Siste publikasjoner

• Kruger, Tormod Bjartveit; Herlofson, Bente Brokstad; Lian, Aina-Mari; Syversen, Unni & Reseland, Janne Elin (2021). Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts. Bone Reports.  ISSN 2352-1872.  14:100750, s 1- 7 . doi: 10.1016/j.bonr.2021.100750
• Klemm, Anne & Tiainen, Hanna (2021). Highly porous Sr-doped TiO2 ceramics maintain compressive strength after grain boundary corrosion. Journal of the European Ceramic Society.  ISSN 0955-2219. . doi: 10.1016/j.jeurceramsoc.2021.04.059
• Uhlen, Marte-Mari Nordsetmoen; Ansteinsson, Vibeke Elise; Stangvaltaite-Mouhat, Lina; Korzeniewska, Lubomiła; Skudutyte-Rysstad, Rasa; Shabestari, Maziar; Mdala, Ibrahimu & Hovden, Ewa Alicja Szyszko (2021). Psychological impact of the COVID-19 pandemic on dental health personnel in Norway. BMC Health Services Research.  ISSN 1472-6963.  21(1) . doi: https://doi.org/10.1186/s12913-021-06443-y
• Fostad, Barbro Grunnan; Rongen, Gunnar; Grytten, Jostein Ivar; Koldsland, Odd Carsten & Vandevska-Radunovic, Vaska (2021). Periodontal Status in Long Term Orthodontic Retention Patients up to 10 Years after Treatment - a Cross-Sectional Study. Acta Odontologica Scandinavica.  ISSN 0001-6357.
• Papageorgiou, Spyridon; Cassina, Chiara; Vandevska-Radunovic, Vaska & Eliades, Theodore (2021). Incisor and profile alterations in extraction cases treated with standard Edgewise and pre-adjusted appliances: A controlled before-and-after study. Journal of the World Federation of Orthodontists.  ISSN 2212-4438.  14 . doi: 10.1016/j.ejwf.2021.04.001
• D. Tien, Nguyen; Lyngstadaas, Ståle Petter; Mano, Joao F.; Blaker, Jonny j & Haugen, Håvard Jostein (2021). Recent Developments in Chitosan-Based Micro/Nanofibers for Sustainable Food Packaging, Smart Textiles, Cosmeceuticals, and Biomedical Applications. Molecules.  ISSN 1420-3049.  26(2683), s 1- 24 . doi: 10.3390/molecules26092683 Vis sammendrag

  Chitosan has many useful intrinsic properties (e.g., non-toxicity, antibacterial properties, and biodegradability) and can be processed into high-surface-area nanofiber constructs for a broad range of sustainable research and commercial applications. These nanofibers can be further functionalized with bioactive agents. In the food industry, for example, edible films can be formed from chitosan-based composite fibers filled with nanoparticles, exhibiting excellent antioxidant and antimicrobial properties for a variety of products. Processing ‘pure’ chitosan into nanofibers can be challenging due to its cationic nature and high crystallinity; therefore, chitosan is often modified or blended with other materials to improve its processability and tailor its performance to specific needs. Chitosan can be blended with a variety of natural and synthetic polymers and processed into fibers while maintaining many of its intrinsic properties that are important for textile, cosmeceutical, and biomedical applications. The abundance of amine groups in the chemical structure of chitosan allows for facile modification (e.g., into soluble derivatives) and the binding of negatively charged domains. In particular, high-surface-area chitosan nanofibers are effective in binding negatively charged biomolecules. Recent developments of chitosan-based nanofibers with biological activities for various applications in biomedical, food packaging, and textiles are discussed herein.

• Salata, Camila; de Almeida, Carlos Eduardo; Ferreira-Machado, Samara C.; Barroso, Regina C.; Nogueira, Liebert Parreiras; Mantuano, Andrea; Pickler, Arissa; Mota, Carla Lemos & de Andrade, Cherley B. V. (2021). Preliminary Pre-Clinical studies on the side effects of breast cancer treatment. International Journal of Radiation Biology.  ISSN 0955-3002. . doi: 10.1080/09553002.2021.1919782 Fulltekst i vitenarkiv.
• Reddy, Shiva; Krogvold, Lars; Martin, Charlton; Sun, Kevin Xueying; Martin, Owen; Al-Ani, Aamenah & Dahl-Jørgensen, Knut (2021). Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated. Cell and Tissue Research.  ISSN 0302-766X. . doi: 10.1007/s00441-020-03340-4
• Diep, My Tien; Jensen, Janicke Liaaen; Skudutyte-Rysstad, Rasa; Young, Alix; Sødal, Anne Thea Tveit; Petrovski, Beata & Hove, Lene Hystad (2021). Xerostomia and hyposalivation among a 65-yr-old population living in Oslo, Norway. European Journal of Oral Sciences.  ISSN 0909-8836.  129(1), s 1- 11 . doi: 10.1111/eos.12757
• Hildebrand, Torben; Nogueira, Liebert Parreiras; Sunde, Pia Titterud; Ørstavik, Dag; Glasmacher, Birgit & Haugen, Håvard Jostein (2021). Contrast-enhanced nano-CT reveals dental soft tissues and cellular layers. International Endodontic Journal.  ISSN 0143-2885. . doi: 10.1111/iej.13527 Fulltekst i vitenarkiv. Vis sammendrag

  Aim: Nano-CT technologies offer 3D imaging methods that allow high-resolution examination of bones and teeth, but soft tissue components have weak X-ray attenuation and are not easily visualised in CT images. We introduce a methodology designed to simultaneously visualise dental ultrastructure, including cellular and soft tissue components, by utilising phosphotungstic acid (PTA) as a contrast-enhancement agent. Methodology: Sound third molars were collected from healthy human adults and fixed in 4% buffered paraformaldehyde. To evaluate the impact of PTA in concentrations of 0.3%, 0.7% and 1% on dental soft and hard tissues for CT imaging, cementum and dentine-pulp sections were cut, dehydrated and stained with immersion periods of 12 hours, 24 hours, 2 days or 5 days. The samples were scanned with high-resolution nano-CT, where we examined both the cementum and pulpal regions with pixel sizes down to 0.5 µm for dental-pulp sections. Results: Dental cementum and periodontium as well as odontoblasts and predentine were made visible through PTA-staining in high-resolution three-dimensional nano-CT scans. Different segments of the tooth required different staining protocols. The thickness of the cementum could be computed over the height of the tooth once it was made visible by the PTA-enhanced contrast, and the attached soft tissue components of the interior of the tooth could be shown on the dentine-pulp interface in greater detail. Three-dimensional illustrations allowed a histology-like visualisation of the sections in all orientations with a single scan and easy sample preparation. The segmentation of the sigmoidal dentinal tubules and the surrounding dentine allowed a three-dimensional investigation and quantative of the dentine composition, such as the tubular lumen or the ratio of the tubular lumen area to the dentinal surface. Conclusion: The staining protocol made it possible to visualise hard tissues along with cellular layers and soft tissues using a laboratory-based nano-CT technique. The protocol depended on both tissue type and size. This methodology offers enhanced possibilities for the concomitant visualisation of soft and hard dental tissues.

• Zhu, Hao; Haugen, Håvard Jostein; Perale, Giuseppe; Reseland, Janne Elin; Nogueira, Liebert Parreiras; Cantalapiedra, Antonio gonzalez; Muñoz, Fernando maria guzon; Permuy Mendaña, Maria; Betge, Felice; Lyngstadaas, Ståle Petter & Xiao, Jun (2021). Tailoring Resorption Rates and Osteogenic Response in Xeno-Hybrid Bone Grafts: The Effect of Added Gelatins. Engineering.  ISSN 2095-8099. . doi: 10.1016/j.eng.2021.01.010 Fulltekst i vitenarkiv. Vis sammendrag

  Bone defects resulting from trauma, surgery, congenital malformations, and other factors are among the most common health problems nowadays. Although current strategies such as autografts and allografts are recognized as the most successful treatments for stimulating bone regeneration, limitations such as graft source and complications still exist. SmartBone® is a xeno-hybrid bone graft (made from bovine bone matrix, poly(L-lactic-co-ε-caprolactone), and gelatin) with a positive clinical record for bone regeneration. In this study, the formulation for designing xeno-hybrid bone grafts using gelatins from different sources (bovine- and porcine-derived gelatin, with bone grafts named SBN and SPK, respectively) was investigated, and the biological responses were evaluated in vitro and in vivo. The results demonstrate that gelatins from both bovine and porcine sources can be loaded onto SmartBone® successfully and safely, withstanding the aggressive manufacturing processes. Different bone cell responses were observed in vitro. SBN was found to enhance osteocalcin secretion while SPK was found to upregulate osteopontin from human osteoblasts. In vivo, both bone grafts promoted osteogenesis, but SPK degraded earlier than SBN. Our findings suggest that SBN and SPK provide different yet comparable solutions for optimizing the bone resorption and regeneration balance. These xeno-hybrid bone grafts possess ideal potential for bone defect repairing.

• Esterhazy, Rachelle; de Lange, Thomas & Møystad, Anne (2021). How do signature pedagogies get their signatures? The role of assessment and professional artefacts in preparing students for their professions. Assessment in education: Principles, Policy & Practice.  ISSN 0969-594X. . doi: 10.1080/0969594X.2021.1902273
• Miloš, Danira; Pavlic, Andrej; Vandevska-Radunovic, Vaska; Zigante, Martina; Matthewson, Alana & Špalj, Stjepan (2021). Craniofacial Growth in Adolescence and its Influence on the Mandibular Incisor Crowding. Acta Stomatologica Croatica.  ISSN 0001-7019.  55(1), s 38- 45 . doi: 10.15644/asc55/1/5
• Kise, Yoshitaka; Møystad, Anne; Bjørnland, Tore; Shimizu, Mayumi; Ariji, Yoshiko; Kuwada, Chiaki; Nishiyama, Masako; Funakoshi, Takuma; Yoshiura, Kazunori & Ariji, Eiichiro (2021). Effects of 1 year training on the performance of ultrasonographic image interpretation: A preliminary evaluation using images of Sjogren syndrome patients.. Imaging Science in Dentistry.  ISSN 2233-7822. . doi: 10.5624/isd.20200294
• Vilaça, Adriana; Domingues, Rui M. A,; Tiainen, Hanna; Mendes, Bárbara B.; Barrantes Bautista, Alejandro; Reis, Rui L.; Gomes, Manuela E. & Gomez-Florit, Manuel (2021). Multifunctional surfaces for improving soft tissue integration. Advanced Healthcare Materials.  ISSN 2192-2640. . doi: 10.1002/adhm.202001985 Fulltekst i vitenarkiv.
• Skudutyte-Rysstad, Rasa; Sunde, Pia Titterud; Sen, Abhijit & Jordal, Kristin (2021). Effects of an individualised training course in endodontics on the knowledge and insights of dentists in Public Dental Service in Norway. Acta Odontologica Scandinavica.  ISSN 0001-6357. . doi: 10.1080/00016357.2021.1876915
• Enriquez, J. J. S.; Sena, Gabriela; Braz, Delson; Barroso, Regina C.; Colaço, Marcos; Fidalgo, Gabriel; Nogueira, Liebert Parreiras; Azambuja, Patricia & Gonzalez, Marcelo S. (2021). The Methodology to produce Rhodnius prolixus head structures made by 3D printing using Synchrotron Radiation Microtomography. Journal of Instrumentation (JINST).  ISSN 1748-0221. . doi: 10.1088/1748-0221/16/02/P02014
• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Fjeld, Katrine Gahre; Hove, Lene Hystad; Malterud, Karl Egil; Saghaug, Elisabeth; Slaaen, Joran; Sundal, Tone; Tollisen, Anita & Lerdal, Anners (2021). A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: A randomized controlled trial. Supportive Care in Cancer.  ISSN 0941-4355. . doi: 10.1007/s00520-021-06021-2 Fulltekst i vitenarkiv. Vis sammendrag

  Background: Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. Aim: This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. Design: A block-randomized controlled trial. Data were collected before and after a 4-day intervention with either SO (n=44) or NS (n=44). Numerical rating scales (NRS, 0-10) and 12 items from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Oral Health 17 (EORTC QLQ-OH17) measured patient-reported oral symptoms. An oral examination was performed before and after the intervention. Setting/participants: This study included adult patients with late-stage cancer in an inpatient hospice unit. Results: Of the 88 patients included (mean age=63.9 years, SD=10.6), 73 (83%) completed the study. At baseline, 78% reported dry mouth on the EORTC QLQ-OH17, and 80% rated dry mouth ≥4 on the NRS. Total oral health scores based on the 12 EORTC QLQ-OH17 items improved similarly in both groups (p

• Gerkin, Richard C; Ohla, Kathrin; Veldhuizen, Marie G; Joseph, Paule V; Kelly, Christine E; Bakke, Alyssa J; Singh, Preet Bano; Ahuja, Gaurav; Hummel, Thomas; Reed, Danielle R; Niv, Masha Y; Munger, Steven D & Parma, Valentina (2021). Recent smell loss is the best predictor of COVID-19 among individuals with recent respiratory symptoms.. Chemical Senses.  ISSN 0379-864X. . doi: https://doi.org/10.1093/chemse/bjaa081
• Yang, Yang; Pullisaar, Helen; Landin, Maria Augusta Dos S Silva; Heyward, Catherine Anne; Schröder, Maria; Geng, Tianxiang; Grano, Maria & Reseland, Janne Elin (2021). FNDC5/irisin is expressed and regulated differently in human periodontal ligament cells, dental pulp stem cells and osteoblasts. Archives of Oral Biology.  ISSN 0003-9969. . doi: https://doi.org/10.1016/j.archoralbio.2021.105061 Fulltekst i vitenarkiv.
• Magaz, Andrew; Li, X; Gough, Julie e. & Blaker, Jonathan James (2021). Graphene oxide and electroactive reduced graphene oxide/silk composite fibrous scaffolds for engineering excitable nerve tissue. Materials Science and Engineering C: Materials for Biological Applications.  ISSN 0928-4931.  119 . doi: 1016/j.msec.2020.111632
• Papageorgiou, Spyridon; Tilen, Raphael; Vandevska-Radunovic, Vaska & Eliades, Theodore (2021). Occlusal outcome after orthodontic treatment with preadjusted straight-wire and standard edgewise appliances A retrospective cohort study. Journal of Orofacial Orthopedics.  ISSN 1434-5293. . doi: https://doi.org/10.1007/s00056-020-00273-z Fulltekst i vitenarkiv.
• Thieu, Minh Khai Le; Haugen, Håvard Jostein; Esporrin, Javier Sanz; Sanz, Mariano; Lyngstadaas, Ståle Petter & Verket, Anders (2021). Guided bone regeneration of chronic non-contained bone defects using a volume stable porous block TiO2 scaffold: An experimental in vivo study. Clinical Oral Implants Research.  ISSN 0905-7161. . doi: 10.1111/clr.13708 Vis sammendrag

  Objectives To evaluate new lateral bone formation and lateral volume augmentation by guided bone regeneration (GBR) in chronic non‐contained bone defects with the use of a non‐resorbable TiO2‐block. Materials and methods Three buccal bone defects were created in each hemimandible of eight beagle dogs and allowed to heal for eight weeks before treatment by GBR. Each hemimandible was randomly allocated to 4 or 12‐week healing time after GBR and three intervention groups were assigned by block randomization: TiO2 block: TiO2‐scaffold and a collagen membrane, DBBM particles: Deproteinized bovine bone mineral (DBBM) and a collagen membrane, Empty control: Collagen membrane only. Microcomputed tomography (microCT) was used to measure the lateral bone formation and width augmentation. Histological outcomes included descriptive analysis and histomorphometric measurements. Results MicroCT analysis demonstrated increasing new bone formation from four to twelve weeks of healing. The greatest width of mineralized bone was seen in the empty controls, and the largest lateral volume augmentation was observed in the TiO2 block sites. The DBBM particles demonstrated more mineralized bone in the grafted area than the TiO2 blocks, but small amounts and less than the empty control sites. Conclusion The TiO2 blocks rendered the largest lateral volume augmentation but also less new bone formation compared to the DBBM particles. The most new lateral bone formation outward from the bone defect margins was observed in the empty controls, indicating that the presence of either graft material leads to slow appositional bone growth.

• Di Raimondo, Ricardo; Sanz, Javier; Sanz Martin1, Ignacio; Vignoletti, Fabio; Nuñez, Javi; Muñoz, Fernando; Haugen, Håvard Jostein & Sanz, Mariano (2021). Hard tissue volumetric and soft tissue contour linear changes at implants with different surface characteristics after experimentally induced peri-implantitis: an experimental in vivo investigation. Clinical Oral Investigations.  ISSN 1432-6981. . doi: 10.1007/s00784-020-03720-8 Vis sammendrag

  Objective To evaluate the hard tissue volumetric and soft tissue contour linear changes in implants with two different implant surface characteristics after a ligature-induced peri-implantitis. Material andmethods In eight beagle dogs, implants with the same size and diameter but distinct surface characteristics were placed in the healed mandibular sites. Test implants had an external monolayer of multi-phosphonate molecules (B+), while control implants were identical but without the phosphonate-rich surface. Once the implants were osseointegrated, oral hygiene was interrupted and peri-implantitis was induced by placing subgingival ligatures. After 16 weeks, the ligatures were removed and peri-implantitis progressed spontaneously. Bone to implant contact (BIC) and bone loss (BL) were assessed three-dimensionally with Micro-Ct (μCT). Dental casts were optically scanned and the obtained digitalized standard tessellation language (STL) images were used to assess the soft tissue vertical and horizontal contour linear changes. Results Reduction of the three-dimensional BIC percentage during the induction and progression phases of the experimental peri-implantitis was similar for both the experimental and control implants, without statistically significant differences between them. Soft tissue analysis revealed for both implant groups an increase in horizontal dimension after the induction of peri-implantitis, followed by a decrease after the spontaneous progression period. In the vertical dimension, a soft tissue dehiscence was observed in both groups, being more pronounced at the buccal aspect. Conclusions The added phosphonate-rich surface did not provide a more resistant environment against experimental periimplantitis, when assessed by the changes in bone volume and soft tissue contours. Clinical relevance Ligature-induced peri-implantitis is a validated model to study the tissue changes occurring during peri-implantitis. It was hypothesized that a stronger osseointegration mediated by the chemical bond of a phosphonaterich implant surface would develop an environment more resistant to the inflammatory changes occurring after experimental peri-implantitis. These results, however, indicate that the hard and soft tissue destructive changes occurring at both the induction and progression phases of experimental peri-implantitis were not influenced by the quality of osseointegration.

• Sena, Gabriela; Barroso, Regina C.; Braz, Delson; Nogueira, Liebert Parreiras; Colaço, Marcos; Kourousias, George; Tromba, Giuliana; Azambuja, Patricia; Gonzales, Marcelo; Pickler, Arissa; Fidalgo, Gabriel; Paiva, Katrine & Barcellos, Renan (2021). Evaluation of the effects of Azadirachtin on internal structures of Rhodnius prolixus head using low-energy X-ray microfluorescence. Spectrochimica Acta Part B - Atomic Spectroscopy.  ISSN 0584-8547. . doi: 10.1016/j.sab.2020.106064
• Colaço, Marcos; Camara, Alexandre Resende; Nogueira, Liebert Parreiras; Carvalho, Isabel C. S.; Margulis, Walter & Barroso, Regina C. (2021). Characterization of microstructures of specialty optical fibers for electric field sensing by propagation-based X-ray phase-contract tomography. Measurement Science and Technology.  ISSN 0957-0233. . doi: 10.1088/1361-6501/abd365 Fulltekst i vitenarkiv.
• Vyas, Cian; Zhang, Jun; Øvrebø, Øystein; Huang, Boyang; Roberts, Iwan; Setty, Mohan; Allardyce, Benjamin J; Haugen, Håvard Jostein; Rajkhowa, Rangam & Bàrtolo, Paulo Jorge da Silva (2021). 3D printing of silk microparticle reinforced polycaprolactone scaffolds for tissue engineering applications. Materials Science and Engineering C: Materials for Biological Applications.  ISSN 0928-4931.  118, s 111433 . doi: 10.1016/j.msec.2020.111433 Fulltekst i vitenarkiv. Vis sammendrag

  Polycaprolactone (PCL) scaffolds have been widely investigated for tissue engineering applications, however, they exhibit poor cell adhesion and mechanical properties. Subsequently, PCL composites have been produced to improve the material properties. This study utilises a natural material, Bombyx mori silk microparticles (SMP) prepared by milling silk fibre, to produce a composite to enhance the scaffolds properties. Silk is biocompatible and biodegradable with excellent mechanical properties. However, there are no studies using SMPs as a reinforcing agent in a 3D printed thermoplastic polymer scaffold. PCL/SMP (10, 20, 30 wt. %) composites were prepared by melt blending. Rheological analysis showed that SMP loading increased the shear thinning and storage modulus of the material. Scaffolds were fabricated using a screw-assisted extrusion-based additive manufacturing system. Scanning electron microscopy and x-ray microtomography was used to determine scaffold morphology. The scaffolds had high interconnectivity with regular printed fibres and pore morphologies within the designed parameters. Compressive mechanical testing showed that the addition of SMP significantly improved the compressive Young’s modulus of the scaffolds. The scaffolds were more hydrophobic with the inclusion of SMP which was linked to a decrease in total protein adsorption. Cell behaviour was assessed using human adipose derived mesenchymal stem cells. A cytotoxic effect was observed at higher particle loading (30 wt. %) after 7 days of culture. By day 21, 10 wt. % loading showed significantly higher cell metabolic activity and proliferation, high cell viability, and cell migration throughout the scaffold. Calcium mineral deposition was observed on the scaffolds during cell culture. Large calcium mineral deposits were observed at 30 wt. % and smaller calcium deposits were observed at 10 wt. %. This study demonstrates that SMPs incorporated into a PCL scaffold provided effective mechanical reinforcement, improved the rate of degradation, and increased cell proliferation, demonstrating potential suitability for bone tissue engineering applications.

• Wigen, Tove Irene & Wang, Nina Johanne (2021). Characteristics of teenagers who use dental floss. Community Dental Health.  ISSN 0265-539X. . doi: 10.1922/CDH_00006Wigen05 Fulltekst i vitenarkiv.
• Sukul, Mousumi; Sahariah, Priyanka; Lauzon, Hélène L.; Borges, João; Másson, Már; Mano, Joao F.; Haugen, Håvard Jostein & Reseland, Janne Elin (2021). In vitro biological response of human osteoblasts in 3D chitosan sponges with controlled degree of deacetylation and molecular weight. Carbohydrate Polymers.  ISSN 0144-8617.  254, s 117434 . doi: 10.1016/j.carbpol.2020.117434 Fulltekst i vitenarkiv. Vis sammendrag

  We have studied the effect of chitosan sponges, produced from chitosan batches with distinct degree of deacetylation (DDA) and molecular weight (Mw), on the adhesion, growth and differentiation of primary human osteoblasts with an aim to offer a suitable tool for guided bone regeneration. All the chitosan sponges revealed similar microstructure, irrespective of the DDA (58, 73, 82, 88, and 91 %) and Mw (749, 547, 263, 215, and 170 kDa, respectively). Cell spreading was higher on sponges having a higher DDA. Higher DDA induced a more pronounced increase in alkaline phosphatase activity, osteopontin (OPN), vascular endothelial growth factor-A (VEGF), interleukin-6 (IL-6), and reduction in monocyte chemoattractant protein-1 (MCP-1), sclerostin (SOST) and dickkopf related protein-1 as compared to lower DDA. Lower DDA induced the increased secretion of osteoprotegerin and SOST as compared to higher DDA. The combination of higher DDA and Mw induced an increased secretion of VEGF and IL-6, however reduced the secretion of OPN as compared to chitosan with similar DDA but with lower Mw. In summary, the variations in cellular responses to the different chitosan sponges indicate a potential for individual tailoring of desired responses in guided

• Colli, Maikel L.; Ramos-Rodríguez, Mireia; Nakayasu, Ernesto S.; Alvelos, Maria I.; Lopes, Miguel; Hill, Jessica L.E.; Turatsinze, Jean-Valery; Coomans de Brachène, Alexandra; Russell, Mark A.; Raurell-Vila, Helena; Castela, Angela; Juan-Mateu, Jonàs; Webb-Robertson, Bobbie-Jo M.; Krogvold, Lars; Dahl-Jørgensen, Knut; Marselli, Lorella; Marchetti, Piero; Richardson, Sarah J.; Morgan, Noel G.; Metz, Thomas O.; Pasquali, Lorenzo & Eizirik, Décio L. (2020). An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells. Nature Communications.  ISSN 2041-1723.  11:2584, s 1- 17 . doi: 10.1038/s41467-020-16327-0
• Fardal, Øystein; Skau, Irene; Rongen, Gunnar; Heasman, Peter & Grytten, Jostein Ivar (2020). Provision of treatment for periodontitis in Norway in 2013 – a national profile. International Dental Journal.  ISSN 0020-6539.  70(4), s 266- 276 . doi: 10.1111/idj.12565
• Rizk, Mumen Z.; Torgersbråten, Nina Ellen; Mohammed, Hisham; Franzen, Tanya Jeanette & Vandevska-Radunovic, Vaska (2020). Stability of single-jaw vs two-jaw surgery following the correction of skeletal class III malocclusion: A systematic review and meta-analysis. Orthodontics & craniofacial research.  ISSN 1601-6335.  s 1- 14 . doi: 10.1111/ocr.12456
• Torgersbråten, Nina Ellen; Stenvik, Arild & Espeland, Lisen Vivienne (2020). Bimaxillary surgery to correct high-angle class II malocclusion: Does a simultaneous genioplasty affect long-term stability?. European Journal of Orthodontics.  ISSN 0141-5387.  42(4), s 426- 433 . doi: 10.1093/ejo/cjz055
• Chvartszaid, David; Ellingsen, Jan Eirik; Estafanous, Emad; Huynh-Ba, Guy; Oates, Thomas; Osswald, Martin & Stanford, Clark (2020). Dental student implant education. International Journal of Oral & Maxillofacial Implants.  ISSN 0882-2786.  35(6), s 1072- 1075
• Osswald, Martin; Chvartszaid, David; Ellingsen, Jan Eirik; Estafanous, Emad; Huynh-Ba, Guy; Oates, Thomas & Stanford, Clark (2020). "The lucky fibula 2.0". International Journal of Oral & Maxillofacial Implants.  ISSN 0882-2786.  35(5), s 875- 877
• Tellefsen, Sara Julie Maria; Badian, Reza; Utheim, Tor Paaske; Utheim, Øygunn Aass; Stojanovic, Aleksandar; Tashbayev, Behzod; Ræder, Sten; Dartt, Darlene Ann & Chen, Xiangjun (2020). Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients. The ocular surface.  ISSN 1542-0124.  19, s 68- 73 . doi: 10.1016/j.jtos.2020.11.009
• Wiechmann, Dirk; Bantleon, Hans-Peter; Melsen, Birte; Zachrisson, Bjørn Uddo; Hägg, Urban; Canal, Pierre; Garcia, Robert; Barthélemi, Stephane; Frapier, Laure; Grauer, Dan; Sander, Christian; Diedrich, Peter; Jacobs, Collin; Wehrbein, Heiner; Hohoff, Ariane; Helms, Hans-Joachim & Schwestka-Polly, Rainer (2020). Incorrect measurements and misleading conclusions in the article "comparison of the efficacy of tooth alignment among lingual and labial brackets: An in vitro study". Head & Face Medicine.  ISSN 1746-160X.  16(1) . doi: 10.1186/s13005-020-00221-7
• Staxrud, Frode (2020). Minimally Invasive Dentistry. Aktuell Nordisk odontologi.  ISSN 1902-3545.  45(01), s 225- 238 . doi: 10.18261/ISSN.2058-7538-2020-01-18 Vis sammendrag

  Begrepet «Minimally Invasive Dentistry» er etter hvert godt kjent, både i Norden og Europa for øvrig. Det er allikevel viktig å minne om oss selv om de grunnleggende prinsippene i dette konseptet. Med bakgrunn i oppdatert kunnskap om karies og tannslitasje, kombinert med nyere og bedre adhesive restaureringsteknikker, er det gode muligheter for å behandle tenner på en vevsbesparende måte slik at de holder livet ut. Pasienten må settes i fokus slik at den totale behandling individualiseres. Med kjennskap til pasienten og den enkeltes særlige vilkår kan vi skreddersy en plan for hver enkelt. Forebyggelse og kontroll på risikofaktorer forut for operativ behandling og en konservativ innstilling til original tannsubstans er gode grunnleggende prinsipper.

• Halvari, Anne Elisabeth M.; Halvari, Halgeir & Deci, Edward (2020). The roles of patients' authenticity and accepting external influence, and clinicians' treatment styles in predicting patients' dental anxiety and avoidance of dental appointments. Europe's Journal of Psychology.  ISSN 1841-0413.  16(1), s 45- 61 . doi: 10.5964/ejop.v16i1.1664 Fulltekst i vitenarkiv. Vis sammendrag

  A substantial proportion of adults suffer from high dental anxiety, which is related to poor oral health and functioning. Using authenticity theory and self-determination theory, we applied a model testing two moderated mediation hypotheses: (i) the negative indirect association between authenticity and avoiding dental appointments through dental anxiety would be more evident when clinicians provides higher levels of autonomy support; and (ii) the indirect positive association between accepting external influence and avoiding dental appointments through dental anxiety would be more evident when clinicians provides higher levels of controllingness. Participants (N = 208) responded to a survey with validated questionnaires. The model with hypotheses were tested using Structural Equation Modeling (SEM) in LISREL and Conditional Process Modeling (moderated mediation). The results supported our hypotheses. The SEM model tested was found to fit the data well. Patient’s personality and dental clinic treatment environments predicted 38% of the variance in dental anxiety, which explained 38% of avoidance of treatment.

• Zou, Lai-quan; Dworschak, Annika; Alizadeh, Rafieh; Kamrawa, Seyed; Alwashahi, Mohammed; Bock, Marie; Boesveldt, Sanne; Singh, Preet Bano; Brusevold, Ingvild Johnsen; Voznessenskaya, Vera; Hummel, Thomas & Schriever, Valentin A (2020). “U-Sniff ” - the international odor identification test for children: an extension of its normative database and study of global reliability.. Rhinology.  ISSN 0300-0729.  45(7) . doi: 10.4193/Rhin19.355
• Tashbayev, Behzod; Yazdani, Mazyar; Arita, Reiko; Fineide, Fredrik & Utheim, Tor Paaske (2020). Intense pulsed light treatment in meibomian gland dysfunction: A concise review. The ocular surface.  ISSN 1542-0124.  18(4), s 583- 594 . doi: 10.1016/j.jtos.2020.06.002 Fulltekst i vitenarkiv.
• Varvin, Therese; Søftestad, Siri; Kranstad, Vibeke & Willumsen, Tiril (2020). Preparing for attack and recovering from battle: Understanding child sexual abuse survivors' experiences of dental treatment. Community Dentistry and Oral Epidemiology.  ISSN 0301-5661.  48(4), s 317- 327 . doi: 10.1111/cdoe.12536 Fulltekst i vitenarkiv.
• Magaz, Andrew; Spencer, Ben F.; Hardy, John G.; Xu, Li; Gough, Julie e. & Blaker, Jonathan James (2020). Modulation of Neuronal Cell Affinity on PEDOT−PSS Nonwoven Silk Scaffolds for Neural Tissue Engineering. ACS Biomaterials Science and Engineering.  ISSN 2373-9878. . doi: 10.1021/acsbiomaterials.0c01239 Vis sammendrag

  Peripheral nerve injury is a common consequence of trauma with low regenerative potential. Electroconductive scaffolds can provide appropriate cell growth microenvironments and synergistic cell guidance cues for nerve tissue engineering. In the present study, electrically conductive scaffolds were prepared by conjugating poly (3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT–PSS) or dimethyl sulfoxide (DMSO)-treated PEDOT–PSS on electrospun silk scaffolds. Conductance could be tuned by the coating concentration and was further boosted by DMSO treatment. Analogue NG108-15 neuronal cells were cultured on the scaffolds to evaluate neuronal cell growth, proliferation, and differentiation. Cellular viability was maintained on all scaffold groups while showing comparatively better metabolic activity and proliferation than neat silk. DMSO-treated PEDOT–PSS functionalized scaffolds partially outperformed their PEDOT–PSS counterparts. Differentiation assessments suggested that these PEDOT–PSS assembled silk scaffolds could support neurite sprouting, indicating that they show promise to be used as a future platform to restore electrochemical coupling at the site of injury and preserve normal nerve function.

• Rahmati, Maryam; Mills, David K.; Urbanska, Aleksandra M.; Saeb, Mohammad reza; Reddy Venugopal, Jayarama; RamaKrishna, Seeram & Mozafari, Masoud (2020). Electrospinning for tissue engineering applications. Progress in Materials Science.  ISSN 0079-6425.  s 1- 39 . doi: 10.1016/j.pmatsci.2020.100721 Vis sammendrag

  Tissue engineering makes use of the principles of medicine, biology and engineering and integrates them into the design of biological substitutes to restore, maintain and improve the functions of tissue. To fabricate a functional tissue, the engineered structures have to be able to mimic the extracellular matrix (ECM), provide the tissue with oxygen and nutrient circulation as well as remove metabolic wastes in the period of tissue regeneration. Continued efforts have been made in order to fabricate advanced functional three-dimensional scaffolds for tissue engineering. Electrospinning has been recognized and served as one of the most useful techniques based on the resemblance between electrospun fibers and the native tissues. Over the past few decades, a bewildering variety of nanofibrous scaffolds have been developed for various biomedical applications, such as tissue regeneration and therapeutic agent delivery. The present review aims to provide with researchers an in-depth understanding of the promising role and the practical region of applicability of electrospinning in tissue engineering and regenerative medicine by highlighting the outcomes of the most recent studies performed in this field. We address the current strategies used for improving the physicochemical interactions between the cells and the nanofibrous surface. We also discuss the progress and challenges associated with the use of electrospinning for tissue engineering and regenerative medicine applications.

• Torgersbråten, Nina Ellen; Stenvik, Arild & Espeland, Lisen Vivienne (2020). A comparison of Class II open bite correction by maxillary or mandibular surgery. American Journal of Orthodontics and Dentofacial Orthopedics.  ISSN 0889-5406.  157(5), s 631- 640 . doi: 10.1016/j.ajodo.2019.05.018
• Preus, Hans Ragnar; Al-Lami, amar Saad Abdulraheem & Baelum, Vibeke (2020). Oral hygiene revisited. The clinical effect of a prolonged oral hygiene phase prior to periodontal therapy in periodontitis patients. A randomized clinical study. Journal of Clinical Periodontology.  ISSN 0303-6979.  47(1), s 36- 42 . doi: 10.1111/jcpe.13207
• Kapralos, Vasileios; Valen, Håkon; Ørstavik, Dag; Koutroulis, Andreas; Camilleri, Josette & Sunde, Pia Titterud (2020). Antimicrobial and physicochemical characterization of endodontic sealers after exposure to chlorhexidine digluconate. Dental Materials.  ISSN 0109-5641. . doi: 10.1016/j.dental.2020.11.011
• Mauland, Erik Klepsland; Preus, Hans Ragnar & Aass, Anne Merete (2020). Comparison of commercially available 0.2% chlorhexidine mouthwash with and without anti-discoloration system: A blinded, crossover clinical trial. Journal of Clinical Periodontology.  ISSN 0303-6979.  47(12), s 1522- 1527 . doi: doi.org/10.1111/jcpe.13382 Fulltekst i vitenarkiv.
• Rizk, Mumen Z.; Torgersbråten, Nina Ellen; Mohammed, Hisham; Franzen, Tanya Jeanette & Vandevska-Radunovic, Vaska (2020). Stability of single-jaw vs two-jaw surgery following the correction of skeletal class III malocclusion: A systematic review and meta-analysis. Orthodontics & craniofacial research.  ISSN 1601-6335. . doi: DOI: 10.1111/ocr.12456
• Parma, Valentina; Ohla, Kathrin; Veldhuizen, MK; Niv, Masha Y.; Kelly, Christine E.; Bakke, Alyssa J.; Cooper, Keiland W.; Bouysset, Cedric; Pirastu, Nicola; Dibattista, Michele; Kaur, Rishemjit; Liuzza, Marco Tullio; Pepino, Marta Y.; Schöpf, Veronika; Pereda-Loth, Veronica; Olsson, Shannon B.; Gerkin, Richard C.; Dominguez, Paloma Rohlfs; Albayay, Javier; Farruggia, Michael C.; Bhutani, Surabhi; Fjaeldstad, Alexander W.; Kumar, Ritesh; Menini, Anna; Bensafi, Moustafa; Sandell, Mari; Konstantinidis, Iordanis; Di Pizio, Antonella; Genovese, Federica; Ôztürk, Lina; Thomas-Danguin, Thierry; Frasnelli, Johannes; Boesveldt, Sanne; Saatci, Ôzlem; Saraiva, Luis R.; Lin, Cailu; Golebiowski, Jerome; Hwang, Liang-Dar; Ozdener, Mehmet Hakan; Guàrdia, Maria Dolors; Laudamiel, Christophe; Ritchie, Marina; Havlicek, Jan; Pierron, Denis; Roura, Eugeni; Navarro, Marta; Nolden, Alissa A.; Lim, Juyun; Whitcroft, Katherine L.; Colquitt, Lauren R.; Singh, Preet Bano & Hayes, John E. (2020). More than smell- Covid-19 is associated with severe impairment of smell, taste, and chemethesis.. Chemical Senses.  ISSN 0379-864X.  45(7), s 609- 622 . doi: https://doi.org/10.1093/chemse/bjaa041 Fulltekst i vitenarkiv.
• Grytten, Jostein Ivar; Pervaiz, Maryam; Rongen, Gunnar & Skau, Irene (2020). De unge voksnes tannhelse - hvor stort er deres behandlingsbehov? En analyse av studenter som var pasienter hos SiO Helse Tannlege i perioden 2007-2018. Den norske tannlegeforenings tidende.  ISSN 0029-2303.  130, s 904- 912
• Fardal, Øystein; Skau, Irene; Rongen, Gunnar; Heasman, Peter & Grytten, Jostein Ivar (2020). Treatment provision of periodontal diseases in Norway in 2013 - a national profile.. International Dental Journal.  ISSN 0020-6539.  70(4), s 266- 276 . doi: https://doi.org/10.1111/idj.12565 Fulltekst i vitenarkiv.
• Hvaring, Christina & Birkeland, Kari (2020). The long-term fate of persisting deciduous molars and canines in 42 patients with severe hypodontia: a 12-year follow-up. European Journal of Orthodontics.  ISSN 0141-5387.  42(6), s 581- 586 . doi: https://doi.org/10.1093/ejo/cjz090
• Hamran, Tord & Vandevska-Radunovic, Vaska (2020). Bruk av skinner innen tannregulering. Aktuell Nordisk odontologi.  ISSN 1902-3545.  45, s 153- 165 . doi: DOI: HTTPS://DOI.ORG/10.18261/ISSN.2058-7538-2020-01-13
• Bjering, Ragnar & Vandevska-Radunovic, Vaska (2020). Hvor stabil er kjeveortopedisk behandling på sikt, og hvilken betydning har retainere?. Aktuell Nordisk odontologi.  ISSN 1902-3545.  45, s 166- 178 . doi: DOI: HTTPS://DOI.ORG/10.18261/ISSN.2058-7538-2020-01-14
• Hugo, Jørgen; Koldsland, Odd Carsten; Aass, Anne Merete & Tiainen, Hanna (2020). Development and initial testing of an in vitro model simulating class II furcation defects. Clinical and Experimental Dental Research.  ISSN 2057-4347. . doi: 10.1002/cre2.346 Fulltekst i vitenarkiv.
• Koldsland, Odd Carsten & Aass, Anne Merete (2020). Supportive treatment following peri-implantitis surgery: An RCT using titanium curettes or chitosan brushes. Journal of Clinical Periodontology.  ISSN 0303-6979.  47(10), s 1259- 1267 . doi: 10.1111/jcpe.13357 Fulltekst i vitenarkiv.
• Vetyskova, Veronika; Zouharova, Monika; Bednarova, Lucie; Vaněk, Ondřej; Sázelová, Petra; Kašička, Václav; Vymetal, Jiri; Srp, Jaroslav; Rumlová, Michaela; Charnavets, Tatsiana; Postulkova, Klara; Reseland, Janne Elin; Bousova, Kristyna & Vondrasek, Jiri (2020). Characterization of AMBN I and II isoforms and study of their Ca2+ binding properties. International Journal of Molecular Sciences.  ISSN 1422-0067.  21, s 9293 . doi: 10.3390/ijms21239293 Fulltekst i vitenarkiv.
• Zhu, Hao; Blahnová, Veronika Hefka; Perale, Giuseppe; Xiao, Jun; Betge, Felice; Boniolo, Fabio; Filová, Eva; Lyngstadaas, Ståle Petter & Haugen, Håvard Jostein (2020). Xeno-Hybrid Bone Graft Releasing Biomimetic Proteins Promotes Osteogenic Differentiation of hMSCs. Frontiers in Cell and Developmental Biology.  ISSN 2296-634X. . doi: 10.3389/fcell.2020.619111 Fulltekst i vitenarkiv.
• Tashbayev, Behzod; Utheim, Tor Paaske; Utheim, Øygunn Aass; Ræder, Sten; Jensen, Janicke Cecilie Liaaen; Yazdani, Mazyar; Lagali, Neil Satish; Vitelli, Valeria; Dartt, Darlene Ann & Chen, Xiangjun (2020). Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease. Scientific Reports.  ISSN 2045-2322.  s 1- 7 . doi: 10.1038/s41598-020-62583-x Fulltekst i vitenarkiv.
• Brennhovd, Anders; Petrovski, Beata & Hjortsjö, Carl (2020). Benoppbygging før implantatinnsetting – overlevelse og suksess. Den norske tannlegeforenings tidende.  ISSN 0029-2303.  130(10), s 796- 805
• Seitz, Elke; Hjortsjö, Carl; Dahl, Jon Einar & Saxegaard, Erik (2020). Dentin to dentin adhesion using combinations of resin cements and adhesives from different manufacturers - a novel approach. Biomaterial Investigations in Dentistry.  7(1), s 96- 104 . doi: 10.1080/26415275.2020.1793677 Fulltekst i vitenarkiv.
• Thorlacius, Gudny Ella; Hultin-Rosenberg, Lina; Sandling, Johanna K.; Bianchi, Matteo; Imgenberg-Kreuz, Juliana; Pucholt, Pascal; Theander, Elke; Kvarnström, Marika; Forsblad-d’Elia, Helena; Bucher, Sara Magnusson; Norheim, Katrine Brække; Johnsen, Svein Joar Auglænd; Hammenfors, Sten Daniel; Skarstein, Kathrine; Jonsson, Malin V; Bäcklund, Eva; Aqrawi, Lara A.; Jensen, Janicke Liaaen; Palm, Øyvind; Morris, Andrew P.; consortium, the DISSECT; meadows, jennifer r; Rantapää-Dahlqvist, Solbritt; Mandl, Thomas; Eriksson, Per; Lind, Lars; Omdal, Roald; Jonsson, Sten Ture Roland; Lindblad-Toh, Kerstin; Rönnblom, Lars; Wahren-Herlenius, Marie & Nordmark, Gunnel (2020). Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome. Rheumatology.  ISSN 1462-0324. . doi: 10.1093/rheumatology/keaa367
• Weber, Florian; Sagstuen, Einar; Zhong, Qi-Zhi; Zheng, Tian & Tiainen, Hanna (2020). Tannic Acid Radicals in the Presence of Alkali Metal Salts and Their Impact on the Formation of Silicate-Phenolic Networks. ACS Applied Materials & Interfaces.  ISSN 1944-8244.  12(47), s 52457- 52466 . doi: 10.1021/acsami.0c16946 Fulltekst i vitenarkiv.
• Kallas, Pawel; Haugen, Håvard Jostein; Gadegaard, Nikolaj; Stormonth-Darling, John; Hulander, Mats; Andersson, Martin & Valen, Håkon (2020). Adhesion of Escherichia Coli to Nanostructured Surfaces and the Role of Type 1 Fimbriae. Nanomaterials.  ISSN 2079-4991.  10(11), s 2247 . doi: 10.3390/nano10112247 Fulltekst i vitenarkiv. Vis sammendrag

  Bacterial fimbriae are an important virulence factor mediating adhesion to both biotic and abiotic surfaces and facilitating biofilm formation. The expression of type 1 fimbriae of Escherichia coli is a key virulence factor for urinary tract infections and catheter-associated urinary tract infections, which represent the most common nosocomial infections. New strategies to reduce adhesion of bacteria to surfaces is therefore warranted. The aim of the present study was to investigate how surfaces with different nanotopography-influenced fimbriae-mediated adhesion. Surfaces with three different nanopattern surface coverages made in polycarbonate were fabricated by injection molding from electron beam lithography nanopatterned templates. The surfaces were constructed with features of approximately 40 nm width and 25 nm height with 100 nm, 250 nm, and 500 nm interspace distance, respectively. The role of fimbriae type 1-mediated adhesion was investigated using the E. coli wild type BW25113 and ΔfimA (with a knockout of major pilus protein FimA) and ΔfimH (with a knockout of minor protein FimH) mutants. For the surfaces with nanotopography, all strains adhered least to areas with the largest interpillar distance (500 nm). For the E. coli wild type, no difference in adhesion between surfaces without pillars and the largest interpillar distance was observed. For the deletion mutants, increased adhesion was observed for surfaces without pillars compared to surfaces with the largest interpillar distance. The presence of a fully functional type 1 fimbria decreased the bacterial adhesion to the nanopatterned surfaces in comparison to the mutants.

• Øyri, Hauk Furnes; Jensen, Janicke Liaaen; Barkvoll, Pål; Jonsdottir, Olga Hrønn; Reseland, Janne Elin & Bjørnland, Tore (2020). Incidence of alveolar osteitis after mandibular third molar surgery. Can inflammatory cytokines be identified locally?. Acta Odontologica Scandinavica.  ISSN 0001-6357.  s 1- 7 Fulltekst i vitenarkiv.
• Fidalgo, Gabriel; Paiva, Katrine; Mendes, Gabriela; Barcellos, Renan; Colaço, Gustavo; Sena, Gabriela; Pickler, Arissa; Mota, Carla Lemos; Tromba, Giuliana; Nogueira, Liebert Parreiras; Braz, Delson; Silva, H; Colaço, Marcos & Barroso, Regina C. (2020). Synchrotron microtomography applied to the volumetric analysis of internal structures of Thoropa miliaris tadpoles. Scientific Reports.  ISSN 2045-2322.  10 . doi: 10.1038/s41598-020-75993-8 Fulltekst i vitenarkiv. Vis sammendrag

  Amphibians are models for studying applied ecological issues such as habitat loss, pollution, disease, and global climate change due to their sensitivity and vulnerability to changes in the environment. Developmental series of amphibians are informative about their biology, and X-ray based 3D reconstruction holds promise for quantifying morphological changes during growth—some with a direct impact on the possibility of an experimental investigation on several of the ecological topics listed above. However, 3D resolution and discrimination of their soft tissues have been difficult with traditional X-ray computed tomography, without time-consuming contrast staining. Tomographic data were initially performed (pre-processing and reconstruction) using the open-source software tool SYRMEP Tomo Project. Data processing and analysis of the reconstructed tomography volumes were conducted using the segmentation semi-automatic settings of the software Avizo Fire 8, which provide information about each investigated tissues, organs or bone elements. Hence, volumetric analyses were carried out to quantify the development of structures in different tadpole developmental stages. Our work shows that synchrotron X-ray microtomography using phase-contrast mode resolves the edges of the internal tissues (as well as overall tadpole morphology), facilitating the segmentation of the investigated tissues. Reconstruction algorithms and segmentation software played an important role in the qualitative and quantitative analysis of each target structure of the Thoropa miliaris tadpole at different stages of development, providing information on volume, shape and length. The use of the synchrotron X-ray microtomography setup of the SYRMEP beamline of Elettra Synchrotron, in phase-contrast mode, allows access to volumetric data for bone formation, eye development, nervous system and notochordal changes during the development (ontogeny) of tadpoles of a cycloramphid frog Thoropa miliaris. As key elements in the normal development of these and any other frog tadpole, the application of such a comparative ontogenetic study, may hold interest to researchers in experimental and environmental disciplines.

• Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E.; Licata, Giada; Krogvold, Lars; Marselli, Lorella; Gysemans, Conny; Overbergh, Lut; Marchetti, Piero; Mathieu, Chantal; Dahl-Jørgensen, Knut; Sebastiani, Guido & Dotta, Francesco (2020). Pancreatic alpha-cells contribute together with beta-cells to CXCL10 expression in type 1 diabetes. Frontiers in Endocrinology.  ISSN 1664-2392.  11:630, s 1- 13 . doi: 10.3389/fendo.2020.00630 Fulltekst i vitenarkiv.
• Hesse, Juliane; Schmalfuss, Andreas Jörn & Kvaal, Sigrid Ingeborg (2020). Photodynamic therapy of oral lichen planus. Photochemical and Photobiological Sciences.  ISSN 1474-905X.  19, s 1271- 1279 . doi: 10.1039/d0pp00249f
• Gross, Karlis Agris; Petzold, Christiane; Pluduma, Liene; Kumermanis, Maris & Haugen, Håvard Jostein (2020). Structural and Chemical Hierarchy in Hydroxyapatite Coatings. Materials.  ISSN 1996-1944.  13(4447), s 1- 15 Fulltekst i vitenarkiv. Vis sammendrag

  Hydroxyapatite coatings need similarly shaped splats as building blocks and then a homogeneous microstructure to unravel the structural and chemical hierarchy for more refined improvements to implant surfaces. Coatings were thermally sprayed with differently sized powders (20-40, 40-63 and 63-80 µm) to produce flattened homogeneous splats. The surface was characterized for splat shape by profilometry and AFM, crystal size by AFM, crystal orientation by X-ray diffraction (XRD) and structural variations by XRD. Chemical composition was assessed by phase analysis, but variations in chemistry were detected by XRD and Raman spectroscopy. The resulting surface electrical potential was measured by Kelvin probe AFM. Five levels of structural hierarchy were suggested: the coating, the splat, oriented crystals, alternate layers of oxyapatite and HAp, and the suggested anion orientation. Chemical hierarchy was present over a lower range of order for smaller splats. Coatings made from smaller splats exhibited a greater electrical potential, inferred to arise from oxyapatite, and supplemented by ordered OH- ions in a rehydroxylated surface layer. A model has been proposed to show the influence of structural hierarchy on the electrical surface potential. Structural hierarchy is proposed as a means to further refine the properties of implant surfaces.

• Tulek, Amela; Mulic, Aida; Stenhagen, Kjersti Refsholt; Galtung, Hilde; Saeed, Muhammad; Utheim, Tor Paaske; Khuu, Cuong; Galteland, Pål & Sehic, Amer (2020). Dental Erosion in Mice with Impaired Salivary Gland Function. Acta Odontologica Scandinavica.  ISSN 0001-6357.  78, s 1- 11 . doi: 10.1080/00016357.2020.1734234 Fulltekst i vitenarkiv.
• Aqrawi, Lara A.; Chen, Xiangjun; Hynne, Håvard; Amdal, Cecilie Delphin; Reppe, Sjur; Aass, Hans Christian Dalsbotten; Rykke, Morten; Hove, Lene Hystad; Young, Alix; Herlofson, Bente Brokstad; Westgaard, Kristine Løken; Utheim, Tor Paaske; Galtung, Hilde & Jensen, Janicke Liaaen (2020). Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways. Cells.  ISSN 2073-4409.  9(9) . doi: 10.3390/cells9092050 Fulltekst i vitenarkiv.
• Bunæs, Dagmar; Verket, Anders; Aass, Anne Merete & Bolstad, Anne Isine (2020). Tyypin 2 diabeteksen ja parodontaalisairauksien välinen yhteys. Suomen hammaslaakarilehti.  ISSN 0355-4090.  3, s 24- 29
• Haugen, Håvard Jostein; Qasim, Syed Saad Bin; Matinlinna, Jukka P; Vallittu, Pekka K. & Nogueira, Liebert Parreiras (2020). Nano-CT as tool for characterization of dental resin composites. Scientific Reports.  ISSN 2045-2322.  10 . doi: 10.1038/s41598-020-72599-y Fulltekst i vitenarkiv. Vis sammendrag

  Technological advances have made it possible to examine dental resin composites using 3D nanometer resolution. This investigation aims to characterize existing dental nano-hybrid and micro-hybrid resin composites through comparing and contrasting nano-computed tomography (nano-CT) with micro-CT and high-resolution SEM images. Eight commercially available and widely used dental resin composites, 2 micro-hybrid and 6 nano-hybrid were researched. Cured samples were examined and characterized using nano-CT (resolution 450 nm) and compared with micro-CT images (resolution 2 µm). Acquired images were reconstructed and image analysis was carried out to determine porosity and pore morphology. A comprehensive comparison of scanning micrograph images unsurprisingly revealed that the nano-CT images displayed greater detail of the ultrastructure of cured dental resin composites. Filler particle diameters and its volumes were lower when measured using nano-CT, porosity being higher where analysed at higher resolution. There were large variations between the examined materials. Fewer voids were found in Tetric EvoCeram and IPS Empress Direct, the smallest pores being found in Universal XTE and Tetric EvoCeram. Nano-CT was successfully used to investigate the morphology of dental resin composites and showed that micro-CT gives a lower porosity and pore size but overestimates filler particle size. There were large discrepancies between the tested composites. Evidence of porosities and pores within a specimen is a critical finding and it might have a detrimental effect on a material’s clinical performance.

• Magaz, Adrian; Ashton, Mark; Hathout, Rania; Li, Xu; Hardy, John & Blaker, Jonny J. (2020). Electroresponsive silk-based biohybrid composites for electrochemically controlled growth factor delivery. Pharmaceutics.  ISSN 1999-4923.  12(8), s 1- 12 . doi: 10.3390/pharmaceutics12080742 Fulltekst i vitenarkiv.
• Skallevold, Hans Erling & Verket, Anders (2020). Myasthenia gravis og orale utfordringer. Den norske tannlegeforenings tidende.  ISSN 0029-2303.  130(8), s 614- 617
• Ellingsen, Jan Eirik; Chvartszaid, David; Estafanous, Emad; Huynh-Ba, Guy; Oates, Thomas; Osswald, Martin & Stanford, Clark (2020). Impact of Tobacco Smoking on Peri-implantitis. International Journal of Oral & Maxillofacial Implants.  ISSN 0882-2786.  35(4), s 671- 673
• Oates, Thomas; Ellingsen, Jan Eirik; Chvartszaid, David; Huynh-Ba, Guy; Estafanous, Emad; Osswald, Martin & Stanford, Clark (2020). Enhancing Implant Stability with Osseodensification: Remember That Biology Happens!. International Journal of Oral & Maxillofacial Implants.  ISSN 0882-2786.  35(3), s 457- 460
• Huynh-Ba, Guy; Estafanous, Emad; Ellingsen, Jan Eirik; Oates, Thomas; Osswald, Martin; Chvartszaid, David & Stanford, Clark (2020). Antibiotics and Implant Therapy Revisited. International Journal of Oral & Maxillofacial Implants.  ISSN 0882-2786.  35(2), s 244- 247
• Estafanous, Emad; Chvartszaid, David; Ellingsen, Jan Eirik; Huynh-Ba, Guy; Oates, Thomas; Osswald, Martin & Stanford, Clark (2020). Effect of Medications/Chemotherapy on Osseointegration. International Journal of Oral & Maxillofacial Implants.  ISSN 0882-2786.  35(1), s 15- 21

Se alle arbeider i Cristin

• Jensen, Janicke Liaaen (2021, 25. februar). Mye kunnskap om sjeldenhet. [Fagblad].  Nor Tannlegeforen Tid.
• Jensen, Janicke Liaaen (2021, 25. februar). God tannhelse = god helse i fremtiden. [Tidsskrift].  Tara.
• Jensen, Janicke Liaaen (2021). Sammenhengen mellom oral og generell helse.
• Sjilov, Axel; Gustafsson, Miriam K. & Syversen, Unni (2020). Should we be concerned about the vitamin A status among Norwegian pregnant women?.
• Diep, My Tien; Jensen, Janicke Liaaen; Sødal, Anne Thea Tveit; Young, Alix; Skudutyte-Rysstad, Rasa & Hove, Lene Hystad (2020). Are Xerostomia and Hyposalivation Common Problems Among 65-Year-Olds?. Caries Research.  ISSN 0008-6568.  54(4), s 449- 450 . doi: 10.1159/000511860
• Weber, Florian; Sagstuen, Einar & Tiainen, Hanna (2020). Chemistry of Silica-Phenolic Networks.
• Skaare, Anne B; Herlofson, Bente Brokstad & Søland, Tine Merete (2020). Orofacial granulomatose og Crohns sykdom – et klinisk kasus og en litteraturgjennomgang. Den norske tannlegeforenings tidende.  ISSN 0029-2303.  130(11), s 914- 920
• Sødal, Anne Thea Tveit; Singh, Preet Bano; Diep, My Tien & Hove, Lene Hystad (2020). Prevalence of Smell, Taste, Trigeminal Disorders and Quality of Life Among 65-Year-Olds in Oslo. Caries Research.  ISSN 0008-6568.  54(4), s 449- 449 . doi: 10.1159/000511860
• Herlofson, Bente Brokstad (2020). Pasienter på benmodulerende behandling og osteonekrose - med fokus på myelomatose.
• Herlofson, Bente Brokstad (2020). Jaw osteomyelitis/osteonecrosis - clinical presentation, diagnosis, therapy.
• Steffensen, Inger-Lise; Alexander, Jan; Binderud, Mona-Lise; Bruzell, Ellen Merete; Dahl, Knut Helkås; Granum, Berit; Herlofson, Bente Brokstad; Hetland, Ragna Bogen; Husøy, Trine; Paulsen, Jan Erik; Rohloff, Jens; Thrane, Vibeke & Wicklund, Trude (2020). Risk assessments of aspartame, acesulfame K, sucralose and benzoic acid from soft drinks, "saft", nectar and flavoured water. European Journal of Nutrition and Food Safety.  ISSN 2347-5641.  12(8), s 66- 68 . doi: 10.9734/EJNFS72020/v12i830265
• Herlofson, Bente Brokstad (2020). Kreftpasienter på antiresorptiv behandling med risiko for utvikling av osteonekrose i kjevene.
• Herlofson, Bente Brokstad (2020). Pasienter på benmodulerende behandling og osteonekrose.
• Qasim, Syed Saad Bin; Nogueira, Liebert Parreiras; Fawzy, Amr S. & Daood, Umer (2020). Correction to: the Effect of Cross-Linking Efficiency of Drug-Loaded Novel Freeze Gelated Chitosan Templates for Periodontal Tissue Regeneration (AAPS PharmSciTech, (2020), 21, 5, (173), 10.1208/s12249-020-01708-x). AAPS PharmSciTech.  ISSN 1530-9932.  21(7) . doi: 10.1208/s12249-020-01778-x
• Jensen, Janicke Liaaen (2020). Integrated oral and general health.
• Jensen, Janicke Liaaen (2020). Eldres munnehelse går under radaren. forskning.no.
• Jensen, Janicke Liaaen (2020). Hvordan påvirker revmatiske sykdommer generelt, og Sjögrens syndrom spesielt, oral helse?.
• Suslu, Safiyye; Høgestøl, Ingvild Kristine; Eriksen, Erik Fink & Reseland, Janne Elin (2020). Changes in protein profile in bone marrow extracts before and one year after gastric bypass surgery. Bone Reports.  ISSN 2352-1872.  13 . doi: https://doi.org/10.1016/j.bonr.2020.100368
• Skoglund, Lasse Ansgar (2020). NTFs nye obligatoriske etterutdanning: Svar til Sigbjørn Løes. Den norske tannlegeforenings tidende.  ISSN 0029-2303.  130(9)
• Skoglund, Lasse Ansgar (2020). NTFs nye obligatoriske etterutdanning: En liten kommentar. Den norske tannlegeforenings tidende.  ISSN 0029-2303.  130, s 734- 735

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