Haug, Trude & Weltzien, Finn-Arne (2018). Preparation of a High-quality Primary Cell Culture from Fish Pituitaries . Journal of Visualized Experiments. ISSN 1940-087X. 2018(138). doi: 10.3791/58159. Fulltekst i vitenarkiv
  • Berntsen, Hanne Friis; Bjørklund, Cesilie Granum; Strandabø, Rønnaug; Haug, Trude; Moldes-Anaya, Angel & Fuentes-Lazaro, Judit [Vis alle 10 forfattere av denne artikkelen] (2018). PFOS-induced excitotoxicity is dependent on Ca2+ influx via NMDA receptors in rat cerebellar granule neurons. Toxicology and Applied Pharmacology. ISSN 0041-008X. 357, s. 19–32. doi: 10.1016/j.taap.2018.08.015. Fulltekst i vitenarkiv
  • von Krogh, Kristine; Bjørndal, Gunnveig Toft; Nourizadeh-Lillabadi, Rasoul; Hodne, Kjetil; Ropstad, Erik & Haug, Trude M [Vis alle 7 forfattere av denne artikkelen] (2017). Sex steroids differentially regulate fshb, lhb and gnrhr expression in Atlantic cod (Gadus morhua). Reproduction. ISSN 1470-1626. 154(5), s. 581–594. doi: 10.1530/REP-17-0208.
  • Strandabø, Rønnaug; Grønlien, Heidi Kristine; Ager-Wick, Eirill; Nourizadeh-Lillabadi, Rasoul; Hildahl, Jon Paul & Weltzien, Finn-Arne [Vis alle 7 forfattere av denne artikkelen] (2016). Identified lhb-expressing cells from medaka (Oryzias latipes) show similar Ca2+-response to all endogenous Gnrh forms, and reveal expression of a novel fourth Gnrh receptor. General and Comparative Endocrinology. ISSN 0016-6480. 229, s. 19–31. doi: 10.1016/j.ygcen.2016.02.019.
  • Sandvik, Guro Katrine; Hodne, Kjetil; Haug, Trude M; Okubo, Kataaki & Weltzien, Finn-Arne (2014). RFamide peptides in early vertebrate development. Frontiers in Endocrinology. ISSN 1664-2392. 5:203. doi: 10.3389/fendo.2014.00203. Fulltekst i vitenarkiv
  • Weltzien, Finn-Arne; Hildahl, Jon Paul; Hodne, Kjetil; Okubo, Kataaki & Haug, Trude M (2014). Embryonic development of gonadotrope cells and gonadotropic hormones - Lessons from model fish. Molecular and Cellular Endocrinology. ISSN 0303-7207. 385, s. 18–27. doi: 10.1016/j.mce.2013.10.016.
  • Ager-Wick, Eirill; Henkel, Christian W.; Haug, Trude M & Weltzien, Finn-Arne (2014). Using normalization to resolve RNA-seq biases caused by amplification from minimal input. Physiological Genomics. ISSN 1094-8341. 46(21), s. 808–820. doi: 10.1152/physiolgenomics.00196.2013. Fulltekst i vitenarkiv
  • Weltzien, Finn-Arne; Hildahl, Jon Paul; Hodne, Kjetil; Okubo, Kataaki & Haug, Trude M (2014). Embryonic development of gonadotrope cells and gonadotropic hormones - Lessons from model fish. Molecular and Cellular Endocrinology. ISSN 0303-7207. 385(1-2), s. 18–27. doi: 10.1016/j.mce.2013.10.016.
  • Hildahl, Jon Paul; Taranger, Geir Lasse; Norberg, Birgitta; Haug, Trude M & Weltzien, Finn-Arne (2013). Differential regulation of GnRH ligand and receptor genes in the brain and pituitary of Atlantic cod exposed to different photoperiod. General and Comparative Endocrinology. ISSN 0016-6480. 180, s. 7–14. doi: 10.1016/j.ygcen.2012.09.025.
  • Hodne, Kjetil; Strandabø, Rønnaug; von Krogh, Kristine; Nourizadeh-Lillabadi, Rasoul; Sand, Olav & Weltzien, Finn-Arne [Vis alle 7 forfattere av denne artikkelen] (2013). Electrophysiological differences between fshb- and lhb-expresing gonadotropes in primary culture. Endocrinology. ISSN 0013-7227. 154(9), s. 3319–3330. doi: 10.1210/en.2013-1164.
  • Sand, Sverre; Nissen-Meyer, Jon; Sand, Olav & Haug, Trude M (2013). Plantaricin A, a cationic peptide produced by Lactobacillus plantarum, permeabilizes eukaryotic cell membranes by a mechanism dependent on negative surface charge linked to glycosylated membrane proteins. Biochimica et Biophysica Acta - Biomembranes. ISSN 0005-2736. 1828(2), s. 249–259. doi: 10.1016/j.bbamem.2012.11.001.
  • Strandabø, Rønnaug; Hodne, Kjetil; Ager-Wick, Eirill; Sand, Olav; Weltzien, Finn-Arne & Haug, Trude M (2013). Signal transduction involved in GnRH2-stimulation of identified LH-producing gonadotropes from lhb-GFP transgenic medaka (Oryzias latipes). Molecular and Cellular Endocrinology. ISSN 0303-7207. 372(1-2), s. 128–139. doi: 10.1016/j.mce.2013.03.022.
  • Hildahl, Jon Paul; Sandvik, Guro Katrine; Lifjeld, Rikke; Hodne, Kjetil; Nagahama, Y & Haug, Trude M [Vis alle 8 forfattere av denne artikkelen] (2012). Developmental Tracing of Luteinizing Hormone b-Subunit Gene Expression Using Green Fluorescent Protein Transgenic Medaka (Oryzias latipes) Reveals a Putative Novel Developmental Function. Developmental Dynamics. ISSN 1058-8388. 241(11), s. 1665–1677. doi: 10.1002/dvdy.23860.
  • Hodne, Kjetil; von Krogh, Kristine; Weltzien, Finn-Arne; Sand, Olav & Haug, Trude M (2012). Optimized conditions for primary culture of pituitary cells from the Atlantic cod (Gadus morhua). The importance of osmolality, pCO(2), and pH. General and Comparative Endocrinology. ISSN 0016-6480. 178(2), s. 206–215. doi: 10.1016/j.ygcen.2012.06.005.
  • Hildahl, Jon; Sandvik, Guro Katrine; Edvardsen, Rolf; Norberg, Birgitta; Haug, Trude M & Weltzien, Finn-Arne (2011). Four gonadotropin releasing hormone receptor genes in Atlantic cod are differentially expressed in the brain and pituitary during puberty. General and Comparative Endocrinology. ISSN 0016-6480. 173(2), s. 333–345. doi: 10.1016/j.ygcen.2011.06.002.
  • Hildahl, Jon; Sandvik, Guro Katrine; Edvardsen, Rolf; Fagernes, Cathrine Elisabeth; Norberg, Birgitta & Haug, Trude M [Vis alle 7 forfattere av denne artikkelen] (2011). Identification and gene expression analysis of three GnRH genes in female Atlantic cod during puberty provides insight into GnRH variant gene loss in fish. General and Comparative Endocrinology. ISSN 0016-6480. 172(3), s. 458–467. doi: 10.1016/j.ygcen.2011.04.010.
  • Haug, Trude Marie; Sand, Sverre; Sand, Olav; Phung, Danh; Granum, Per Einar & Hardy, Simon P. (2010). Formation of Very Large Conductance Channels by Bacillus cereus Nhe in Vero and GH4 Cells Identifies NheA + B as the Inherent Pore-Forming Structure. Journal of Membrane Biology. ISSN 0022-2631. 237, s. 1–11.
  • Hodne, Kjetil; Haug, Trude M & Weltzien, Finn-Arne (2010). Single-cell qPCR on dispersed primary pituitary cells -an optimized protocol. BMC Molecular Biology. ISSN 1471-2199. 11. doi: 10.1186/1471-2199-11-82.
  • Andersland, Kristin; Jølle, Guro Five; Sand, Olav & Haug, Trude M (2010). Peptide Pheromone Plantaricin A Produced by Lactobacillus plantarum Permeabilizes Liver and Kidney Cells. Journal of Membrane Biology. ISSN 0022-2631. 235(2), s. 121–129. doi: 10.1007/s00232-010-9263-4.
  • Haug, Trude M; Sand, Sverre; Sand, Olav; Phung, Danh; Granum, Per Einar & Hardy, Simon P. (2010). Formation of Very Large Conductance Channels by Bacillus cereus Nhe in Vero and GH(4) Cells Identifies NheA plus B as the Inherent Pore-Forming Structure. Journal of Membrane Biology. ISSN 0022-2631. 237(1), s. 1–11. doi: 10.1007/s00232-010-9298-6.
  • Haug, Trude M; Hodne, Kjetil; Weltzien, Finn-Arne & Sand, Olav (2007). Electrophysiological properties of pituitary cells in primary culture from Atlantic cod (Gadus morhua). Neuroendocrinology. ISSN 0028-3835. 86, s. 38–47. doi: 10.1159/000103867.
  • Sand, Sverre; Haug, Trude M; Nissen-Meyer, Jon & Sand, Olav (2007). The bacterial peptide pheromone plantaricin a permeabilizes cancerous, but not normal, rat pituitary cells and differentiates between the outer and inner membrane leaflet. Journal of Membrane Biology. ISSN 0022-2631. 216(2-3), s. 61–71. doi: 10.1007/s00232-007-9030-3.
  • Hafting, Torkel; Haug, Trude M; Ellefsen, Stian & Sand, Olav (2006). Hypotonic stress activates BK channels in clonal kidney cells via purinergic receptors, presumably of the P2Y1 subtype. Acta Physiologica. ISSN 1748-1708. 188(1), s. 21–32. doi: 10.1111/j.1748-1716.2006.01601.
  • Mørk, Halvor Kjeang; Haug, Trude M & Sand, Olav (2005). Contribution of different Ca-activated K channels to the first phase of the response to TRH in clonal rat anterior pituitary cells. Acta Physiologica Scandinavica. ISSN 0001-6772. 184(2), s. 141–150. doi: 10.1111/j.1365-201X.2005.01441.
  • Haug, Trude M; Sigg, D; Ciani, S; Toro, L; Stefani, E & Olcese, R (2004). Regulation of K+ flow by a ring of negative charges in the outer pore of the BKCa channels. Part I: Aspartate 292 modulates K+ conductance by external surface charge effect. The Journal of General Physiology. ISSN 0022-1295. 124, s. 173–184.
  • Haug, Trude M (2004). Regulation of K+ flow by a ring of negative charges in the outer pore of the BKCa channels. Part II: Ionic and gating currents. The Journal of General Physiology. ISSN 0022-1295. 124, s. 185–197.
  • Haug, Trude M; Hafting, Torkel & Sand, Olav (2004). Inhibition of BK channels contributes to the second phase of the response to TRH in clonal rat anterior pituitary cells. Acta Physiologica Scandinavica. ISSN 0001-6772. 180, s. 347–357.
  • Haug, Trude M & Storm, Johan Fredrik (2000). Protein kinase A mediates the modulation of the slow Ca2+-dependent K+ current, IsAHP, by the neuropeptides CRF, VIP and CGRP in hippocampal pyramidal neurons. Journal of Neurophysiology. ISSN 0022-3077. 83, s. 2071–2079.
  • Pedarzani, P.; Haug, Trude M; Storm, Johan Fredrik & Stühmer, W. (1998). Modulation of the slow Ca2+-activated K+ current sIAHP by a phosphatase/kinase balance under basal conditions in rat CA1 pyramidal neurons. Journal of Neurophysiology. ISSN 0022-3077. 79(6), s. 3252–3256.
  • Haug, Trude M (1998). Molecular determinants of KATP channel inhibition by ATP. EMBO Journal. ISSN 0261-4189. 17, s. 3290–3296.
  • Gribble, Fiona M; Tucker, SJ; Haug, Trude M & Ashcroft, Fran M (1998). MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 95, s. 7185–7190.
  • Haug, Trude M & Sand, Olav (1997). BK channels in intact clonal rat pituitary cells are activated by physiological elevations of the cytosolic Ca2+ concentration at the normal resting potential. Acta Physiologica Scandinavica. ISSN 0001-6772. 161, s. 227–237.

Se alle arbeider i Cristin

  • Halnes, Geir; Tennøe, Simen; Einevoll, Gaute; Haug, Trude; Weltzien, Finn-Arne & Hodne, Kjetil (2019). A computational model of the spontaneous activity of gonadotrophin-releasing cells in the teleost fish models.
  • Mobråten, Kaia; Haug, Trude M; Kleiveland, Charlotte Ramstad & Lea, Tor Erling (2013). Omega-3 and omega-6 PUFAs both activated GPR120 in Caco2 cells.
  • Sand, Sverre L.; Nissen-Meyer, Jon; Sand, Olav & Haug, Trude M (2011). The cationic peptide plantaricin A produced by Lactobacillus plantarum permeabilizes eukaryotic cell membranes by a mechanism dependent on negative surface charge linked to glycosylated membrane proteins. Acta Physiologica. ISSN 1748-1708. 202.
  • Haug, Trude M; Sand, Sverre L.; Phung, Danh; Hardy, Simpn P. & Sand, Olav (2009). The Bacillus cereus Nhe enterotoxin forms gigantic channels in cell membranes. Acta Physiologica. ISSN 1748-1708. 196.
  • Andersland, Kristin; Johansen, Guro Five; Haug, Trude M & Sand, Olav (2008). THE ANTIMICROBIAL PEPTIDE PLANTARICIN A PERMEABILIZES LIVER AND KIDNEY CELLS. Acta Physiologica. ISSN 1748-1708. 193.
  • Haug, Trude M; Hodne, Kjetil; Weltzien, Finn-Arne & Sand, Olav (2007). Signaling properties of teleost gonadotropes with a first study from atlantic cod. Acta Physiologica. ISSN 1748-1708. 190.
  • Sand, Sverre L.; Haug, Trude M; Nissen-Meyer, Jon & Sand, Olav (2006). Clonal rat anterior pituitary cells (GH4 cells) are permeabilized by plantaricin A, a peptide pheromone produced by Lactobacillus plantarum. SFN Abstract Viewer/Itinerary Planner.
  • Sand, Sverre Larsstuvold; Haug, Trude M; Fimland, Gunnar; Nissen-Meyer, Jon & Sand, Olav (2006). Membrane-permeabilizing effects of the bacterial peptide Plantaricin A on rat anterior pituitary cells. Acta Physiologica. ISSN 1748-1708. 187.
  • Haug, Trude M; Hodne, Kjetil; Weltzien, Finn-Arne & Sand, Olav (2006). Electrophysiological properties of pituitary cells in primary cultures from atlantic cod (Gadus morhua). Acta Physiologica. ISSN 1748-1708. 187.
  • Kristiansen, Per Eugen; Sand, Sverre; Haug, Trude M; Sand, Olav; Fimland, Gunnar & Zhao, Hongxia [Vis alle 10 forfattere av denne artikkelen] (2006). Structure and Mode of Action of the Membrane-Permeabilizing Antimicrobial Peptide Pheromone Plantaricin A.
  • Sand, Olav; Haug, Trude M & Mørk, Halvor (2005). Electrophysiological properties of anterior pituitary cells. Acta Physiologica Scandinavica. ISSN 0001-6772. 183.
  • Mørk, Halvor; Haug, Trude M & Sand, Olav (2004). Contribution of different Ca2+-activated K+-channels to the first phase of the TRH response in clonal anterior pituitary cells (GH4 cells). Acta Physiologica Scandinavica. ISSN 0001-6772. 181.
  • Haug, Trude M; Hafting, Torkel & Sand, Olav (2004). Contribution of BK channels to the resting conductance and the second phase of the response to TRH in anterior pituitary cells (GH4C1cells). Acta Physiologica Scandinavica. ISSN 0001-6772. 181.
  • Haug, Trude M; Hafting-Fyhn, Torkel & Sand, Olav (2003). Contribution of BK channels to the second phase of the response to TRH in anterior pituitary cells (GH4 cells). SFN Abstract Viewer/Itinerary Planner.
  • Haug, Trude M; Ciani, Sergio; Toro, Ligia; Stefani, Enrico & Olcese, Riccardo (2003). Neutralization of the aspartate in the GYGD pore sequence affects gating properties in BKCa channels.
  • Haug, Trude M; Olcese, Riccardo; Ciani, Sergio; Toro, Ligia & Stefani, Enrico (2002). Regulation of inward potassium flow by a negative residue in the outer vestibule of the MaxiK channel pore.
  • Stefani, Enrico; Haug, Trude M; Ciani, Sergio; Toro, Ligia & Olcese, Riccardo (2002). Conduction of K ions through BKCa channels is enhanced by a negatively charged residue near the pore (D292).
  • Olcese, Riccardo; Zhu, Ning; Haug, Trude M; Toro, Ligia & Stefani, Enrico (2002). Conformational changes in BK(Ca) channel during channel opening and closing revealed by optical methods.
  • Haug, Trude M; Olcese, Riccardo; Zhu, Ning; Toro, Ligia & Stefani, Enrico (2001). Reduced Ca2+-sensitivity in the D292N mutant of hSlo potassium channel pore.
  • Olcese, Riccardo; Zhu, Ning; Haug, Trude M; Toro, Ligia & Stefani, Enrico (2001). Voltage dependent conformational changes in MaxiK channels assessed by fluorescent labeling.
  • Storm, Johan Fredrik; Pedarzani, P. & Haug, Trude M (2000). Modulation of K+ channels in hippocampal neurons: transmitters acting via cyclic AMP enhance the excitability through kinase-dependent and -independent modulation of AHP- and h-channels.
  • Haug, Trude M & Storm, Johan Fredrik (1998). Peptidergic modulation via protein kinase A of the slow Ca2+-dependent K+ current IAHP in hippocampal pyramidal cells.
  • Haug, Trude M & Sand, Olav (1997). BK-channels in cell-attached patches of clonal pituitary cells (GH4 cells). Abstracts - Society for Neuroscience. ISSN 0190-5295. 23(2).
  • Haug, Trude M & Sand, Olav (1996). Activation of BK-channels in intact clonal pituitary cells. Acta Physiologica Scandinavica. ISSN 0001-6772. 157.
  • Haug, Trude M & Storm, Johan Frederik (1999). Ca2+ -activated and ATP-sensitive potassium channels in endocrine cells and neurons. Unipub forlag.

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Publisert 5. apr. 2017 10:44 - Sist endret 14. sep. 2023 14:05