Siste publikasjoner

• Huynh, T.T.M.; Aass, Hans Christian Dalsbotten; Falk, Ragnhild Sørum; Astrup, Guro Lindviksmoen; Helland, Åslaug & Bjøro, Trine [Vis alle 14 forfattere av denne artikkelen] (2022). Associations between patient-reported late effects and systemic cytokines in long-term survivors of head and neck cancer treated with radiotherapy. Journal of cancer survivorship. ISSN 1932-2259. doi: 10.1007/s11764-022-01273-1.
• Tanem, Kristine Eidal; Stensvold, Einar; Wilberg, Petter; Skaare, Anne B; Brandal, Petter & Herlofson, Bente Brokstad (2022). Oral and dental late effects in long-term survivors of childhood embryonal brain tumors. Supportive Care in Cancer. ISSN 0941-4355. s. 1–9. doi: 10.1007/s00520-022-07405-8.
• Lein, Ingvild Årøen; Bjørnland, Tore & Loro, Lado Lako (2022). Retrospective Study of Orbital and Orbitozygomaticomaxillary Complex Factures Treated at Aalesund Hospital Between 2002 and 2017. Craniomaxillofacial Trauma & Reconstruction. ISSN 1943-3875. s. 1–9. doi: 10.1177/19433875221135932.
• Lundtoft, Christian; Pucholt, Pascal; Martin, Myriam; Bianchi, Matteo; Lundström, Emeli & Eloranta, Maija-Leena [Vis alle 43 forfattere av denne artikkelen] (2022). Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases. Arthritis & Rheumatology. ISSN 2326-5191. 74(8), s. 1440–1450. doi: 10.1002/art.42122. Fulltekst i vitenarkiv
• Khatri, Bhuwan; Tessneer, Kandice L.; Rasmussen, Astrid; Aghakhanian, Farhang; Reksten, Tove Ragna & Adler, Adam [Vis alle 66 forfattere av denne artikkelen] (2022). Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells. Nature Communications. ISSN 2041-1723. 13(1), s. 1–17. doi: 10.1038/s41467-022-30773-y. Fulltekst i vitenarkiv
• Krüger, Tormod Bjartveit; Syversen, Unni; Herlofson, Bente Brokstad; Lian, Aina-Mari & Reseland, Janne Elin (2022). Targeting a therapeutically relevant concentration of alendronate for in vitro studies on osteoblasts. Acta Odontologica Scandinavica. ISSN 0001-6357. doi: 10.1080/00016357.2022.2072522.
• Frigaard, Julie Mari; Jensen, Janicke Liaaen; Galtung, Hilde & Hiorth, Marianne (2022). The Potential of Chitosan in Nanomedicine: An Overview of the Cytotoxicity of Chitosan Based Nanoparticles. Frontiers in Pharmacology. ISSN 1663-9812. 13, s. 1–19. doi: 10.3389/fphar.2022.880377.
• Hynne, Håvard; Tashbayev, Behzod; Diep, My Tien; Sødal, Anne Thea Tveit; Badian, Reza A. & Chen, Xiangjun [Vis alle 10 forfattere av denne artikkelen] (2022). The relationship between ocular and oral dryness in a cohort from the 65-year-old population in Norway. Scientific Reports. ISSN 2045-2322. 12(1). doi: 10.1038/s41598-022-13985-6. Fulltekst i vitenarkiv
• Tanem, Kristine Eidal; Wilberg, Petter; Diep, Phoi Phoi; Ruud, Ellen; Skaare, Anne B & Brinch, Lorentz [Vis alle 7 forfattere av denne artikkelen] (2022). Oral chronic GVHD after allogeneic stem cell transplantation without total body irradiation performed at a young age. Supportive Care in Cancer. ISSN 0941-4355. 30(5), s. 4121–4128. doi: 10.1007/s00520-022-06836-7.
• Tanem, Kristine Eidal; Stensvold, Einar; Wilberg, Petter; Skaare, Anne B; Singh, Preet Bano & Brandal, Petter [Vis alle 7 forfattere av denne artikkelen] (2022). Taste and smell function in long-term survivors after childhood medulloblastoma/CNS-PNET. Supportive Care in Cancer. ISSN 0941-4355. 30, s. 6155–6162. doi: 10.1007/s00520-022-07048-9. Fulltekst i vitenarkiv
• Singer, Susanne; Hammerlid, Eva; Tomaszewska, Iwona M; Amdal, Cecilie Delphin; Bjordal, Kristin & Herlofson, Bente Brokstad [Vis alle 31 forfattere av denne artikkelen] (2021). Methodological approach for determining the Minimal Important Difference and Minimal Important Change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the Swallowing scale. Quality of Life Research. ISSN 0962-9343. doi: 10.1007/s11136-021-02939-6.
• Yazdani, Mazyar; Fiskådal, Jørgen; Chen, Xiangjun; Utheim, Øygunn Aass; Ræder, Sten & Vitelli, Valeria [Vis alle 7 forfattere av denne artikkelen] (2021). Tear film break-up time and dry eye disease severity in a large norwegian cohort. Journal of Clinical Medicine. ISSN 2077-0383. 10(4), s. 1–16. doi: 10.3390/jcm10040884. Fulltekst i vitenarkiv
• Samuelsen, Tea Marie B; Aqrawi, Lara A.; Skarstein, Kathrine & Jensen, Janicke Liaaen (2021). Evaluering av spyttkjertelbiopsier ved utredning av Sjögrens syndrom. Den norske tannlegeforenings tidende. ISSN 0029-2303. 131, s. 988–994.
• Ehrenstein, Vera; Heide-Jørgensen, Uffe; Schiødt, Morten; Akre, Olof; Herlofson, Bente Brokstad & Hansen, Svein [Vis alle 13 forfattere av denne artikkelen] (2021). Osteonecrosis of the jaw among patients with cancer treated with denosumab or zoledronic acid: Results of a regulator-mandated cohort postauthorization safety study in Denmark, Norway, and Sweden. Cancer. ISSN 0008-543X. doi: 10.1002/cncr.33802. Fulltekst i vitenarkiv
• Chen, Xiangjun; Badian, Reza; Hynne, Håvard; Amdal, Cecilie Delphin; Herlofson, Bente Brokstad & Utheim, Øygunn Aass [Vis alle 10 forfattere av denne artikkelen] (2021). Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer. Scientific Reports. ISSN 2045-2322. 11:22419, s. 1–7. doi: 10.1038/s41598-021-01844-9. Fulltekst i vitenarkiv
• Yazdani, Mazyar; Elgstøen, Katja Benedikte Prestø & Utheim, Tor Paaske (2021). Eye Make-up Products and Dry Eye Disease: A Mini Review. Current Eye Research. ISSN 0271-3683. s. 1–11. doi: 10.1080/02713683.2021.1966476.
• Tulek, Amela; Mulic, Aida; Runningen, Maria; Lillemo Diesen, Jannike; Utheim, Tor Paaske & Khan, Qalbi [Vis alle 7 forfattere av denne artikkelen] (2021). Genetic Aspects of Dental Erosive Wear and Dental Caries. International Journal of Dentistry. ISSN 1687-8728. 2021. doi: 10.1155/2021/5566733. Fulltekst i vitenarkiv
• Fineide, Fredrik; Chen, Xiangjun; Bjellaas, Thomas; Vitelli, Valeria; Utheim, Tor Paaske & Jensen, Janicke Liaaen [Vis alle 7 forfattere av denne artikkelen] (2021). Characterization of lipids in saliva, tears and minor salivary glands of sjögren’s syndrome patients using an hplc/ms‐based approach. International Journal of Molecular Sciences. ISSN 1661-6596. 22(16). doi: 10.3390/ijms22168997. Fulltekst i vitenarkiv
• Sødal, Anne Thea Tveit; Singh, Preet Bano; Skudutyte-Rysstad, Rasa; Diep, My Tien & Hove, Lene Hystad (2021). Smell, taste and trigeminal disorders in a 65-year-old population. BMC Geriatrics. ISSN 1471-2318. doi: 10.1186/s12877-021-02242-6. Fulltekst i vitenarkiv
• Riutord-Sbert, Pere; Pereira, Thais Christina; de Pedro-Gomez, Joan Ernest; Gonzales-Carrasco, Diego; Lopez-Gonzalez, Angel Arturo & Barkvoll, Pål (2021). Study of the use of a personalized peripheral sealing device on surgical face masks in high-risk situations against COVID-19. PLOS ONE. ISSN 1932-6203. doi: 10.1371/journal.pone.0253382. Fulltekst i vitenarkiv
• Matri, Kristine Lindstad & Jensen, Janicke Liaaen (2021). Kirurgisk behandling av retinert andre molar i underkjeven. En retrospektiv studie. Den norske tannlegeforenings tidende. ISSN 0029-2303. 131, s. 358–366.
• Dela Cruz, Ariana; Kartha, Vinay; Tilston-Lunel, Andrew; Mi, Rongjuan; Reynolds, Taylor L. & Mingueneau, Michael [Vis alle 11 forfattere av denne artikkelen] (2021). Gene expression alterations in salivary gland epithelia of Sjögren’s syndrome patients are associated with clinical and histopathological manifestations. Scientific Reports. ISSN 2045-2322. 11, s. 1–12. doi: 10.1038/s41598-021-90569-w. Fulltekst i vitenarkiv
• Westgaard, Kristine Løken; Hynne, Håvard; Amdal, Cecilie Delphin; Young, Alix; Singh, Preet Bano & Chen, Xiangjun [Vis alle 12 forfattere av denne artikkelen] (2021). Oral and ocular late effects in head and neck cancer patients treated with radiotherapy. Scientific Reports. ISSN 2045-2322. 11:4026, s. 1–11. doi: 10.1038/s41598-021-83635-w. Fulltekst i vitenarkiv
• Kruger, Tormod Bjartveit; Herlofson, Bente Brokstad; Lian, Aina-Mari; Syversen, Unni & Reseland, Janne Elin (2021). Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts. Bone Reports. ISSN 2352-1872. 14:100750, s. 1–7. doi: 10.1016/j.bonr.2021.100750. Fulltekst i vitenarkiv
• Diep, My Tien; Jensen, Janicke Liaaen; Skudutyte-Rysstad, Rasa; Young, Alix; Sødal, Anne Thea Tveit & Petrovski, Beata [Vis alle 7 forfattere av denne artikkelen] (2021). Xerostomia and hyposalivation among a 65-yr-old population living in Oslo, Norway. European Journal of Oral Sciences. ISSN 0909-8836. 129(1), s. 1–11. doi: 10.1111/eos.12757. Fulltekst i vitenarkiv
• Kise, Yoshitaka; Møystad, Anne; Bjørnland, Tore; Shimizu, Mayumi; Ariji, Yoshiko & Kuwada, Chiaki [Vis alle 10 forfattere av denne artikkelen] (2021). Effects of 1 year training on the performance of ultrasonographic image interpretation: A preliminary evaluation using images of Sjogren syndrome patients. Imaging Science in Dentistry. ISSN 2233-7822. doi: 10.5624/isd.20200294. Fulltekst i vitenarkiv
• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Fjeld, Katrine Gahre; Hove, Lene Hystad & Malterud, Karl Egil [Vis alle 11 forfattere av denne artikkelen] (2021). A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: A randomized controlled trial. Supportive Care in Cancer. ISSN 0941-4355. doi: 10.1007/s00520-021-06021-2. Fulltekst i vitenarkiv Vis sammendrag

  Background: Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. Aim: This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. Design: A block-randomized controlled trial. Data were collected before and after a 4-day intervention with either SO (n=44) or NS (n=44). Numerical rating scales (NRS, 0-10) and 12 items from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Oral Health 17 (EORTC QLQ-OH17) measured patient-reported oral symptoms. An oral examination was performed before and after the intervention. Setting/participants: This study included adult patients with late-stage cancer in an inpatient hospice unit. Results: Of the 88 patients included (mean age=63.9 years, SD=10.6), 73 (83%) completed the study. At baseline, 78% reported dry mouth on the EORTC QLQ-OH17, and 80% rated dry mouth ≥4 on the NRS. Total oral health scores based on the 12 EORTC QLQ-OH17 items improved similarly in both groups (p

• Gerkin, Richard C; Ohla, Kathrin; Veldhuizen, Marie G; Joseph, Paule V; Kelly, Christine E & Bakke, Alyssa J [Vis alle 71 forfattere av denne artikkelen] (2021). Recent smell loss is the best predictor of COVID-19 among individuals with recent respiratory symptoms. . Chemical Senses. ISSN 0379-864X. doi: 10.1093/chemse/bjaa081.
• Tellefsen, Sara Julie Maria; Badian, Reza; Utheim, Tor Paaske; Utheim, Øygunn Aass; Stojanovic, Aleksandar & Tashbayev, Behzod [Vis alle 9 forfattere av denne artikkelen] (2020). Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients. The ocular surface. ISSN 1542-0124. 19, s. 68–73. doi: 10.1016/j.jtos.2020.11.009.
• Zou, Lai-quan; Dworschak, Annika; Alizadeh, Rafieh; Kamrawa, Seyed; Alwashahi, Mohammed & Bock, Marie [Vis alle 12 forfattere av denne artikkelen] (2020). “U-Sniff ” - the international odor identification test for children: an extension of its normative database and study of global reliability. . Rhinology. ISSN 0300-0729. 45(7). doi: 10.4193/Rhin19.355.
• Tashbayev, Behzod; Yazdani, Mazyar; Arita, Reiko; Fineide, Fredrik & Utheim, Tor Paaske (2020). Intense pulsed light treatment in meibomian gland dysfunction: A concise review. The ocular surface. ISSN 1542-0124. 18(4), s. 583–594. doi: 10.1016/j.jtos.2020.06.002. Fulltekst i vitenarkiv
• Parma, Valentina; Ohla, Kathrin; Veldhuizen, MK; Niv, Masha Y.; Kelly, Christine E. & Bakke, Alyssa J. [Vis alle 52 forfattere av denne artikkelen] (2020). More than smell- Covid-19 is associated with severe impairment of smell, taste, and chemethesis. Chemical Senses. ISSN 0379-864X. 45(7), s. 609–622. doi: 10.1093/chemse/bjaa041. Fulltekst i vitenarkiv
• Tashbayev, Behzod; Utheim, Tor Paaske; Utheim, Øygunn Aass; Ræder, Sten; Jensen, Janicke Cecilie Liaaen & Yazdani, Mazyar [Vis alle 10 forfattere av denne artikkelen] (2020). Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease. Scientific Reports. ISSN 2045-2322. s. 1–7. doi: 10.1038/s41598-020-62583-x. Fulltekst i vitenarkiv
• Thorlacius, Gudny Ella; Hultin-Rosenberg, Lina; Sandling, Johanna K.; Bianchi, Matteo; Imgenberg-Kreuz, Juliana & Pucholt, Pascal [Vis alle 32 forfattere av denne artikkelen] (2020). Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome. Rheumatology. ISSN 1462-0324. 60(2), s. 837–848. doi: 10.1093/rheumatology/keaa367.
• Øyri, Hauk Furnes; Jensen, Janicke Liaaen; Barkvoll, Pål; Jonsdottir, Olga Hrønn; Reseland, Janne Elin & Bjørnland, Tore (2020). Incidence of alveolar osteitis after mandibular third molar surgery. Can inflammatory cytokines be identified locally? Acta Odontologica Scandinavica. ISSN 0001-6357. 79(3), s. 205–211. doi: 10.1080/00016357.2020.1817546. Fulltekst i vitenarkiv
• Hesse, Juliane; Schmalfuss, Andreas Jörn & Kvaal, Sigrid Ingeborg (2020). Photodynamic therapy of oral lichen planus. Photochemical and Photobiological Sciences. ISSN 1474-905X. 19, s. 1271–1279. doi: 10.1039/d0pp00249f.
• Aqrawi, Lara A.; Chen, Xiangjun; Hynne, Håvard; Amdal, Cecilie Delphin; Reppe, Sjur & Aass, Hans Christian Dalsbotten [Vis alle 14 forfattere av denne artikkelen] (2020). Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways. Cells. ISSN 2073-4409. 9(9). doi: 10.3390/cells9092050. Fulltekst i vitenarkiv
• Aqrawi, Lara Adnan; Jensen, Janicke Cecilie Liaaen; Fromreide, Siren; Galtung, Hilde Kanli & Skarstein, Kathrine (2020). Expression of NGAL-specific cells and mRNA levels correlate with inflammation in the salivary gland, and its overexpression in the saliva, of patients with primary Sjögren’s syndrome. Autoimmunity. ISSN 0891-6934. s. 1–11. doi: 10.1080/08916934.2020.1795140. Fulltekst i vitenarkiv
• Skaare, Anne B; Szyszko, Ewa Alicja; Herlofson, Bente Brokstad & Søland, Tine Merete (2020). Orofacial granulomatosis: a questionnaire study among Norwegian dental clinicians. European Archives of Paediatric Dentistry. ISSN 1818-6300. 21(5), s. 557–564. doi: 10.1007/s40368-020-00511-3.
• Khalafalla, Mahmoud G.; Woods, Lucas T.; Jasmer, Kimberly J.; Forti, Kevin Munoz; Camden, Jean M. & Jensen, Janicke Liaaen [Vis alle 9 forfattere av denne artikkelen] (2020). P2 receptors as therapeutic targets in the salivary gland: From physiology to dysfunction. Frontiers in Pharmacology. ISSN 1663-9812. 11:222, s. 1–223. doi: 10.3389/fphar.2020.00222. Fulltekst i vitenarkiv
• Giltvedt, KM; Bjørnland, Tore & Olsen-Bergem, Heming (2020). Hvordan håndtere pasienter med økt blødningsrisiko. Den norske tannlegeforenings tidende. ISSN 0029-2303. 130, s. 318–324.
• Tashbayev, Behzod; Garen, Torhild Oddveig; Palm, Øyvind; Chen, Xiangjun; Herlofson, Bente Brokstad & Young Vik, Alix Rosslyn [Vis alle 13 forfattere av denne artikkelen] (2020). Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study. Scientific Reports. ISSN 2045-2322. doi: 10.1038/s41598-020-59078-0. Fulltekst i vitenarkiv
• Loro, Lado Lako & Bjørnland, Tore (2020). Calcium pyrophosphate deposition disease: a case report with bilateral involvement of the temporomandibular joints and concurrence of psoriatic arthritis. Clinical Case Reports. ISSN 2050-0904. 8(4), s. 640–643. doi: 10.1002/ccr3.2715. Fulltekst i vitenarkiv
• Lund, Bodil Kristina; Ulmner, Mattias; Bjørnland, Tore; Berge, Trond Inge; Olsen-Bergem, Heming & Rosén, Annika (2020). A disease-focused view on the temporomandibular joint using a Delphi-guided process. Journal of Oral Science. ISSN 1343-4934. 62(1), s. 1–8. doi: 10.2334/josnusd.19-0128.
• Xiao, Jiaxin; Adil, Muhammed Yasin; Chen, Xiangjun; Utheim, Øygunn A.; Ræder, Sten & Tønseth, Kim Alexander [Vis alle 9 forfattere av denne artikkelen] (2019). Functional and Morphological Evaluation of Meibomian Glands in the Assessment of Meibomian Gland Dysfunction Subtype and Severity. American Journal of Ophthalmology. ISSN 0002-9394. 209, s. 160–167. doi: 10.1016/j.ajo.2019.09.005. Fulltekst i vitenarkiv
• Skarstein, Kathrine; Jensen, Janicke Liaaen; Galtung, Hilde; Jonsson, Roland; Brokstad, Karl Albert & Aqrawi, Lara A. (2019). Autoantigen-specific B cells and plasma cells are prominent in areas of fatty infiltration in salivary glands of patients with primary Sjogren?s syndrome. Autoimmunity. ISSN 0891-6934. 52, s. 242–250. doi: 10.1080/08916934.2019.1684475.
• Xiao, Jiaxin; Adil, Muhammed Yasin; Olafsson, Jonatan; Chen, Xiangjun; Utheim, Øygunn Aass & Ræder, Sten [Vis alle 9 forfattere av denne artikkelen] (2019). Diagnostic Test Efficacy of Meibomian Gland Morphology and Function. Scientific Reports. ISSN 2045-2322. 9(1). doi: 10.1038/s41598-019-54013-4. Fulltekst i vitenarkiv
• Jackson, Catherine; Ernø, Inger Thea Myklebust; Ringstad, Håkon; Tønseth, Kim Alexander; Dartt, Darlene Ann & Utheim, Tor Paaske (2019). Simple limbal epithelial transplantation: Current status and future perspectives: Concise review. Stem Cells Translational Medicine. ISSN 2157-6564. s. 1–13. doi: 10.1002/sctm.19-0203. Fulltekst i vitenarkiv

Se alle arbeider i Cristin

• Bjørnland, Tore (2021). Nordic Textbook of Oral and Maxillofacial Surgery. Munksgaard Forlag. ISBN 978-87-628-2012-8. 567 s.

Se alle arbeider i Cristin

• Khatri, Bhuwan; Tessneer, Kandice L.; Rasmussen, Astrid; Aghakhanian, Farhang; Reksten, Tove Ragna & Adler, Adam [Vis alle 66 forfattere av denne artikkelen] (2022). Erratum: Author Correction: Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells (Nature communications (2022) 13 1 (4287)). Nature Communications. ISSN 2041-1723. 13(1). doi: 10.1038/s41467-022-34311-8.
• Frigaard, Julie Mari; Hynne, Håvard; Randsborg, Karoline; Mellin-Olsen, Tonje; Young, Alix & Rykke, Morten [Vis alle 10 forfattere av denne artikkelen] (2022). Oral health indicators, oral health-related quality of life and nutritional aspects in medicated patients suffering from anxiety, psychosis, and/or depression. Frontiers in Public Health. ISSN 2296-2565.
• Frigaard, Julie Mari; Hynne, Håvard; Young, Alix; Hove, Lene Hystad; Rykke, Morten & Singh, Preet Bano [Vis alle 7 forfattere av denne artikkelen] (2022). Do medicated psychiatric patients differ from other dry mouth patients? .
• Jensen, Janicke Liaaen (2022). Tann- og munnhelsens betydning for eldres ernæring.
• Jensen, Janicke Liaaen (2022). Dry mouth and oral health-related quality of life in various conditions including EDs.
• Jensen, Janicke Liaaen (2022). Interprofessional collaboration on integrating oral and general health for the elderly in various care settings.
• Monsen, Ragnhild Elisabeth; Nordgarden, Hilde; Gay, Caryl; Lerdal, Anners & Herlofson, Bente Brokstad (2022). Munntørrhet - et manglende symptom i Edmonton Symptom Assessment System?
• Monsen, Ragnhild Elisabeth; Kristoffersen, Anne Karin; Gay, Caryl; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Vis alle 10 forfattere av denne artikkelen] (2022). Orale soppinfeksjoner - mer enn Candida albicans: mikrobiologiske analyser av prøver fra alvorlig syke pasienter med kreft . Vis sammendrag

  Bakgrunn Pasienter med alvorlig kreftsykdom er utsatte for orale soppinfeksjoner, grunnet sykdommen, kreftbehandling og/eller svekket immunforsvar. Orale soppinfeksjon påvirker pasienters matlyst, ernæringstilstand og livskvalitet. Candida albicans er en vanlig soppart i munnhulen, men forekomst av non-albicans Candida-arter, og i kombinasjon med C. albicans, er økende. Artene har varierende toleranse for antimykotiske midler, det kan gi behandlingsutfordringer. Hensikten med studien var å identifisere og resistensteste Candida sopparter i munnhulen til alvorlig syke pasienter med kreft. Metode Sopprøver tatt under studien Oral Health in Advanced Cancer i perioden 2014 – 2016, ble analysert høsten 2020. Pasientprøvene ble re-dyrket ved Institutt for oral biologi, Universitetet i Oslo. Soppartene ble identifisert biokjemisk og ved DNA sekvensering, og resistenstestet for antimykotiske legemidler: fluconazole, amphotericin B, anidulafungin og nystatin. Resultat Vi analyserte totalt 56 isolater fra 45 pasienter og identifiserte syv Candida arter og en Saccharomyces. Til sammen hadde 36 pasienter oppvekst av én soppart, og 9 pasienter hadde 2 til 3 ulike sopparter i munnhulen. Av C. albicans artene var 39 av 40 følsomme for fluconazole. To Candida parapsilosis og en Candida tropicalis var resistent mot anidulafungin. En C. tropicalis var resistent mot anidulafungin. En Candida glabrata var resistent mot fluconazole. Konklusjon Studien viste at forskjellige Candida arter forekommer både i monoinfeksjoner og blandingsinfeksjoner. C. albicans var dominerende med høy følsomhet for antimykotiske midler. Blandingsinfeksjoner kan komplisere behandlingen og forårsake gjentagende infeksjoner. Mikrobiologiske prøver og analyser med identifisering og resistenstesting, bør være en del av utredningen hos pasienter med alvorlig og tilbakevendende orale soppinfeksjoner.

• Monsen, Ragnhild Elisabeth; Kristoffersen, Anne Karin; Gay, Caryl; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Vis alle 10 forfattere av denne artikkelen] (2022). Oral candidiasis in advanced cancer – identification and susceptibility testing of detected Candida species. Vis sammendrag

  Introduction: Candida albicans is the most common fungal species in the oral cavity. Increased prevalence of non-C. albicans are detected, and co-infection with C. albicans may have implications for treatment, due to antifungal resistance. The aim of the study was to assess the diversity and susceptibility of oral yeasts in patients with advanced cancer. Methods: Clinical fungal isolates were sampled in 2014-2016 from 45 patients in a hospice unit. Totally 56 isolates were grown on chromID Candida plates, prepared for biochemical identification, and controlled with DNA sequencing. E-test was performed with the antifungal agents fluconazole, amphotericin B, anidulafungin and nystatin were tested. Results: A total of 56 isolates were identified. Candida species was dominated by C. albicans at 71%, followed by C. glabrata 9%, C. parapsilosis 5%, C. tropicalis 4%, C. krusei 2%, C. guilliermondii 2% and C. dubliniesis 2%. Nine patients had 2-3 different species. C. albicans strains were susceptible to fluconazole in 97.5%. One C. parapsilosis and one C. tropicalis strain were resistant to anidulafungin. One C. glabrata was resistant to fluconazole and another was just below the threshold for resistance. The sequencing confirmed the biochemical identification. Conclusion: C. albicans was the most prevalent species. Variation in susceptibility was observed in patients with mixed colonies. Combinations of Candida species and the lack of identification and susceptibility testing may lead to inadequate treatment.

• Monsen, Ragnhild Elisabeth; Kristoffersen, Anne Karin; Gay, Caryl; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Vis alle 10 forfattere av denne artikkelen] (2022). Identification and susceptibility testing of oral candidiasis in advanced cancer patients – an important diagnostic tool. Vis sammendrag

  Background: Candida albicans is the most common fungal species detected in the oral cavity. Studies of oral fungal samples have shown an increased prevalence of non-C. albicans species in mixed infection with C. albicans. Non-C. albicans and C. albicans are associated with varying degrees of resistance to azole. This may have implications for treatment, due to acquired antifungal resistance. Aims: To assess the diversity and susceptibility of detected Candida species in the oral cavity in patients with advanced cancer. Methods: Clinical fungal isolates sampled in 2014-2016 from 45 patients in a hospice unit were analyzed. A total of 56 isolates were grown on chromID Candida plates. After phenotypic identification by colour of the colonies, one single colony of each species was re-cultivated and prepared for identification on a VITEK2® system. Susceptibility testing with E-test was performed on RPMI agar, and the antifungal agents fluconazole, amphotericin B, anidulafungin and nystatin were tested. Results: A total of 56 Candida isolates were identified. The diversity of Candida species was dominated by C. albicans at 89%, followed by C. glabrata 11%, C. parapsilosis 7%, C. tropicalis 4%, C. krusei 2%, C. guilliermondii 2% and C. dubliniesis 2%. Thirty-six patients had monoculture, and nine patients had 2-3 different species detected. Almost all C. albicans strains (97.5%) were susceptible to fluconazole. One C. parapsilosis and one C. tropicalis strain were resistant to anidulafungin. One C. glabrata was resistant to fluconazole and another was just below the threshold for resistance. Conclusion: C. albicans was the most prevalent Candida species in our sample. Variation in susceptibility was observed in patients with both C. albicans and C. glabrata. Combinations of Candida species and the lack of identification and susceptibility testing may lead to inadequate treatment and accelerate the development of resistance.

• Bjørk, Mai Britt; Kvaal, Sigrid Ingeborg; Bleka, Øyvind; Sakinis, Tomas; Tuvnes, Frode A. & Lauritzen, Peter Mæhre [Vis alle 8 forfattere av denne artikkelen] (2022). MRI segmentation of 3rd molar tooth tissue volumes to predict age older than 18 years in sub-adults.
• Hol, Caroline; Arvidsson, Linda Zamoline; Larheim, Tore Arne; Bjørnland, Tore & Mork-Knutsen, Peer Olaf (2022). Radiologically diagnosed temporomandibular joint osteoarthritis 10 and 30 years after diskectomy.
• Jensen, Janicke Liaaen; Barkvoll, Pål & Cetrelli, Patrik (2021). Én innbygger – to journaler. Dagens medisin. ISSN 1501-4290.
• Hynne, Håvard; Sandås, Elise Mørk; Elgstøen, Katja B. Prestø; Rootwelt, Helge; Galtung, Hilde Kanli & Utheim, Tor Paaske [Vis alle 7 forfattere av denne artikkelen] (2021). Metabolomics Identify Patterns Indicating Potential Biomarkers in Primary Sjögren’s Syndrome .
• Hynne, Håvard; Aqrawi, Lara A.; Chen, Xiangjun; Amdal, Cecilie Delphin; Reppe, Sjur & Aass, Hans Christian Dalsbotten [Vis alle 14 forfattere av denne artikkelen] (2021). Cytokine profiling, clinical oral and ocular manifestations post radiotherapy .
• Frigaard, Julie Mari (2021). Home PCR.
• Frigaard, Julie Mari (2021). Development of a new liposomal product for dry mouth relief.
• Herlofson, Bente Brokstad (2021). Munnhulekreft - Orale potensielt maligne tilstander, orale alarmsymptomer Pasienter på benmodulerende behandling.
• Herlofson, Bente Brokstad (2021). Pasienter på antiresorptiv behandling og kjeveosteonekrose.
• Bjørkeng, Astrid Skiftesvik; Herlofson, Bente Brokstad & Myhre, Sigrun (2021). Podkast: Hvordan virker kreftbehandling på kroppen? [Internett]. Universitetet i Oslo, Universitetsplassen podkast.
• Herlofson, Bente Brokstad (2021). Hvordan forholde seg til pasienter på benmodulerende behandling - Når kan tenner ekstraheres?
• Herlofson, Bente Brokstad (2021). Munnhelse ved kreft og kreftbehandling.
• Herlofson, Bente Brokstad; Lund, Bodil Kristina; Pinholt, Else Marie & Seppänen-Kaijansinkko, Riitta (2021). The Nordic Success Story - Four women in Oral and maxillofacial Surgery from four Nordic countries. Face to Face, Magazine, IAOMS.
• Frigaard, Julie Mari; Jensen, Janicke Liaaen; Galtung, Hilde & Hiorth, Marianne (2021). Development of a Liposomal Dry Mouth Product for Long-term Relief.
• Jensen, Janicke Liaaen (2021). The Dry Mouth Clinic – what is it all about?
• Jensen, Janicke Liaaen (2021). Har pasienten Sjögrens syndrom?
• Jensen, Janicke Liaaen (2021). Min Forskning: Fra lab til pasient til samfunnet.
• Young, Alix; Jensen, Janicke Liaaen; Hove, Lene Hystad; Fjeld, Katrine Gahre & Blich, Carl Christian (2021). Et smil uten smerter? Dagens medisin. ISSN 1501-4290.
• Jensen, Janicke Liaaen (2021). Ut med tannhelse – inn med munnhelse som begrep! Dagens medisin. ISSN 1501-4290.
• Herlofson, Bente Brokstad; Schiødt, Morten & Wexell, Cecilia Larsson (2021). Acute and chronic inflammation, osteomyelitis, medication-related ostoenecrosis of the jaw and osteoradionecrosis. I Bjørnland, Tore (Red.), Nordic Textbook of Oral and Maxillofacial Surgery. Munksgaard Forlag. ISSN 978-87-628-2012-8. s. 151–182.
• Bjørnland, Tore & Møystad, Anne (2021). Temporomandibular joint disorders. I Bjørnland, Tore (Red.), Nordic Textbook of Oral and Maxillofacial Surgery. Munksgaard Forlag. ISSN 978-87-628-2012-8. s. 471–492.
• Olsen-Bergem, Heming & Bjørnland, Tore (2021). Hematological considerations. I Bjørnland, Tore (Red.), Nordic Textbook of Oral and Maxillofacial Surgery. Munksgaard Forlag. ISSN 978-87-628-2012-8. s. 61–75.
• Jensen, Janicke Liaaen; Barkvoll, Pål & Bjørnland, Tore (2021). Extra- and intraoral examination. I Bjørnland, Tore (Red.), Nordic Textbook of Oral and Maxillofacial Surgery. Munksgaard Forlag. ISSN 978-87-628-2012-8. s. 19–30.
• Jensen, Janicke Liaaen (2021). Mye kunnskap om sjeldenhet. [Fagblad]. Nor Tannlegeforen Tid.
• Jensen, Janicke Liaaen (2021). God tannhelse = god helse i fremtiden. [Tidsskrift]. Tara.
• Jensen, Janicke Liaaen (2021). Sammenhengen mellom oral og generell helse.
• Diep, My Tien; Jensen, Janicke Liaaen; Sødal, Anne Thea Tveit; Young, Alix; Skudutyte-Rysstad, Rasa & Hove, Lene Hystad (2020). Are Xerostomia and Hyposalivation Common Problems Among 65-Year-Olds? Caries Research. ISSN 0008-6568. 54(4), s. 449–450. doi: 10.1159/000511860.
• Skaare, Anne B; Herlofson, Bente Brokstad & Søland, Tine Merete (2020). Orofacial granulomatose og Crohns sykdom – et klinisk kasus og en litteraturgjennomgang. Den norske tannlegeforenings tidende. ISSN 0029-2303. 130(11), s. 914–920.
• Sødal, Anne Thea Tveit; Singh, Preet Bano; Diep, My Tien & Hove, Lene Hystad (2020). Prevalence of Smell, Taste, Trigeminal Disorders and Quality of Life Among 65-Year-Olds in Oslo. Caries Research. ISSN 0008-6568. 54(4), s. 449–449. doi: 10.1159/000511860.
• Herlofson, Bente Brokstad (2020). Pasienter på benmodulerende behandling og osteonekrose - med fokus på myelomatose.
• Herlofson, Bente Brokstad (2020). Jaw osteomyelitis/osteonecrosis - clinical presentation, diagnosis, therapy.
• Steffensen, Inger-Lise; Alexander, Jan; Binderud, Mona-Lise; Bruzell, Ellen Merete; Dahl, Knut Helkås & Granum, Berit [Vis alle 13 forfattere av denne artikkelen] (2020). Risk assessments of aspartame, acesulfame K, sucralose and benzoic acid from soft drinks, "saft", nectar and flavoured water. European Journal of Nutrition and Food Safety. ISSN 2347-5641. 12(8), s. 66–68. doi: 10.9734/EJNFS72020/v12i830265.
• Herlofson, Bente Brokstad (2020). Kreftpasienter på antiresorptiv behandling med risiko for utvikling av osteonekrose i kjevene.
• Herlofson, Bente Brokstad (2020). Pasienter på benmodulerende behandling og osteonekrose.
• Jensen, Janicke Liaaen (2020). Integrated oral and general health.
• Jensen, Janicke Liaaen (2020). Eldres munnehelse går under radaren. Forskning.no. ISSN 1891-635X.
• Jensen, Janicke Liaaen (2020). Hvordan påvirker revmatiske sykdommer generelt, og Sjögrens syndrom spesielt, oral helse?
• Sapkota, Dipak; Thapa, Suraj Bahadur; Hasseus, Bengt & Jensen, Janicke Liaaen (2020). Saliva testing for COVID-19? British Dental Journal. ISSN 0007-0610. doi: 10.1038/s41415-020-1594-7.
• Jensen, Janicke Liaaen (2020). Bærekraftig alderdom - en sunn sjel med en sunn munnhule i et sunt lege.
• Jensen, Janicke Liaaen (2020). Innledningsforedrag: Økt fokus på eldres munnhelse .
• Herlofson, Bente Brokstad (2019). Pasienter som skal ha eller som står på på benmodulerende behandling - samarbeid mellom lege og tannlege.

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